Data quality assessment: The Hybrid Approach

Various techniques have been proposed to enable organisations to assess the current quality level of their data. Unfortunately, organisations have many different requirements related to data quality (DQ) assessment. For example, some organisations may need to focus on ensuring regulations are met rather than reducing costs. Due to this, organisations may be forced to follow an assessment technique, which may not wholly fit their needs and current situation. Therefore, we propose and evaluate the Hybrid Approach to assessing DQ, which demonstrates how to dynamically configure an assessment technique as needed while leveraging the best practices from existing assessment techniques.     

Role of phosphoproteomics in the development of personalized cancer therapies

Cell signalling pathways driven by protein and lipid kinases contribute to the onset and progression of virtually all cancer types. Consequently, several inhibitors against these enzymes have clinical utility for the treatment of different forms of cancer. A problem that hampers further development is that not all patients respond equally well to kinase inhibitors and a significant proportion of those that initially respond eventually develop resistance. This review considers how an integrative analysis of kinase signalling may be used to address this issue. Advances in the biophysics of mass spectrometry, in biochemical procedures for phosphopeptide enrichment, and in computational approaches for label-free quantification have contributed to the development of phosphoproteomics workflows compatible with the analysis of clinical material. These developments, together with new bioinformatics tools to derive information on signalling circuitry from phosphoproteomics data, allow investigating kinase networks with unprecedented depth. Phosphoproteomics technology is starting to be used in translational research and, with further developments, such methods may also be able to measure the circuitry of cancer signalling networks in routine clinical assays. This review reflects on how this information could be used to accurately predict the best kinase inhibitor for each individual cancer patient.     

产、学、研三结合办学刍议

本文总结了产、学、研三结合办学模式的实践,论述了三结合办学模式的结合点与相互关系,指出了三结合办学模式是高工专培养应用型人材的有效方．     

坐标变换方法在零部件检验中的运用

简介在万能工具显微镜上,运用坐标系旋转方法测量零件形状、位置的原理、方法以及仪器操作技巧。     

掺BaTiO3对（1-x）NBT—xBaTiO3系陶瓷材料的铁电牲能的影响

采用RadiantPrecisionWorkstation铁电测试系统测试样品的铁电性能,分析BaTiO3的掺人对（1-x）NBT—xBaTiO3系陶瓷材料的铁电性能的影响。实验结果表明：Ba2＋的掺入可有效地降低NBT基陶瓷的剩余极化强度和矫顽场,在准同型相界组成点,矫顽场达到最小值。     

可逆式双机架冷轧轧机系统中卷径的测量及计算

本文介绍了轧钢厂砹机架可逆冷轧轧机控制系统对卷径的测量和计算方法，该方法控制精度比较高，较好的满足系统控制的要求。     

三峡-葛洲坝梯级水库调度对坝下河流的生态水文影响

本文以1901-2002年宜昌水文站日流量作为三峡水库的入库流量,模拟三峡-葛洲坝梯级水库正常运行后的泄流过程,采用水文变化指标法和变化范围法,评估调度对葛洲坝下游河流33项生态水文指标的影响.研究表明:梯级水库运行将坝下河流月均流量在10月份显著降低、5月和6月上旬明显增加、1～3月份普遍增至5000m3/s左右;年...     

求相量模的一种新的近似方法

提出了一种新的求相量模值的近似方法，与其它方法相比，该算法具有比较高的近似精度，四分区时，最大误差小于７．８７５×１０－３％，在微机保护和控制装置中具有较高的实用价值。     

频率选择表面电磁仿真

文中采用谱域法对频率选择表面(Frequency Selective Surfaces)进行仿真,谱域法是与矩量法结合在一起的.谱域法与国内常用的模式匹配法相比能仿真具有更复杂形状的FSS单元,且在计算多个介质夹层中的FSS计算量小,并能得出非常理想的仿真结果并用于设计.本文采用这种方法得到的结果与实测结果相吻合.     

高精度直流测速发电机输出交流量中的2p次和4p次谐波分析

本文对直流测速发电机精度测试中输出电压纹波进行了理论分析,并通过对由于电枢偏心和铁心呈椭圆引起的纹波进行数学分析,证明电枢偏心将产生2p次谐波,电枢铁心呈椭圆将产生4p次谐波。文章最后对减少输出电压纹波的方法进行了探讨。