基于三维软件的机械产品设计

针对企业采用传统的2D软件设计产品过程中,存在着低效率、易出错等缺点,提出了采用三维SolidWorks软件来定制企业内部模板,进行实体建模,自动生成符合国标的工程图等产品的详细设计过程,并通过一些典型产品的设计实例进行了说明。     

移动位置服务中一种空间智能发布系统模型

与现有的位置服务模式相比,基于Push(推)模式的位置服务有着更加广阔的市场前景,是目前国内外研究的焦点.该模式的位置服务依赖于现存的空间发布系统,而目前空间发布系统由于条件的限制不能有效地完成空间事件的预订和发布.阐述了目前空间发布系统中两种常见的空间事件以及空间事件的预订,随后提出一种空间智能发布系统模型,有效地解决了无线通信的带宽限制问题并提高了空间发布系统的性能.     

硅通孔转接板封装结构多尺度问题的有限元模型

三维硅通孔转接板封装结构中,存在大量的微凸点与微焊球,尺寸相差3个数量级,这种结构多尺度给有限元分析模型的建立带来困难。以板级封装焊锡接点热疲劳寿命的有限元计算为目标,采用均匀化方法将芯片与转接板间的微凸点/下填料层以及转接板与基板间的微焊点/下填料层等效为均匀介质,以解决结构多尺度带来的网格划分困难。在对比分析了几种均匀化方案的基础上,建议在计算三维硅通孔转接板板级封装焊锡接点的热疲劳寿命时,芯片与转接板间的微凸点/下填料层以及转接板与基板间的微焊点/下填料层可采用各自的下填料层替代建模。     

力法非线性梁柱单元的合理单元长度划分

针对目前结构非线性分析中最常用的力法非线性梁柱单元模型,从理论上分析出了能消除其计算失真问题的合理单元长度及对应积分点数量。然后基于OpenSees有限元程序,使用该理论分析结果建立了一组单墩循环推倒试验的数值分析模型,通过加载点力-位移滞回曲线的对比分析和墩底截面曲率滞回曲线的对比分析验证了理论结果的正确性。结果表明：使用力法非线性梁柱单元模型进行结构的非线性数值分析时,其单元长度划分应根据积分点数量确定,确定原则应基于使单元屈服后变形增长的分布长度与塑性铰长度相等进行计算;在实际使用中,可利用等效塑性铰长度计算积分点数量与单元长度的关系,初步确定单元划分的合理长度;在保证单元长度与积分点数量的对应关系前提下,力法非线性单元的积分点数量越多,计算结果越稳定。     

Pharmacophore Synergism in Diverse Scaffold Clinches in Aurora Kinase B

Aurora kinase B (AKB) is a crucial signaling kinase with an important role in cell division. Therefore, inhibition of AKB is an attractive approach to the treatment of cancer. In the present work, extensive quantitative structure–activity relationships (QSAR) analysis has been performed using a set of 561 structurally diverse aurora kinase B inhibitors. The Organization for Economic Cooperation and Development (OECD) guidelines were used to develop a QSAR model that has high statistical performance (R²_tr = 0.815, Q²_LMO = 0.808, R²_ex = 0.814, CCC_ex = 0.899). The seven-variable-based newly developed QSAR model has an excellent balance of external predictive ability (Predictive QSAR) and mechanistic interpretation (Mechanistic QSAR). The QSAR analysis successfully identifies not only the visible pharmacophoric features but also the hidden features. The analysis indicates that the lipophilic and polar groups—especially the H-bond capable groups—must be present at a specific distance from each other. Moreover, the ring nitrogen and ring carbon atoms play important roles in determining the inhibitory activity for AKB. The analysis effectively captures reported as well as unreported pharmacophoric features. The results of the present analysis are also supported by the reported crystal structures of inhibitors bound to AKB.     

The Impact of the Azo-Chromophore Sort on the Features of the Supramolecular Azopolyimide Films Desired to Be Used as Substrates for Flexible Electronics

High-performance supramolecular polyimide systems were synthesized via a simple and innovative approach using two types of azo-chromophores, leading to concomitant special properties: high thermostability, the ability to be processed in the form of films with high flexibility, adequate morphological features, and good structuring capacity via phase mask ultraviolet (UV) laser irradiation, induced by the presence of the azo groups (–N=N–). The dimension and the anisotropy degree of the micro/nano patterns obtained on the surface of the flexible films (determined by atomic force microscopy) depend on the azo-dye type used in the supramolecular azopolyimide synthesis, which were higher when the azo-chromophore containing a –cyano group (–C≡N) was used. The molecular dynamics method, an excellent tool for an in-depth examination of the intermolecular interactions, was used to explain the morphological aspects. Energetic, dynamic and structural parameters were calculated for the two systems containing azo-chromophores, as well as for the pristine polymer system. It was highlighted that the van der Waals forces make a major contribution to the intermolecular interactions. The results from the combination of the dynamic analysis and the concentration profile explain the better mobility of the polyimide chains with a maximum content of azo groups in the cis configuration compared to the other systems. Taking all these data into account, the surfaces of the films can be tuned as required for the proposed applications, namely as substrates for flexible electronis.     

Performance Analysis of a HT-PEMFC System with 6FPBI Membranes Doped with Cross-Linkable Polymeric Ionic Liquid

In this paper, a high-temperature proton-exchange membrane fuel cell (HT-PEMFC) system using fluorine-containing polybenzimidazole (6FPBI) composite membranes doped with cross-linkable polymer ionic liquid (cPIL) is developed and studied. The reliability of the model is verified by a comparison with the experimental data. The performance of the HT-PEMFC system using 6FPBI membranes with different levels of cPIL is analyzed. The results show that when the HT-PEMFC uses 6FPBI membranes with a cPIL content of 20 wt % (6FPBI-cPIL 20 membranes), the single cell power density is 4952.3 W·m−2. The excessive cPIL content will lead to HT-PEMFC performance degradation. The HT-PEMFC system using the 6FPBI-cPIL 20 membranes shows a higher performance, even at higher temperatures and pressures, than the systems using 6FPBI membranes. In addition, the parametric study results suggest that the HT-PEMFC system should be operated at a higher inlet temperature and hydrogen pressure to increase system output power and efficiency. The oxygen inlet pressure should be reduced to decrease the power consumption of the ancillary equipment and improve system efficiency. The proposed model can provide a prediction for the performance of HT-PEMFC systems with the application of phosphoric-acid-doped polybenzimidazole (PA-PBI) membranes.     

Radiation hardened design and analysis of radiation effect for scientific CMOS image sensor

A systemic solution for radiation hardened design is presented. Besides, a series of experiments have been carried out on the samples, and then the photoelectric response characteristic and spectral characteristic before and after the experiments have been comprehensively analyzed. The performance of the CMOS image sensor with the radiation hardened design technique realized total-dose resilience up to 300 krad(Si) and resilience to single-event latch up for LET up to110 MeV·cm²/mg.     

承钢钒铁炉底吹N2水模型试验研究

通过建立1：2的比例的水力学模型,对承德钢铁集团有限公司钒铁车间2t的钒铁炉底吹N₂进行了水力学模拟实验,同时利用正交分析,主要考察了不同的吹气孔位置、吹气流量对铁水混匀时间以及熔池流态的影响.结果表明：不同的底吹气孔组合以及气体流量的控制,会对熔池的混匀产生很大的影响.对实验数据采取正交分析,可以发现当吹气孔位置为e-b-d,吹气流量为1092 L·min^-1时,气体对熔池的搅拌能力是最强的,此时铁水混匀所需时间最短,且流场分布合理.