Alternatives to standard hemodialysis

Survival of patients on hemodialysis remains poor, but the benefits of increasing urea clearance have probably been maximized within our current treatment schedules. Long dialysis sessions (8 hr) produce impressive outcomes, with mortality 53% to 55% lower than conventional schedules. Even increasing from 4 to 5 hr may improve survival. Increased frequency of dialysis (6 times weekly) produces impressive reductions in left ventricular mass and could conceivably be implemented in‐center. Preliminary data suggest a 61% reduction in mortality with increased frequency. Nightly dialysis combines longer sessions with increased frequency and has produced remarkable clinical gains in blood pressure, left ventricular mass, serum phosphate, and sleep apnea. However, the data are mainly from case series and impact on mortality remains unknown. Expansion of home hemodialysis would be necessary for this modality to grow. Convective therapies remove middle molecules more effectively, and observational data suggest hemodiafiltration has the potential to improve mortality by 35% to 36%. Hemodiafiltration has the advantage of being relatively easy to implement. The uremic milieu is complex and further investigation of the underlying pathophysiology is needed to inform future dialysis interventions. The survival data above are from observational studies, and hence benefits are likely to be exaggerated. Randomized trials of dialysis interventions are desperately needed. They remain difficult to perform, because of the complexity of both the patient population and the interventions, and because of limited available funding.     

Risk Factors for Course of Posttraumatic Stress Disorder Among Vietnam Veterans: A 14-Year Follow-Up of American Legionnaires.

Risk factors affecting the course of posttraumatic stress disorder (PTSD) are poorly understood. As part of a larger study on characterizing exposure to herbicides in Vietnam, the authors investigated this issue in a random sample of 1,377 American Legionnaires who had served in Southeast Asia during the Vietnam War and were followed over a 14-year period. High combat exposure, perceived negative community attitudes at homecoming, minority race, depression symptoms at Time 1, and more anger at Time 1 predicted a more chronic course. Community involvement at Time 1 was protective and associated with decreased risk at Time 2. Discomfort in disclosing Vietnam experiences was associated with an increased risk for developing PTSD but did not predict its course. Combat exposure predicted PTSD course more strongly than any other risk factor. Findings suggest recovery from PTSD is significantly influenced by perceived social support. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

水热合成纳米氧化锡粉体工艺因素研究

以SnCl4·5H2O和氨水为原料,通过正交实验并借助于XRD、TEM等手段,研究了前驱物浓度、反应温度、保温时间和氨水滴加速率等工艺因素对水热合成纳米SnO2粉体的影响。     

A Profile of Psychologists' Views of Critical Risk Factors for Completed Suicide in Older Adults.

The ability to accurately and reliably predict whether an older adult will commit suicide has eluded clinicians and researchers. A random national sample of psychologists who work with older adults was surveyed regarding their perception of 36 risk factors for completed suicide and indirect self-destructive behavior in older adults. This study produced a profile of psychologists' assessment and treatment practices when working with suicidal older adults. Determining what psychologists consider to be the most salient risk factors for completed suicide is important in identifying a minimum standard that clinicians should follow when assessing older adults. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

76 mm口径EFP成形过程数值模拟及影响因素研究

采用LS-DYNA3D对76mm口径药型罩爆炸成型弹丸(EFP)的成形过程进行了数值模拟，模拟结果与实验数据基本吻合．通过数值模拟着重分析了装药长径比L／D、壳体厚度、药型罩壁厚对EFP速度的影响规律，得到了有关EFP成形速度公式，得出EFP速度随L／D的增大而增大，随药型罩厚度增大而减小，受装药外壳厚度影响不大．     

Parental Problem Drinking and Children's Adjustment: Attachment and Family Functioning as Moderators and Mediators of Risk.

Children's perceived attachments with parents, and family cohesion and adaptability were examined as predictors, mediators, and moderators in the parental problem drinking-child outcomes link. A total of 216 6- to 12-year-olds (110 boys, 106 girls) participated. Data were obtained from children and their mothers, fathers, and teachers. A higher level of family cohesion and adaptability functioned as (a) a robust protective factor against adjustment and cognitive difficulties otherwise associated with problem drinking and (b) a mediator of adjustment problems. Children's perceptions of attachments to mothers and fathers were consistent predictors of behavioral, social, and cognitive problems and further moderated relations between problem drinking and child functioning. The results support that child-parent and family functioning variables act as either pathways and/or vulnerability and protective factors for children exposed to a high-risk environment. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

论大学生体育参与动机的培养

大学生具有良好的参与动机是实现体育教学目标的一个重要前提条件。本文通过对体育参与动机内涵及影响体育参与动机的心理因素的分析，提出了大学体育教学中如何培养大学生正确的体育参与动机的一些想法，以供广大体育工作者参考。     

Acculturation, Familism, Parental Monitoring, and Knowledge as Predictors of Marijuana and Inhalant Use in Adolescents.

The authors investigated relationships between marijuana and inhalant use and several cultural and demographic factors in Anglo American and Hispanic American adolescents (N=1,094). Outcome measures assessed lifetime and 30-day marijuana and inhalant use. Predictors and covariates used in logistic regression analyses were region, grade, gender, knowledge, acculturation, familism, and parental monitoring. Hispanic Americans exhibited higher usage across all measures. In this group, high acculturation was associated with low marijuana, but high inhalant, use. Across all participants, positive family relations and parental monitoring were strongly associated with attenuated marijuana use hut only among those most knowledgeable about drugs. Familism and monitoring were not associated with diminished usage among the less knowledgeable. For inhalants, monitoring combined with high knowledge or high familism was associated with diminished usage. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

On integral equation approaches to the mechanics of fibre-crack interaction

The paper examines the problem of a penny-shaped crack which is formed by the development of a crack in both the fibre and the matrix of a composite consisting of an isolated elastic fibre located in an elastic matrix of infinite extent. The composite region is subjected to a uniform strain field in the direction of the fibre. The paper presents two integral-equation based approaches for the analysis of the problem. The first approach considers the formulation of the complete integral equations governing the associated elasticity problem for a two material region. The second approach considers the boundary integral equation formulation of the problem. Both methods entail the numerical solution of the governing integral equations. The solutions to these integral equations are used to evaluate the stress intensity factor at the boundary of the penny-shaped crack.     

Results of the ASTM field test of tristimulus weighting functions

In 1993, the American Society for Testing and Materials carried out a field test of newly calculated tristimulus weighting factors. These weighting factors had been calculated by a method proposed by Venable. the test also included a method of correction for bandpass dependence put forth by Stearns. the purpose of the trial was to assess the possible reduction in bandpass dependence introduced by each of these sets of weights. A large number of sets of spectral data were gathered from the cooperators in the field test. Results of integration by the various sets of tristimulus weighting factors were calculated. A total of 15 120 color differences were calculated and statistics were derived to test the probable error resulting from each method of correction. Errors attributable to bandpass dependence were on the order of a few tenths to as much as one CIELAB unit when uncorrected weight sets were used. These errors could be reduced to a few hundreths of a CIELAB unit, and in some cases to a few thousandths of a unit, by employing one correcting strategy or the other. an overall mix of strategies was ultimately chosen to minimize the bandpass dependence over the entire range of weight sets. Utilizing this mixed strategy, the median error introduced into 10-nm integration by bandpass dependence was only 0.004 CIELAB units. © 1995 John Wiley & Sons, Inc.