南京国民政府时期社会保险立法背景研究（1927-1937年）

当社会保险这种更为先进的保障方式在西方已经实行了四十多年时,对中国民众来说这还是一个陌生的名词,中国社会保障仍然以传统的社会救济为主。南京国民政府成立以后,在政府、民间以及国际劳工组织的推动下,对社会保险立法进行了初步的尝试。     

有色噪声激发下结构随机振动离散分析方法

本文以线性结构体系在白噪声激发下随机振动离散分析方法为基础,对线性结构体系在有色噪声激发下的随机振动离散分析方法进行了研究。给出均值、均方响应的离散递推式.并为了能在计算机上进行实际运算,给出了实用化计算公式,最后用该方法对一结构进行了实际计算,分析了计算结果。     

基于红外焦平面阵列读出结构的非均匀校正算法

空间固定图案噪声严重影响了红外探测器的成像质量,它主要是由于焦平面阵列上各探测单元对于同一辐照的光电响应不完全一致所造成。另外,多通道图像数据采集电路的非均匀性更加重了这种噪声。本文提出了一种基于红外焦平面阵列读出结构的非均匀校正算法,它将校正过程分成两步。首先利用恒定统计方法滤除由通道放大器引起的固定图案噪声,然后再将处理结果通过改进的神经网络方法,进一步校正由探测器响应而产生的非均匀性。由于该算法是递推进行,并且具有收敛速度快、计算复杂度低等优点,因此易于工程实现。文中详细阐述了算法的基本原理及其流程,并用仿真数据和真实红外数据对算法性能进行验证,取得了较好的效果。     

动态核的形态分解联想算法及抗随机噪声研究

在灰度图像分解算法和动态核形态联想记忆网络的基础上,提出了一种新的联想记忆算法--动态核的形态分解联想算法.该方法显著地提高了联想记忆抗随机噪声的能力,较好地解决了灰度图像在含噪时的联想记忆和识别的问题,从而给出了一种恢复含噪灰度图像的途径,并把该方法推广到了彩色图像的处理.通过实验,验证了该方法的良好性能,取得了理想的结果.     

基于多体动力学的汽轮机振动声辐射机理及传递路径

采用多体动力学方法进行汽轮机机械振动激励源精确分析,在激励源分析结果的基础上研究低频激励下的机组振动响应,并采用声传递向量（Acoustic Transfer Vector,ATV）方法研究汽轮机组表面与外场辐射的声压传递贡献量,从多体动力学的角度并结合流固耦合的方法综合分析汽轮机组振动噪声产生机理并研究噪声典型传递路径。研究结果表明,旋转激励源为汽轮机组的主要振动激励源,在低频段汽轮机组辐射模式为单极子,在中高频段汽轮机组辐射模式为偶极子。由噪声辐射的指向性极坐标图可知,在不同高度处噪声指向性相似,并都在长度方向上取得噪声声压级较大值,具有较强的指向性。计算方法对汽轮机组减振降噪研究具有一定的指导意义。     

Identifying cell-to-cell variability in internalization using flow cytometry

Biological heterogeneity is a primary contributor to the variation observed in experiments that probe dynamical processes, such as the internalization of material by cells. Given that internalization is a critical process by which many therapeutics and viruses reach their intracellular site of action, quantifying cell-to-cell variability in internalization is of high biological interest. Yet, it is common for studies of internalization to neglect cell-to-cell variability. We develop a simple mathematical model of internalization that captures the dynamical behaviour, cell-to-cell variation, and extrinsic noise introduced by flow cytometry. We calibrate our model through a novel distribution-matching approximate Bayesian computation algorithm to flow cytometry data of internalization of anti-transferrin receptor antibody in a human B-cell lymphoblastoid cell line. This approach provides information relating to the region of the parameter space, and consequentially the nature of cell-to-cell variability, that produces model realizations consistent with the experimental data. Given that our approach is agnostic to sample size and signal-to-noise ratio, our modelling framework is broadly applicable to identify biological variability in single-cell data from internalization assays and similar experiments that probe cellular dynamical processes.     

网络环境下高职学生英语自主学习探究

从自主学习的重要性出发,论述了网络环境下学生自主学习的内涵,以及自主探究学习模式的评价标准,从而探究网络环境下提高高职学生自主学习能力的有效途径.     

一种5.0~9.3 GHz低功耗宽带低噪声放大器设计

针对Wi-Fi 6、Wi-Fi 6E(5 GHz、6 GHz)的低功耗、宽带宽等无线局域网(WLAN)设备需求,基于65 nm CMOS工艺设计了一款两级低功耗宽带低噪声放大器(LNA)。电路第一级采用结合互补共源电路的共源共栅结构,通过电感峰化技术和负反馈技术的运用,提高输入跨导,降低噪声,并拓展带宽和提高增益平坦度。第二级在共漏极缓冲器基础上引入辅助放大结构、电感峰化技术,实现抵消第一级共源管的噪声并拓展带宽。电路采用提出的前向衬底自偏置技术,以降低电路对电源电压的依赖,整体电路实现两路电流复用,从而有效降低了功耗。仿真结果表明,在5~9.3 GHz频带内LNA的S21为17.8±0.1 dB,S11小于-9 dB、S22小于-11.9 dB,噪声系数小于1.34 dB。在0.8 V电压下整体电路功耗为5.3 mW。     

基于神经网络的图像来源识别方法比较研究

随着手机等便携式智能电子设备的普及,图像已成为最重要的信息载体之一,在新闻、社交及司法等领域发挥着重要作用.在享用电子图像带来便捷性的同时,图像处理工具给不法分子通过篡改电子图像实施诈骗等犯罪活动提供了可能,识别图像来源、辨别图像真伪已成为遏制和惩罚此类犯罪活动的重要技术手段.该文讨论了神经网络在图像源识别中的应用方法...     

TAS2R38 Bitter Taste Receptor Expression in Chronic Rhinosinusitis with Nasal Polyps: New Data on Polypoid Tissue

Studies have shown differences in TAS2R38 receptor expression in patients with chronic rhinosinusitis (CRS) compared to healthy controls. Known agonists of TAS2R38 stimulate epithelial cells, leading to robust intracellular nitric oxide (NO) production, which damages bacterial membranes, enzymes, and DNA, but also increases ciliary beat frequency. In this study we examined, using qRT-PCR, the expression of TAS2R38 receptor in nasal polyps (NP) of patients with CRS (N = 107) and in inferior turbinate mucosa (ITM) of patients with CRS and controls (N = 39), and confronted it with clinical features and the severity of the disease. The expression was shown in 43 (50.00%) samples of ITM in the study group (N = 107), in 28 (71.79%) in the control group (N = 39) (p = 0.037), and in 43 (46.24%) of NP. There were no differences in levels of the expression in all analyzed tissues. Patients who rated their symptoms at 0–3 showed higher TAS2R38 expression in ITM in comparison to the patients with 8–10 points on the VAS scale (p = 0.020). A noticeable, however not significant, correlation between the TAS2R38 expression in ITM and the Lund–Mackay CT score was shown (p = 0.068; R = −0.28). Patients with coexisting asthma had significantly higher receptor expression in the NP (p = 0.012). Our study is the first to confirm the presence of the TAS2R38 receptor in NP. Expression of the TAS2R38 receptor is reduced in the sinonasal mucosa in patients with more advanced CRS with NP.