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An obnoxious facility is to be located inside a polygonal region of the plane, maximizing the sum of the k smallest weighted Euclidean distances to n given points, each protected by some polygonal forbidden region. For the unweighted case and k fixed an O(n2logn) time algorithm is presented. For the weighted case a thorough study of the relevant structure of the multiplicatively weighted order-k-Voronoi diagram leads to the design of an O(kn3+n3logn) time algorithm for finding an optimal solution to the anti-t-centrum problem for every t=1,…,k, simultaneously. 相似文献
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根据成缆生产线的工艺要求,提出了一种基于S7-300 PLC和现场总线的3150型盘绞成缆机控制系统的设计方案,给出了3150型盘绞成缆机的整体结构,详细介绍了系统硬件及软件设计,并给出了盘绞头与放线架的同步控制方法。实际应用表明,该系统结构简单、使用灵活方便、控制精度高、人机对话良好,达到了预期目标。 相似文献
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In this paper, by constructing various kinds of sub- and super-solutions and using the basic properties of M-matrix, we give the necessary and sufficient conditions of global existence for nonnegative solutions to a degenerate parabolic system with completely coupled boundary conditions, which generalize the recent results of, for instance, Cui [Z. Cui, Critical curves of the non-Newtonian polytropic filtration equations coupled with nonlinear boundary conditions, Nonlinear Anal. 68 (2008) 3201–3208], Zhou–Mu [J. Zhou, C. Mu, Algebraic criteria for global existence or blow-up for a boundary coupled system of nonlinear diffusion equations, Appl. Anal. 86 (2007) 1185–1197] etc. 相似文献
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In this paper, we investigate an inexact hybrid projection-proximal method for solving a class of generalized mixed variational inequalities in Hilbert spaces. We construct a general inexact hybrid projection-proximal point algorithm, in which an inexact relaxed proximal point step is followed by a suitable orthogonal projection onto a hyperplane. Under some suitable conditions concerned with the pseudomonotone set-valued mapping T, the nonsmooth convex function f and the step size λk, we prove the convergence of the inexact hybrid projection-proximal point algorithm for solving generalized mixed variational inequalities in Hilbert spaces. 相似文献
100.
Purpose : Zilongjin, a complementary Chinese herbal medicine, has been used to alleviate the adverse effects of chemotherapeutic drugs in cancer therapy. However, the mechanisms of anti‐cancer activity of Zilongjin are still largely unkonwn. Experimental design : First, the proteomic approach of combined 2‐DE and ESI‐MS/MS was used to investigate the effect of Zilongjin on the protein expression in MCF‐7 cells. Then, the differential expression of some proteins was confirmed by Western blot, cytoimmunofluoresecnce, and quantitative real‐time RT‐PCR analysis. Results : The identified proteins with differential expression, involved in such events as protein translation, cellular signal transduction, cytoskeleton formation and transportation, include seven downregulating proteins, such as Eukaryotic translation initiation factor 3 subunit I, Eukaryotic translation initiation factor 1A Y‐chromosomal, Ran‐specific GTPase‐activating protein, Ubiquitin‐conjugating enzyme E2 N, Tropomodulin‐3, Macrophage‐capping protein, and Tumor protein D52, as well as two upregulating proteins, HSP β‐1 and keratin18. Moreover, the differential expression of three proteins was confirmed. Conclusions and clinical relevance : (i) These results provide a new insight into the molecular mechanisms of Zilongjin on therapy for breast cancer. (ii) The application of the proteomic approaches will result in the more extended appreciation of Chinese medicine than those known at present. 相似文献