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61.
62.
Nanoengineering Hybrid Supramolecular Multilayered Biomaterials Using Polysaccharides and Self‐Assembling Peptide Amphiphiles 下载免费PDF全文
Developing complex supramolecular biomaterials through highly dynamic and reversible noncovalent interactions has attracted great attention from the scientific community aiming key biomedical and biotechnological applications, including tissue engineering, regenerative medicine, or drug delivery. In this study, the authors report the fabrication of hybrid supramolecular multilayered biomaterials, comprising high‐molecular‐weight biopolymers and oppositely charged low‐molecular‐weight peptide amphiphiles (PAs), through combination of self‐assembly and electrostatically driven layer‐by‐layer (LbL) assembly approach. Alginate, an anionic polysaccharide, is used to trigger the self‐assembling capability of positively charged PA and formation of 1D nanofiber networks. The LbL technology is further used to fabricate supramolecular multilayered biomaterials by repeating the alternate deposition of both molecules. The fabrication process is monitored by quartz crystal microbalance, revealing that both materials can be successfully combined to conceive stable supramolecular systems. The morphological properties of the systems are studied by advanced microscopy techniques, revealing the nanostructured dimensions and 1D nanofibrous network of the assembly formed by the two molecules. Enhanced C2C12 cell adhesion, proliferation, and differentiation are observed on nanostructures having PA as outermost layer. Such supramolecular biomaterials demonstrate to be innovative matrices for cell culture and hold great potential to be used in the near future as promising biomimetic supramolecular nanoplatforms for practical applications. 相似文献
63.
Assembly and Characterizations of Bifunctional Fluorescent and Magnetic Microneedles With One Decade Length Tunability 下载免费PDF全文
Jean‐Baptiste Lugagne Gwennhaël Brackx Emek Seyrek Sophie Nowak Yann Sivry Leticia Vitorazi Jean‐François Berret Pascal Hersen Gaëlle Charron 《Advanced functional materials》2017,27(31)
This report presents the fabrication of bifunctional magnetic and fluorescent microneedles (µNDs) made of a ternary mixture of magnetic nanoparticles (NPs), quantum dots (QDs), and polyelectrolyte. The assembly relies on the electrostatic complexation of negatively charged NPs with positively charged polymer strands and is controlled by the charge ratio between the nanoparticle building blocks and the polymer mortar. The resulting 1D objects can be actuated using an external magnetic field and can be imaged using fluorescence microscopy, thanks to the fluorescent and superparamagnetic properties inherited from their NP constituents. Using a combination of core and surface characterizations and a state‐of‐the‐art image analysis algorithm, the dependence of the brightness and length on the ternary composition is thoroughly investigated. In particular, statistics on hundreds of µNDs with a range of compositions show that the µNDs have a log‐lormal length distribution and that their mean length can be robustly tuned in the 5–50 µm range to match the relevant length scales of various applications in micromixing, bioassays or biomechanics. 相似文献
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基于超晶格量子阱的双稳态效应,在经典力学框架内,把粒子的运动方程化为了具有阻尼项和受迫项的摆方程.利用Melnikov方法分析了系统的全局分叉与Smale马蹄变换意义上的混沌行为,给出了系统通过级联分叉进入混沌的临界值.结果表明,系统进入混沌的临界条件与它的参数有关,只需适当调节这些参数就可以避免或控制混沌,为光学双稳态器件的设计提供了理论分析. 相似文献
66.
为满足低等级红外探测器组件在高可靠性领域的空间应用需求,对星载红外探测器组件进行温度循环试验、力学试验以及高温老炼试验等环境试验考核,并基于双积分球式均匀照明系统对环境试验前后红外探测器组件相对光谱响应率进行测试。通过对比环境试验前后红外探测器组件相对光谱响应率变化,分析红外探测器组件的环境适应性,揭示红外探测器组件的质量缺陷及其他潜在缺陷,剔除早期失效,并从参试红外探测器组件中筛选出性能优良的探测器应用在星载偏振扫面仪进行大气偏振探测。试验结果表明:参试的红外探测器组件在环境试验前后具有良好的稳定性和可靠性,可以满足航天载荷应用需求。 相似文献
67.
Yuki Hirai Hirosato Monobe Norihiro Mizoshita Masaya Moriyama Kenji Hanabusa Yo Shimizu Takashi Kato 《Advanced functional materials》2008,18(11):1668-1675
Discotic liquid‐crystalline (LC) physical gels have been prepared by combining the self‐assembled fibers of a low‐molecular‐weight gelator and semiconducting LC triphenylene derivatives. The hole mobilities of the discotic LC physical gels measured by a time‐of‐flight method become higher than those of LC triphenylenes alone. The introduction of the finely dispersed networks of the gelator in the hexagonal columnar phases may affect the molecular dynamics of the liquid crystals, resulting in the enhancement of hole transporting behavior in the LC gel state. 相似文献
68.
综述了环氧树脂基的PCB与无铅化组装的兼容性问题。经过大量试验表明,常规的FR-4基材和双氰胺固化的高Tg基材是不能满足无铅化组装要求的,而采用酚醛固化的中等-Tg的环氧树脂基材是可能成为无铅化组装用基材的。同时,PCB制造过程也起着重要的作用。PCB设计和再(回)流焊的加热梯度也影响着无铅化的性能。 相似文献
69.
Efficient use of (nano)particle self‐assembly for creating nanostructured materials requires sensitive control over the interactions between building blocks. Here, a very simple method for rendering the interactions between almost any hydrophobic nano‐ and microparticles thermoswitchable is described and this attraction is characterized using colloid probe atomic force microscopy (CP‐AFM). In a single‐step synthesis, a thermoresponsive surfactant is prepared that through physical adsorption generates a thermosensitive brush on hydrophobic surfaces. These surface layers can reversibly trigger gelation and crystallization of nano‐ and microparticles, and at the same time can be used to destabilize emulsions on demand. The method requires no chemical surface modification yet is universal, reproducible, and fully reversible. 相似文献
70.
为了研究Furuta摆在倒立点附近的稳定控制问题,采用基于T-S模糊模型的一类连续模糊动态系统控制方法,首次进行Furuta摆的模糊状态空间建模,并采用模糊切换的思想,设计了Furuta摆在倒立点附近的稳定控制器,进而分析了系统稳定性。与已有的方法相比,该方法的优点是稳定区域大、调节时间短。数字仿真结果验证了方法的有效性。 相似文献