基于属性变化的增量关联规则挖掘

关联规则的挖掘是数据挖掘研究中的一个重要课题,目前已经提出了许多用于发现海量事务库中关联规则的算法以及更新已经发现的关联规则的算法。但是在关联规则的更新算法中,都是基于支持度变化和事务库变化的研究,目前没有人研究当事务库中的属性发生变化时,如何高效地更新关联规则的问题。针对这种情况,提出了三种基于属性变化的增量关联规则挖掘算法ACA+（Attribute Change Algorithm）和ACA-（ACA1-）,从而解决了该问题。     

基于“双芯”51内核的学习机设计

嵌入式系统在教育领域的应用产生了各种类型的学习机,重点论述了一种基于M CS-51内核的“双芯”的嵌入式学习机系统,满足了职业学校学生录入练习的需求。通过对这个系统的分析和论述提出一种在51内核上运行复杂系统的方法。     

施威德勒型单层球面网壳结构抗火的非线性有限元分析

根据ISO-834标准升温曲线与结构钢强度和刚度随温度的变化曲线,采用非线性有限元法对不同的矢跨比的施威德勒型单层球面网壳结构进行了抗火分析,得到了一些结果,可为经济、科学的结构综合防火设计提供理论依据.     

预应力混凝土柱的施工技术

偏心受压钢筋混凝土柱,采用预应力技术减小或避免钢筋混凝土柱根部裂缝,通过在钢筋混凝土柱受拉区一侧预先施加一定的力,使钢筋混凝土柱内部受力在新的条件下建立平衡.实践证明:该方法能有效地控制柱截面,解决钢筋混凝土柱偏心受压的根部裂缝问题.     

Genetic LGALS1 Variants Are Associated with Heterogeneity in Galectin-1 Serum Levels in Patients with Early Arthritis

Galectin 1 (Gal1) exerts immunomodulatory effects leading to therapeutic effects in autoimmune animal models. Patients with rheumatoid arthritis have been reported to show higher Gal1 serum levels than the healthy population. Our study aimed to find genetic variants on the Gal1 gene (LGALS1) modulating its expression and/or clinical features in patients with early arthritis (EA). LGALS1 was sequenced in 53 EA patients to characterize all genetic variants. Then, we genotyped rs9622682, rs929039, and rs4820293, which covered the main genetic variation in LGALS1, in 532 EA patients. Gal1 and IL-6 serum levels were measured by ELISA and Gal1 also by western blot (WB) in lymphocytes from patients with specific genotypes. Once disease activity improved with treatment, patients with at least one copy of the minor allele in rs9622682 and rs929039 or those with GG genotype in rs4820293 showed significantly higher Gal1 serum levels (p < 0.05). These genotypic combinations were also associated with higher Gal1 expression in lymphocytes by WB and lower IL-6 serum levels in EA patients. In summary, our study suggests that genetic variants studied in LGALS1 can explain heterogeneity in Gal1 serum levels showing that patients with higher Gal1 levels have lower serum IL-6 levels.     

基于改进VGG网络的单体热电池X光图像无损检测方法研究

为解决单体热电池生产中出现的安装错误、人工检测耗时耗力的问题,提出一个结合迁移学习和卷积 神 经网络(convolutional neural network,CNN) 的单体热电池缺陷检测模型。首先,对数据集图像进行裁剪、加噪等预处理,以VGG16(visual geometry group 16) 网络作为 模型的骨干架构,在瓶颈层后增添选择性核(selective kernel,SK) 卷积;然后,增添全局平均池化(global average pooling,GAP) 层, 增加Dropout层及添加 L2 正则化等微调操作,得到单体热电池缺陷检测模型Q-VGGNet;最后,在大型公开数据集ImageNet上进 行预训练学习,将获得的权重参数迁移到单体热电池图像识别模型Q-VGGNet上。测试实验表明:6种 网络模型对数据集缺陷图像的总体识别准确率分别达到了98.39%、94.44%、97.27%、96.34%、93.71%、 95.61%,Q-VGGNet网 络模型 对合格图像和 漏装负极、极耳断裂、漏装集流片3种缺陷图像 识别准确率 分别达到了99.6%,95.9%,99.6%和98.4%。检测结果表明:该方法能够更准确、快速地检测热电池缺陷, 拥有良好的缺陷诊断能力,较传统方法提高近3%,为人工检测单体热电池缺陷提供了良好的解决途径。     

Gene Variants Related to Cardiovascular and Pulmonary Diseases May Correlate with Severe Outcome of COVID-19

Background: Severe outcomes of COVID-19 account for up to 15% of all cases. The study aims to check if any gene variants related to cardiovascular (CVD) and pulmonary diseases (PD) are correlated with a severe outcome of COVID-19 in a Polish cohort of COVID-19 patients. Methods: In this study, a subset of 747 samples from unrelated individuals collected across Poland in 2020 and 2021 was used and whole-genome sequencing was performed. Results: The GWAS analysis of SNPs and short indels located in genes related to CVD identified one variant significant in COVID-19 severe outcome in the HADHA gene, while for the PD gene panel, we found two significant variants in the DRC1 gene. In this study, both potentially protective and risk variants were identified, of which variants in the HADHA gene deserve the most attention. Conclusions: This is the first study reporting the association between the HADHA and DRC1 genetic variants and COVID-19 severe outcome based on the cohort WGS analysis. Although all the identified variants are localised in introns, they may be correlated and therefore inherited along with other risk variants, potentially causative to severe outcome of COVID-19 but not discovered yet.     

基于边缘特征的单帧图像清晰度判定

自动调焦是保证目标跟踪系统实时获得清晰图像的重要技术,而何时触发调焦又成为了其中的关键问题。在图像清晰时如果触发调焦,初始的电机盲动会导致图像可能变得更模糊。提出了一种可单帧判断图像是否清晰的方法,消除了图像在清晰情况下却触发调焦的误操作,从而提高了跟踪的可靠性和精度。通过对多组实际图像序列的测试,证明该方法合理可靠。     

交换机系统割接方案

在全国电力系统的语音调度专网通信系统中,由于系统发展的需要,经常涉及到电话交换机的移机及割接。由于调度通信系统的重要性及特殊性,在交换机移机及割接过程中要保持通信的畅通,不能中断。在一些核心的大局的割接过程中,在业务复杂繁多的情况下,如何保证通信不中断,做到平滑、无缝的割接,是许多大局都面临的问题。详细介绍一种调度交换机割接并移机的方案,可以提供一些这方面的参考。     

十二脉动高压直流输电系统交流滤波器设计

在单极十二脉动高压直流输电系统PSCAD/EMTDC模型的基础上,仿真分析该系统未采取任何滤波装置时交流侧电流的谐波特点,依据谐波分析结果确定滤波方案,设计滤波器相关参数,并且运用MATLAB软件绘制滤波器的阻抗特性曲线,最后通过对比加装滤波器前后交流侧电流快速傅里叶变换分析结果,验证该滤波器设计方案的合理性.