The role of coping in the relationship between perceived racism and racism-related stress for Asian Americans: Gender differences.

On the basis of stress and coping theory, the authors examined coping as a mediator of the relationship between perceptions of racism and racism-related stress with a sample of Asian American college students (N = 336). Results indicated that coping mediated the relationship between racism and racism-related stress differentially by gender. The more that men perceived racism, the more likely they were to use support-seeking coping strategies that were associated with higher levels of racism-related stress. The more that women perceived racism, the more they used active coping strategies that were associated with higher levels of racism-related stress. The findings demonstrate how coping with racism differs for Asian Americans on the basis of gender. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

数字化核电厂班组SSA测度方法与实验研究

情景意识(SA)问题在数字化核电厂中更为突出。为识别班组共享情景意识（SSA）水平及行为形成因子（PSF）对班组SSA的影响,基于情景意识全面评估技术（SAGAT）建立一种班组SSA测量和计算方法并进行模拟机实验。结果表明,个体SA（ISA）水平与SSA水平有关,ISA级别越高,SSA级别越高;ISA和班组SSA都受到PSF的影响,PSF的状态水平越高,ISA和SSA的水平越高;对于不同的实验场景,操纵员的ISA水平和班组SSA水平不同,这表明风险场景的症状越明显及知识经验水平越好,ISA和SSA水平就越高。最后,通过被试的自评价识别当前PSF的状态水平,主要不良的PSF是班组沟通和合作水平、压力水平、人-机界面等。这些评估结果为提高数字化核电厂人因可靠性和安全水平提供了理论支持。     

Structure factors of modified liquid Al–Si alloys

The structure factor and the coordination numbers of liquid Al–Si alloys with different Si content have been measured by a high temperature X-ray diffractometer. Radial distribution functions (RDFs), the nearest atomic distance and the coordination numbers of eutectic Al–Si alloys before and after being modified with Sr and Sb were studied. The RDFs of the liquid alloy were decomposed by five Gaussian peaks. The results show that a Si–Si covalent bond exists in the liquid of eutectic and hyper-eutectic alloys. Sr in the liquid Al–Si has a capability to weaken the covalent bonds of Si–Si, suppressing the nucleation of the eutectic silicon phase. On the other hand, Sb in the liquid Al–Si increases the order degree of Si atoms, decreasing the supercooling degree of the nucleation and promoting the nucleation of eutectic silicon.     

Maximum-likelihood mixture factor analysis model and its application for process monitoring

In the present paper, a mixture form of the factor analysis model is developed under the maximum-likelihood framework. In this new model structure, different noise levels of process variables have been considered. Afterward, the developed mixture factor analysis model is utilized for process monitoring. To enhance the monitoring performance, a soft combination strategy is then proposed to integrate different local monitoring results into a single monitoring chart, which is based on the Bayesian inference method. To test the modeling and monitoring performance of the proposed mixture factor analysis method, a numerical example and the Tennessee Eastman (TE) benchmark case studies are provided.     

Stress intensity factor computation using the method of fundamental solutions: mixed‐mode problems

The method of fundamental solutions is applied to the computation of stress intensity factors in linear elastic fracture mechanics. The displacements are approximated by linear combinations of the fundamental solutions of the Cauchy–Navier equations of elasticity and the leading terms for the displacement near the crack tip. Two algorithms are developed, one using a single domain and one using domain decomposition. Numerical results are given. Copyright © 2006 John Wiley & Sons, Ltd.     

Self-Renewal and Cancers of the Gastric Epithelium: An Update and the Role of the Lectin TFF1 as an Antral Tumor Suppressor

In 2020, gastric cancer was the fourth leading cause of cancer deaths globally. About 90% of gastric cancers are sporadic and the vast majority are correlated with Helicobacter pylori infection; whereas familial clustering is observed in about 10% of cases. Gastric cancer is now considered to be a disease originating from dysregulated self-renewal of the gastric glands in the setting of an inflammatory environment. The human stomach contains two types of gastric units, which show bi-directional self-renewal from a complex variety of stem cells. This review focuses on recent progress concerning the characterization of the different stem cell populations and the mainly mesenchymal signals triggering their stepwise differentiation as well as the genesis of pre-cancerous lesions and carcinogenesis. Furthermore, a model is presented (Lectin-triggered Receptor Blocking Hypothesis) explaining the role of the lectin TFF1 as an antral tumor suppressor possibly regulating Lgr5⁺ antral stem cells in a paracrine or maybe autocrine fashion, with neighboring antral gland cells having a role as niche cells.     

Development and Characterization of a Factor V-Deficient CRISPR Cell Model for the Correction of Mutations

Factor V deficiency, an ultra-rare congenital coagulopathy, is characterized by bleeding episodes that may be more or less intense as a function of the levels of coagulation factor activity present in plasma. Fresh-frozen plasma, often used to treat patients with factor V deficiency, is a scarcely effective palliative therapy with no specificity to the disease. CRISPR/Cas9-mediated gene editing, following precise deletion by non-homologous end-joining, has proven to be highly effective for modeling on a HepG2 cell line a mutation similar to the one detected in the factor V-deficient patient analyzed in this study, thus simulating the pathological phenotype. Additional CRISPR/Cas9-driven non-homologous end-joining precision deletion steps allowed correction of 41% of the factor V gene mutated cells, giving rise to a newly developed functional protein. Taking into account the plasma concentrations corresponding to the different levels of severity of factor V deficiency, it may be argued that the correction achieved in this study could, in ideal conditions, be sufficient to turn a severe phenotype into a mild or asymptomatic one.     

Analysis of non-loading carrying fillet welds joint using SGBEM

Fatigue failure is probably the most common type of failure in welded construction. It is usually initiates at a stress concentration area within the structure. The fatigue behavior of non-load carrying cruciform fillet welded joint has been studied extensively using boundary element method. The symmetric boundary element method for multiple cracks problem is derived using Betti's reciprocal theorem in auxiliary fictitious state. High order element is proposed to solve the double integrals. The analysis demonstrates that symmetrical Galerkin boundary element method (SGBEM) can be used effectively for analyzing non-load carrying fillet welded cruciform joints containing any number of surface and embedded cracks. The stress intensity factor and the magnification factors M _k are analyzed. General formulation for this kind of fatigue life estimation is derived for engineering design purpose. The fatigue life estimate results are consistent with the code of practice and those of other researchers. This can provide a good method for engineering design under fatigue loading conditions.     

Dempster-Shafer证据理论在目标意图预测中的应用

为了准确对目标意图进行预测,以便我方及时合理地作出战术决策,采用D-S证据理论对目标意图进行预测。首先提取出影响目标意图预测的各个态势因素,然后分析每个因素的影响效果。在此基础上建立目标意图预测的数学模型,利用D-S合成法则将所有因素的影响进行综合,并计算出各个可能命题的概率赋值并给出相应决策。最后,通过仿真实例验证了该方法在目标意图预测中的可行性和实用性。     

基于文本挖掘的WUI火灾致灾因子网络构建及特征分析

为预防和减少WUI火灾的发生, 挖掘WUI火灾关键致灾因子, 厘清致灾因子间的作用机制. 本文首先基于本文挖掘技术从WUI火灾事故案例中得到致灾因子, 使用Apriori算法得到致灾因子之间的关联规则. 然后使用复杂网络理论构建WUI火灾致灾因子网络, 计算网络拓扑特征参数, 探析WUI火灾致灾因子网络特征. 最后引入WUI火灾致因链风险度指标, 挖掘出高风险连边, 并提出断链措施. 结果表明: WUI火灾致灾因子网络具有小世界特性, 高温、强风、干旱等对其他致灾因子影响较大. 燃烧废弃物、植物起火、应急响应速度、人为纵火、强风在不同致灾因子转换中具有重要作用, 应加强管控. 网络中风险度最高的边是燃烧废弃物→植物起火, 通过颁布禁止擅自燃烧废弃物等规定, 即可切断该风险链, 实现对WUI火灾的预防和主动控制.