甲型肝炎病毒(L-A-1株)基因型分析

目的 分析甲肝病毒基因型,为确定我国甲肝的分子流行病学及疫苗的安全性和免疫原性奠定基础。方法 采用抗原捕获聚合酶链反应（AC/PCR）,依据国际上甲肝病毒分型标准,扩增VP1/2A结合处的168个核苦酸（nt2909～3264）。结果 经生物信息学软件分析,得出L-A-1株病毒属于甲肝病毒基因IB亚型。结论 在我国有IA和IB两个亚型甲肝病毒流行。     

复分解四步循环法制取硫酸钾新工艺

介绍了制取硫酸钾的一种新工艺－－复分解四步循环法，即氯化钾与硫酸铵反应生成硫酸钾铵与氯化铵钾，硫酸钾铵再与氯化钾溶液反应生成硫酸钾，氯化铵钾再与硫酸铵溶液反应生成氯化铵。整个工艺全封闭循环生产，产品硫酸钾K2O质量分数≥50％，钾收率达92％。     

3-氯-4-（2-溴甲基-4-甲基-1，3-二恶戍烷-2-基）苯基-4’-氯苯基醚的合成

3-氯-4-（2-溴甲基-4-甲基-1，3-二恶戍烷-2-基）苯基-4’-氯苯基醚是杀菌剂苯醚甲环唑的一个重要中间体。以2-氯-4-（4-氯苯氧基）-苯乙酮为起始原料，采用溴化和合环同时进行的合成工艺制得该化合物，收率90％．产品含量95％。优化了反应条件，简化了操作。     

Distributed receding horizon control of large-scale nonlinear systems: Handling communication delays and disturbances

This paper studies the robust distributed receding horizon control (DRHC) problem for large-scale continuous-time nonlinear systems subject to communication delays and external disturbances. A dual-mode robust DRHC strategy is designed to deal with the communication delays and the external disturbances simultaneously. The feasibility of the proposed DRHC and the stability of the closed-loop system are analyzed, and the sufficient conditions for ensuring the feasibility and stability are developed, respectively. We show that: (1) the feasibility is affected by the bounds of external disturbances, the sampling period and the bound of communication delays; (2) the stability is related to the bounds of external disturbances, the sampling period, the bound of communication delays and the minimum eigenvalues of the cooperation matrices; (3) the closed-loop system is stabilized into a robust invariant set under the proposed conditions. A simulation study is conducted to verify the theoretical results.     

Stability analysis of bilinear systems under aperiodic sampled-data control

This note considers the problem of local stability of bilinear systems with aperiodic sampled-data linear state feedback control. The sampling intervals are time-varying and upper bounded. It is shown that the feasibility of some linear matrix inequalities (LMIs), implies the local asymptotic stability of the sampled-data system in an ellipsoidal region containing the equilibrium. The method is based on the analysis of contractive invariant sets, and it is inspired by the dissipativity theory. The results are illustrated by means of numerical examples.     

Static output feedback control via PDE boundary and ODE measurements in linear cascaded ODE–beam systems

This paper addresses the problem of feedback control design for a class of linear cascaded ordinary differential equation (ODE)–partial differential equation (PDE) systems via a boundary interconnection, where the ODE system is linear time-invariant and the PDE system is described by an Euler–Bernoulli beam (EBB) equation with variable coefficients. The objective of this paper is to design a static output feedback (SOF) controller via EBB boundary and ODE measurements such that the resulting closed-loop cascaded system is exponentially stable. The Lyapunov’s direct method is employed to derive the stabilization condition for the cascaded ODE–beam system, which is provided in terms of a set of bilinear matrix inequalities (BMIs). Furthermore, in order to compute the gain matrices of SOF controllers, a two-step procedure is presented to solve the BMI feasibility problem via the existing linear matrix inequality (LMI) optimization techniques. Finally, the numerical simulation is given to illustrate the effectiveness of the proposed design method.     

Event-driven observer-based output feedback control for linear systems

This paper concerns the problem of event-driven observer-based output feedback control of linear systems. Contrary to normal sampled-data control systems, where the controller is updated periodically, in event-driven systems, it is updated only when an “event” happens, and a typical event is defined as some error signals exceeding a given threshold. Both continuous- and discrete-time event detector cases are considered. It is shown that even with the significantly reduced sampling frequency, the global uniform ultimate boundedness of the event-driven closed-loop systems can also be guaranteed. A numerical example is finally used to illustrate the effectiveness and advantages of the proposed approaches.     

Motion-based method for estimating time required to attach self-adhesive insulators

A self-adhesive insulator is a component of a home appliance that is used to suppress vibration or prevent humidity affecting the internal parts of the appliance. There is a wide range of types and designs available, allowing them to be applied to areas having different shapes. At the design stage, once an insulator design has been developed sufficiently to identify its dimensions and features, the attaching time and baseline cost must be estimated with reasonable accuracy to enable a comparison of vendor quotes. However, the current estimation method is not sufficiently accurate in terms of the baseline cost. This paper presents a motion-based time-estimating scheme with which the time required for the attachment of such insulators can be calculated more accurately. The scheme has been developed by analyzing the motions needed to attach 350 insulators and then designating representative motions and their time values. For this purpose, a modular arrangement of predetermined time standards (MODAPTS) is adopted. Motion-based time-estimation method is useful in terms of simplicity and accuracy. It enables design engineers to estimate the time required for the attachment based only on a drawing of the insulator and a few MODAPTS rules. Estimates made with this method should vary from the actual value by no more than 9.5%.     

Posture variation among office workers when using different information and communication technologies at work and away from work

Office workers perform tasks using different information and communication technologies (ICT) involving various postures. Adequate variation in postures and muscle activity is generally believed to protect against musculoskeletal complaints, but insufficient information exists regarding the effect on postural variation of using different ICT. Thus, this study among office workers aimed to determine and compare postures and postural variation associated with using distinct types of ICT. Upper arm, head and trunk postures of 24 office workers were measured with the Physiometer® over a whole day in their natural work and away-from-work environments. Postural variation was quantified using two indices: APDF_(90-10) and EVA_(sd). Various ICT had different postural means and variation. Paper-based tasks had more non-neutral, yet also more variable postures. Electronics-based tasks had more neutral postures, with less postural variability. Tasks simultaneously using paper- and electronics-based ICT had least neutral and least variable postures. Tasks without ICT usually had the most posture variability. Interspersing tasks involving different ICT could increase overall exposure variation among office workers and may thus contribute to musculoskeletal risk reduction.