基于MCKD和峭度的液压泵故障特征提取

液压泵早期故障信号具有非平稳性、强背景噪声、弱故障特征特点,故障特征难以有效提取。为此,提出基于自相关分析与最大相关峭度解卷积算法的齿轮泵故障特征提取方法,利用MCKD算法对采集信号去噪处理,增强信号中的原始冲击成分,提高信号的信噪比;基于峭度（或峭度绝对值,或峭度平方值）的特征信息提取方法,来度量机械信号的非高斯性程度,以表征机械设备的运行状态信息。试验结果证明：所提方法能够有效提取液压泵故障信号中的特征信息。     

短程脉冲无线信道特性仿真与分析

利用仿真语言对短程脉冲无线信道进行仿真研究。考虑短程脉冲无线传播环境为具有某一密度的随机分布的散射体,在一种理想情况下,信道传播环境表现为一个渗透网格。利用仿真语言仿真短程脉冲无线信道中多径分量的传播轨迹,通过脉冲无线信道的随机模型对短程脉冲无线信道特性进行仿真分析,仿真结果表明：利用该模型对短程脉冲无线信道仿真是有效的。     

4MV静电正离子加速器辐射监测系统

介绍由主控计算机和多个探测通道组成的辐射监测系统,可以对多种辐射的能量、强度、剂量率、剂量及剂量当量进行监测.该系统虽然是为4MV静电正离子加速器辐射监测设计制作的,但同样适用于类似条件的其他场所的辐射监测.     

航空装备保障任务规划系统体系结构研究

航空装备保障任务规划系统,采用基于三层结构的数据管道方法,用MSSQL Server2000作为数据库开发平台,并利用SQL自带的OLAP Server建立大型多维数据库,前台软件选用Delphi7,通过开放式数据接口实现连接。系统由数据源,数据的知识化处理、辅助决策、可视化表达4部分组成,通过建立多维数据库,利用数据库分析工具从大量数据中提取有效信息。     

基于熵相关系数的关联性自动判别方法——COCA

数据库自管理、自调优中查询计划的自动优化是目前的关注热点。为保证优化器估值精度,用统计学方法,给出了一种基于熵相关系数的对字段关联性的自动判别的新算法——COCA。该算法有下列特点：（1）限制少,没有卡方检验的频数限制,卡方检验只有在列联表中至少有80%的格子频数大于5的情况下才可信; （2）结果多,卡方检验（CORDS）只判断字段之间是否有关联,新方法可计算字段之间双向的关联程度。实验表明, 新方法更坚固,产生更多的统计信息,可以支持后面更高效、准确地建立直方图。     

Nakagami衰落信道上组合SC/MRC的性能分析

研究Nakagami衰落信道上组合发射机选择合并(SC)/接收机最大比合并(MRC)天线分集系统的性能.使用矩生成函数方法,推导采用组合SC/MRC天线分集和相干检测的MPSK(M进制相移键控)、MQAM(M进制正交幅度调制)、MPAM(M进制脉冲幅度调制)、BFSK(二进制频移键控)、最小相关BFSK(BFSKmin)、差分编码BPSK(DE-BPSK)和预编码MSK(最小频移键控)等几种M进制数字调制方式在Nakagami衰落信道上的误符号率性能,获得了M进制数字调制系统误符号率性能的精确数学表达式.数值计算结果阐明了发射天线和接收天线数目以及衰落参数对数字调制系统误符号率性能的影响.     

Cation Permeability of Voltage-Gated Hair Cell Ca2+ Channels of the Vertebrate Labyrinth

Some hearing, vestibular, and vision disorders are imputable to voltage-gated Ca²⁺ channels of the sensory cells. These channels convey a large Ca²⁺ influx despite extracellular Na⁺ being 70-fold more concentrated than Ca²⁺; such high selectivity is lost in low Ca²⁺, and Na⁺ can permeate. Since the permeation properties and molecular identity of sensory Ca²⁺ channels are debated, in this paper, we examine the Na⁺ current flowing through the L- and R-type Ca²⁺ channels of labyrinth hair cells. Ion currents and cytosolic free Ca²⁺ concentrations were simultaneously monitored in whole-cell recording synchronous to fast fluorescence imaging. L-type and R-type channels were present with different densities at selected sites. In 10 nM Ca²⁺, the activation and deactivation time constants of the L-type Na⁺ current were accelerated and its maximal amplitude increased by 6-fold compared to physiological Ca²⁺. The deactivation of the R-type Na⁺ current was not accelerated, and its current amplitude increased by 2.3-fold in low Ca²⁺; moreover, it was partially blocked by nifedipine in a voltage- and time-dependent manner. In conclusion, L channel gating is affected by the ion species permeating the channel, and its selectivity filter binds Ca²⁺ more strongly than that of R channel; furthermore, external Ca²⁺ prevents nifedipine from perturbing the R selectivity filter.     

Aquaporins Are One of the Critical Factors in the Disruption of the Skin Barrier in Inflammatory Skin Diseases

The skin is the largest organ of the human body, serving as an effective mechanical barrier between the internal milieu and the external environment. The skin is widely considered the first-line defence of the body, with an essential function in rejecting pathogens and preventing mechanical, chemical, and physical damages. Keratinocytes are the predominant cells of the outer skin layer, the epidermis, which acts as a mechanical and water-permeability barrier. The epidermis is a permanently renewed tissue where undifferentiated keratinocytes located at the basal layer proliferate and migrate to the overlying layers. During this migration process, keratinocytes undertake a differentiation program known as keratinization process. Dysregulation of this differentiation process can result in a series of skin disorders. In this context, aquaporins (AQPs), a family of membrane channel proteins allowing the movement of water and small neutral solutes, are emerging as important players in skin physiology and skin diseases. Here, we review the role of AQPs in skin keratinization, hydration, keratinocytes proliferation, water retention, barrier repair, wound healing, and immune response activation. We also discuss the dysregulated involvement of AQPs in some common inflammatory dermatological diseases characterised by skin barrier disruption.