基于PCS7的全液压矫直机监控系统

介绍了PCS7软件在四重式全液压可逆十一辊矫直机控制系统中的应用,以及一个包含了自动化站、主操作站、监控站、工程师站等的分布式计算机控制系统。该系统通过PLC控制变频器,实现传动电机速度控制,以及通过液压调整位置控制回路,实现板材矫直中辊缝位置的设定与恒定保持;这样矫直的钢板,头尾均得到很好的矫直质量。     

Input-output properties of the Page-Hinkley detector

We consider the stochastic input-output properties of a simple non-linear dynamical system, the so-called Page-Hinkley detector, playing a key role in change detection, and also in queuing theory. We show that for L-mixing inputs with negative expectation the output process of this system is L-mixing. The result is applied to get an upper bound for the false alarm rate. The proof is then adapted to get a similar result for the case of random i.i.d. inputs. Possible extensions and open problems are given in the discussion.     

Design of experiments for bivariate binary responses modelled by Copula functions

Optimal design for generalized linear models has primarily focused on univariate data. Often experiments are performed that have multiple dependent responses described by regression type models, and it is of interest and of value to design the experiment for all these responses. This requires a multivariate distribution underlying a pre-chosen model for the data. Here, we consider the design of experiments for bivariate binary data which are dependent. We explore Copula functions which provide a rich and flexible class of structures to derive joint distributions for bivariate binary data. We present methods for deriving optimal experimental designs for dependent bivariate binary data using Copulas, and demonstrate that, by including the dependence between responses in the design process, more efficient parameter estimates are obtained than by the usual practice of simply designing for a single variable only. Further, we investigate the robustness of designs with respect to initial parameter estimates and Copula function, and also show the performance of compound criteria within this bivariate binary setting.     

高铁接触网异物侵入的机器视觉检测方法

接触网是沿铁路线上空架设的为电力机车供电的输电线路,接触网上附着的鸟巢等异物将对列车运行造成安全隐患。目前主要是通过人工检查的方式对接触网异物进行检测并清除,这种方式不仅成本高,效率低,往往不能及时排除安全隐患。为了对接触网异物进行及时有效的检测,同时降低人力成本,针对高铁运行环境的固定结构化特征,综合运用计算机视觉、深度学习等技术对铁路入侵异物进行实时检测。首先基于LSD直线段检测算法获取鸟巢可能出现的感兴趣区域;其次利用YOLOv3网络在ImageNet上进行训练得到一个预训练权重,并使用人工标注的数据集继续训练网络直到网络收敛;最后使用训练好的网络对感兴趣区域存在的鸟巢进行检测。实验结果表明,最终得到的平均检测精度为0.89,平均检测速度为38?f/s,可以实现对异物目标的准确实时检测。     

A PM7 dynamic residue-ligand interactions energy landscape of the BACE1 inhibitory pathway by hydroxyethylamine compounds. Part I: The flap closure process

BACE1 is an enzyme of scientific interest because it participates in the progression of Alzheimer’s disease. Hydroxyethylamines (HEAs) are a family of compounds which exhibit inhibitory activity toward BACE1 at a nanomolar level, favorable pharmacokinetic properties and oral bioavailability. The first step in the inhibition of BACE1 by HEAs consists of their entrance into the protease active site and the resultant conformational change in the protein, from Apo to closed form. These two conformations differ in the position of an antiparallel loop (called the flap) which covers the entrance to the catalytic site. For BACE1, closure of this flap is vital to its catalytic activity and to inhibition of the enzyme due to the new interactions thereby formed with the ligand. In the present study a dynamic energy landscape of residue-ligand interaction energies (ReLIE) measured for 112 amino acids in the BACE1 active site and its immediate vicinity during the closure of the flap induced by 8 HEAs of different inhibitory power is presented. A total of 6.272 million ReLIE calculations, based on the PM7 semiempirical method, provided a deep and quantitative view of the first step in the inhibition of the aspartyl protease. The information suggests that residues Asp93, Asp289, Thr292, Thr293, Asn294 and Arg296 are anchor points for the ligand, accounting for approximately 45% of the total protein-ligand interaction. Additionally, flap closure improved the BACE1-HEA interaction by around 25%. Furthermore, the inhibitory activity of HEAs could be related to the capacity of these ligands to form said anchor point interactions and maintain them over time: the lack of some of these anchor interactions delayed flap closure or impeded it completely, or even caused the flap to reopen. The methodology employed here could be used as a tool to evaluate future structural modifications which lead to improvements in the favorability and stability of BACE1-HEA ReLIEs, aiding in the design of better inhibitors.     

PLC顺控指令在废渣回收系统中的应用

废渣回收系统的逻辑控制是典型的顺序控制,利用PLC可以简便、准确地实现该控制,以西门子S7-200小型PLC为例,介绍了顺序控制的编程方法和优点.     

一种新型智能气敏传感器的研究与设计

研究并设计了一种新型智能气敏传感器.简要介绍了TiO2气敏元件及气敏机理.将拥有ARM7内核的LPC2131微处理器做为主控制器,实时监测电源电压,实现对温度准确控制,同时测量气敏薄膜的电阻,经元件阻值和气体浓度的校准后,显示被测气体浓度,同时提供一个友好的用户界面,并具备报警功能,实现了气敏传感器智能化,具有动态测量范围大(1～500 MΩ),精确度高(精确度优于0.5%),功耗低、体积小、成本低、可重复利用等特点.     

基于SIEMENS S7-400H平台的罐区自动化系统

介绍了根据罐区自动化的特点,控制系统采用SIEMENS S7-400H容错系统,配合SIEMENS WinCC上位软件,实现罐区的监测、控制、报警、计量及定量收付、与数据共享.     

基于MPEG-7的多媒体信息检索研究

研究了MPEG-7的核心内容和多媒体信息检索的主要技术,并对应用MPEG-7进行多媒体信息检索作了一定的探讨.     

基于嵌入式系统的无线传感器网络节点的设计

研究一种基于嵌入式系统的无线传感器网络节点的设计方案。无线传感器节点使用模块化设计,由基于ARM7微处理器的主控模块和在2.4GHz频带上工作的CC2420芯片无线通信模块构成。详细讨论各部分的工作原理和硬件组成,并给出节点试验程序流程图。