RSA数字签名技术在信息化工程监理流程E化中的研究

提出的信息化工程监理流程的E化过程就是将监理流程通过现有的IT技术进行重新梳理、再造,达到电子化、网络化。将对在E化过程中数字签名的应用进行研究,以应对E化容易出现的伪造这一网络安全问题。主要讲述hash签名技术中单向散列函数对文件进行摘要处理,然后使用RSA公钥加密算法对摘要进行加密。也会对签名过程和验证过程给予解说。     

基于ARM的嵌入式语音存储系统设计

为了有效地节省语音数据的传输带宽和存储系统的磁盘空间,需要在保证语音质量的前提下尽可能降低其编码比特率。本设计采用经过优化的G．729语音压缩编译码算法,以ARM处理器为载体,开发的嵌入式语音存储系统可实现语音信号的海量存储,而且处理速度快、可靠性好、扩展方便。通过严格的测试和评估,该系统能够实现对大量语音数据的压缩和记录,各项指标基本达到了预期的水平。     

Infants' sensitivity to optical flow for controlling posture.

Infants' sensitivity to optical flow for controlling sitting and standing was tested using a "moving room" in which all of the walls moved together, or only the side walls or front wall moved. Two questions motivated this research. (a) is the optical flow necessary for inducing postural compensations spatially distributed in the optic array? (b) Do visually induced compensations follow a developmental progression, or alternatively, emerge all at once? Experiment 1 was designed to test postural compensations by 14-month-old infants capable of standing in the moving room. Experiment 2 was designed to test postural compensations by 5- to 9-month-old infants who were passively supported while sitting in the moving room. The results revealed that partial flow is generally sufficient for inducing postural compensations, but that the amplitude and consistency of the response depend on the location of the flow in the optic array. In addition, there was evidence suggesting that compensatory responses become increasingly systematic during the second half of the first year. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

基于增量式PID算法的帆板控制系统的设计

基于STC12C5A60S2单片机与增量式PID算法,实现对帆板系统的控制。该系统主要由键盘模块、显示模块、风扇驱动模块、角度测量模块、报警模块组成。角度传感器测量帆板的角度并反馈回单片机,通过增量式PID算法计算,并由PWM方法控制风扇的转速,从而实现精确控制风扇风力与帆板角度。     

HTML5在移动互联网中的应用

随着移动通信技术的革新及互联网产业的迅猛发展,以移动互联网为代表的移动数据业务呈现出快速增长的势头,HTML5的出现给移动互联网带来了新的变革。本文首先介绍了移动互联网的发展现状、业务模式,HTML5的发展与技术特点,然后对HTML5在移动互联网中的应用进行了阐述,并列举了部分案例。     

纯电动汽车太阳能辅助空调控制系统的硬件设计

纯电动汽车车载动力电池是其唯一的动力源且很有限,辅助设备消耗的电能减少了纯电动汽车的续驶里程,尤其是空调,所以开发高效的纯电动汽车空调系统是纯电动汽车能够被市场接受的关键。将纯电动汽车顶盖布满太阳电池,可以使空调系统的制冷能力增强,同时还能增加纯电动汽车的行驶距离。对小型纯电动汽车的太阳能辅助空调系统进行研究,设计出适合该空调的自动控制系统,可为纯电动汽车创造出一个更加舒适的驾驶和乘座环境。     

铸态及快淬态无钴AB5型贮氢合金的循环稳定性

对AB5型LaxMm1-x(NiMnSiAlFe)49(x=0,0.45,0.75,1.00,摩尔分数)贮氢合金进行了快淬处理,研究了La含量及快淬工艺对合金微观结构及电化学循环稳定性的影响.结果表明:La含量的增加对铸态合金的循环稳定性没有明显影响,但使快淬态合金的循环稳定性下降,且快淬处理能显著提高合金的循环稳定性.当La替代量从0增加到1.00时,经300次充放循环后,铸态合金的容量保持率(Rh)从59.2%增加到59.8%;16 m/s淬速快淬态合金的容量保持率从83.9%下降到65.0%.对于x=0.45的合金,当淬速从0(铸态被定义为淬速等于0)增加到28 m/s时,容量保持率从59.8%增加到75.8%.     

Molecular Mechanisms and Tumor Biological Aspects of 5-Fluorouracil Resistance in HCT116 Human Colorectal Cancer Cells

5-Fluorouracil (5-FU) is a cornerstone drug used in the treatment of colorectal cancer (CRC). However, the development of resistance to 5-FU and its analogs remain an unsolved problem in CRC treatment. In this study, we investigated the molecular mechanisms and tumor biological aspects of 5-FU resistance in CRC HCT116 cells. We established an acquired 5-FU-resistant cell line, HCT116R^F10. HCT116R^F10 cells were cross-resistant to the 5-FU analog, fluorodeoxyuridine. In contrast, HCT116R^F10 cells were collaterally sensitive to SN-38 and CDDP compared with the parental HCT16 cells. Whole-exome sequencing revealed that a cluster of genes associated with the 5-FU metabolic pathway were not significantly mutated in HCT116 or HCT116R^F10 cells. Interestingly, HCT116R^F10 cells were regulated by the function of thymidylate synthase (TS), a 5-FU active metabolite 5-fluorodeoxyuridine monophosphate (FdUMP) inhibiting enzyme. Half of the TS was in an active form, whereas the other half was in an inactive form. This finding indicates that 5-FU-resistant cells exhibited increased TS expression, and the TS enzyme is used to trap FdUMP, resulting in resistance to 5-FU and its analogs.     

The GNAQ T96S Mutation Affects Cell Signaling and Enhances the Oncogenic Properties of Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC), the most common malignant tumor in the liver, grows and metastasizes rapidly. Despite advances in treatment modalities, the five-year survival rate of HCC remains less than 30%. We sought genetic mutations that may affect the oncogenic properties of HCC, using The Cancer Genome Atlas (TCGA) data analysis. We found that the GNAQ T96S mutation (threonine 96 to serine alteration of the Gαq protein) was present in 12 out of 373 HCC patients (3.2%). To examine the effect of the GNAQ T96S mutation on HCC, we transfected the SK-Hep-1 cell line with the wild-type or the mutant GNAQ T96S expression vector. Transfection with the wild-type GNAQ expression vector enhanced anchorage-independent growth, migration, and the MAPK pathways in the SK-Hep-1 cells compared to control vector transfection. Moreover, cell proliferation, anchorage-independent growth, migration, and the MAPK pathways were further enhanced in the SK-Hep-1 cells transfected with the GNAQ T96S expression vector compared to the wild-type GNAQ-transfected cells. In silico structural analysis shows that the substitution of the GNAQ amino acid threonine 96 with a serine may destabilize the interaction between the regulator of G protein signaling (RGS) protein and GNAQ. This may reduce the inhibitory effect of RGS on GNAQ signaling, enhancing the GNAQ signaling pathway. Single nucleotide polymorphism (SNP) genotyping analysis for Korean HCC patients shows that the GNAQ T96S mutation was found in only one of the 456 patients (0.22%). Our data suggest that the GNAQ T96S hotspot mutation may play an oncogenic role in HCC by potentiating the GNAQ signal transduction pathway.     

5G无线通信基站共享电力杆塔的应用研究

将5G无线通信基站安装在电力线杆塔上,可以通过电力线路杆塔共享促进5G网络建设,实现电力企业和通信公司的互利共赢。重点讨论了5G基站的新架构,分析了把基站应用到电力杆塔上应考虑的供电、接地、安装等问题,并给出了相应的解决方案。