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181.
This paper investigates a novel compound control scheme combined with the advantages of trajectory linearization control (TLC) and alternative active disturbance rejection control (ADRC) for hypersonic reentry vehicle (HRV) attitude tracking system with bounded uncertainties. Firstly, in order to overcome actuator saturation problem, nonlinear tracking differentiator (TD) is applied in the attitude loop to achieve fewer control consumption. Then, linear extended state observers (LESO) are constructed to estimate the uncertainties acting on the LTV system in the attitude and angular rate loop. In addition, feedback linearization (FL) based controllers are designed using estimates of uncertainties generated by LESO in each loop, which enable the tracking error for closed-loop system in the presence of large uncertainties to converge to the residual set of the origin asymptotically. Finally, the compound controllers are derived by integrating with the nominal controller for open-loop nonlinear system and FL based controller. Also, comparisons and simulation results are presented to illustrate the effectiveness of the control strategy.  相似文献   
182.
Temperature history can have a significant effect on the strength of water-saturated chalk.In this study,hydrostatic stress cycles are applied to understand the mechanical response of chalk samples exposed to temperature cycling between each stress cycle,compared to the samples tested at a constant temperature.The total accumulated strain during a stress cycle and the irreversible strain are reported.Chalk samples from Kansas(USA)and Mons(Belgium),with different degrees of induration(i.e.amount of contact cementation),were used.The samples were saturated with equilibrated water(polar)and nonpolar Isopar H oil to quantify water weakening.All samples tested during 10 stress cycles with varying temperature(i.e.temperature cycled in between each stress cycle)accumulated more strain than those tested at constant temperatures.All the stress cycles were performed at 30℃.The two chalk types behaved similarly when saturated with Isopar H oil,but differently when saturated with water.When saturated with water,the stronger Kansas chalk accumulated more total strain and more irreversible strain within each stress cycle than the weaker Mons chalk.  相似文献   
183.
The correct separation of chromosomes during mitosis is necessary to prevent genetic instability and aneuploidy, which are responsible for cancer and other diseases, and it depends on proper centrosome duplication. In a recent study, we found that Smy2 can suppress the essential role of Mps2 in the insertion of yeast centrosome into the nuclear membrane by interacting with Eap1, Scp160, and Asc1 and designated this network as SESA (S my2, E ap1, S cp160, A sc1). Detailed analysis showed that the SESA network is part of a mechanism which regulates translation of POM34 mRNA. Thus, SESA is a system that suppresses spindle pole body duplication defects by repressing the translation of POM34 mRNA. In this study, we performed a genome-wide screening in order to identify new members of the SESA network and confirmed Dhh1 as a putative member. Dhh1 is a cytoplasmic DEAD-box helicase known to regulate translation. Therefore, we hypothesized that Dhh1 is responsible for the highly selective inhibition of POM34 mRNA by SESA.  相似文献   
184.
Few literature studies have investigated the relationships between different uses and gratifications (U&Gs) of mobile instant messaging (MIM) apps, continuation, and purchase intentions. To address this gap, the researchers aimed to examine the influence of the content, social, process, and technology U&Gs of MIM on continuation intentions toward MIMs, and purchase intentions toward virtual goods available on MIMs. A comprehensive research model was developed based on the U&G theory, which was tested using cross-sectional data from 309 Japanese MIM users. The study considered six different U&Gs of MIM as independent variables and purchase intentions towards stickers and continuation intentions towards MIM as dependent variables. The study results suggest that exposure U&G has a significant positive association with MIM sticker purchase intentions. The entertainment and affection U&G are positively associated with continuation intentions towards MIM use. The study contributes to the literature by investigating U&Gs that motivate MIM users to have both positive purchase intentions toward virtual goods, such as stickers, and continuation intentions toward MIMs. The study has significant theoretical and practical implications for both researchers and practitioners who are interested in virtual goods, the virtual economy, MIM apps, social media, new media, and the service economy.  相似文献   
185.
The cyclooxygenase-2 (COX-2) is a potent enzyme that converts arachidonic acid to prostaglandins (PG), including PGE2, a key mediator of inflammation and angiogenesis. Importantly, COX-2 is activated in response to inflammatory stimuli, where it is also believed to promote the development and progression of head and neck cancers (HNC). COX-2 can mediate its protumorigenic effect through various mechanisms, such as inducing cell proliferation, inhibition of apoptosis, and suppressing the host’s immune response. Furthermore, COX-2 can induce the production of vascular endothelial growth factors, hence, promoting angiogenesis. Indeed, the ability of COX-2 inhibitors to selectively restrict the proliferation of tumor cells and mediating apoptosis provides promising therapeutic targets for cancer patients. Thus, in this comprehensive review, we summarized the reported differential expression patterns of COX-2 in different stages of head and neck carcinogenesis—from potentially premalignant lesions to invasive carcinomas. Furthermore, we examined the available meta-analysis evidence for COX-2 role in the carcinogenesis of HNC. Finally, further understanding of the biological processes of COX-2 and its role in orchestrating cell proliferation, apoptosis, and angiogenesis may give therapeutically beneficial insight to develop the management plan of HNC patients and improve their clinical outcomes.  相似文献   
186.
Assembly line balancing is important for the efficiency of the assembly process, however, a wide range of disruptions can break the current workload balance. Some researchers explored the task assignment plan for the assembly line balancing problem with the assumption that the assembly process is smooth with no disruption. Other researchers considered the impacts of disruptions, but they only explored the task re-assignment solutions for the assembly line re-balancing problem with the assumption that the re-balancing decision has been made already. There is limited literature exploring on-line adjustment solutions (layout adjustment and production rate adjustment) for an assembly line in a dynamic environment. This is because real-time monitoring of an assembly process was impossible in the past, and it is difficult to incorporate uncertainty factors into the balancing process because of the randomness and non-linearity of these factors. However, Industry 4.0 breaks the information barriers between different parts of an assembly line, since smart, connected products, which are enabled by advanced information and communication technology, can intelligently interact and communicate with each other and collect, process and produce information. Smart control of an assembly line becomes possible with the large amounts of real-time production data in the era of Industry 4.0, but there is little literature considering this new context. In this study, a fuzzy control system is developed to analyze the real-time information of an assembly line, with two types of fuzzy controllers in the fuzzy system. Type 1 fuzzy controller is used to determine whether the assembly line should be re-balanced to satisfy the demand, and type 2 fuzzy controller is used to adjust the production rate of each workstation in time to eliminate blockage and starvation, and increase the utilization of machines. Compared with three assembly lines without the proposed fuzzy control system, the assembly line with the fuzzy control system performs better, in terms of blockage ratio, starvation ratio and buffer level. Additionally, with the improvement of information transparency, the performance of an assembly line will be better. The research findings shed light on the smart control of the assembly process, and provide insights into the impacts of Industry 4.0 on assembly line balancing.  相似文献   
187.
The size-controlled preparation of Mo powders is always a challenge and important task in the molybdenum metallurgy. In the current study, Mo powders with controllable sizes are synthesized by hydrogen reduction of MoO2 powders with the assistance of Mo nuclei in the range of 900–1100 °C. The influences of the particle sizes of Mo nuclei, the additive amount as well as reaction temperature on the morphology and particle sizes of the final products are studied. For the hydrogen reduction of MoO2 without any additive, the obtained Mo powders always have large particle sizes. However, the addition of small amounts of nuclei in MoO2 can help Mo nucleate dispersedly, and the growth of Mo could be also controlled by adjusting the sizes of added nuclei, amount of addition and the reaction temperature. With the addition of Mo nuclei, the different sizes of Mo powders with the good dispersity can be prepared. As adding commercial Mo powders with the particle size of about 2.03 μm, the micron-sized Mo powders ranged from 2.11 μm to 3.25 μm could be prepared. While for the case of adding ultrafine Mo nuclei of about 170 nm, Mo powders from 0.28 μm to 0.88 μm can be obtained. Moreover, the more the amounts of nuclei added and the lower the reaction temperature (in the range of 900–1100 °C) is, the smaller the particle size of the prepared Mo powder will be. The current method is a facile and feasible method, and is potential to be used for industrial production of Mo powder with controllable particle sizes.  相似文献   
188.
针对新桥煤矿2301综采工作面机载喷雾系统喷雾效果差、喷雾耗水量大造成煤质含水量超标、喷嘴雾化程度不高、喷嘴容易发生堵塞等问题,提出了高压喷雾系统设计方案,选择了1.2mm的锥形引射喷嘴和1.5mm的扇形引射喷嘴。采用固定水泵供水方式,结合工作面实际情况,计算出喷雾总用水量247.5L/min,提高了喷雾射程,提升了除尘效果。  相似文献   
189.
Here, we report a facile approach to electrostatically couple the surface charges of graphite nanoplate (GNP) fillers and poly(methyl methacrylate) (PMMA) polymer particles using ethylene maleic anhydride (EMA) copolymer as an electrostatic coupling agent. Our strategy involved switching the intrinsic repulsive electrostatic interactions between the directly exfoliated GNPs fillers and the PMMA particles to attractive electrostatic surface interactions for preparing core(PMMA)-shell (GNP) precursor in order to optimizing 3-dimensionally dispersed polymer nanocomposite. As a result, the electrical conductivity of the composites dramatically increased by a factor of 16.7 in the EMA-coupled GNP/PMMA composites compared with that of the EMA-free GNP/PMMA composites. In addition, the percolation threshold was also notably reduced from 0.32 to 0.159 vol% after electrostatic coupling of the GNPs fillers and PMMA particles. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020 , 137, 48390.  相似文献   
190.
Nano crystalline pure and Mg doped ceriaparticles were synthesized by simple chemical co-precipitation method using cerium nitrate hexahydrate as a source material and magnesium nitrate as doping precursor at room temperature. The effect of doping were investigated by X-ray diffraction pattern(XRD), FT-Raman,fourier transform infrared spectroscopy(FTIR), Ultraviolet spectroscopy(UV), photoluminescence spectroscopy(PL), field emission scanning electron microscope(FESEM) and high resolution transmission electron microscopy with energy dispersive spectroscopy (HRTEM &EDS). The X-ray diffraction pattern and FT-Raman studies showed that the prepared samples were nano particulates with cubic fluorite structure. The XRD pattern analysis showed that the size of the particles ranged from 13 to 20?nm, however 4?wt% Mg doping results in reduction of particle size compared with other doping concentrations. The effects of Mg concentration on various structural parameters of the prepared samples were also determined. The slight blue shift observed upon doping in UV–Vis absorption region around 330–360nmrecorded for reduction in particle size. The FTIR unveils the presence of Metal oxygen bonds below 700?cm?1in the prepared samples. All samples showed a broad emission band at 430?nm with linearly increasing intensity with respect to dopant concentrations. The Spherical morphology with weak agglomeration was identified through FESEM and HRTEM analysis. The elemental analysis of Ce, O and Mg were confirmed through EDS analysis.  相似文献   
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