开关电源高频变压器电容效应建模与分析

该文分析了开关电源中高频变压器在考虑了变压器绕组导体的电位分布情况下的电场储能特性和共模电磁干扰发射特性。指出采用一端口入端电容描述电场储能效应，而采用二端口转移阻抗电容描述共模电磁干扰发射效应，并提出了相应的参数计算方法。在此基础上，建立了新的高频变压器电容效应模型，该模型可以同时兼顾变压器的电场能量储存特性和共模噪音抑制特性，能合理地揭示变压器内共模噪音电流的流动机理。实验和仿真结果均验证了理论分析和模型。     

Research on a New Hybrid System of a Tyre Crane Using Supercapacitors

Research on a hybrid system of a crane is a focus which considers environmental protection and energy saving.A new environmental protection and energy saving hybrid system of tyre crane.which utilizes supercapacitors as the energy store device,is presented.Analyzing the pdneiple of supercapacitors,the model of the crane's hybrid system is set up in this paper,and the model of main blocks are established.Through simulation analyzing,the energy saving result of the new hybrid system is obtained,and the good application value of the new hybrid system is explained.     

基于命令流方法的液压机ANSYS有限元建模

介绍了命令流方法在液压机ANSYS有限元建模的起因和用途,并作了实例建模,最后指出对计算机应用软件的二次开发在液压机结构设计中的必要性.     

Thiogenistein—Antioxidant Chemistry,Antitumor Activity,and Structure Elucidation of New Oxidation Products

Isoflavonoids such as genistein (GE) are well known antioxidants. The predictive biological activity of structurally new compounds such as thiogenistein (TGE)–a new analogue of GE–becomes an interesting way to design new drug candidates with promising properties. Two oxidation strategies were used to characterize TGE oxidation products: the first in solution and the second on the 2D surface of the Au electrode as a self-assembling TGE monolayer. The structure elucidation of products generated by different oxidation strategies was performed. The electrospray ionization mass spectrometry (ESI-MS) was used for identifying the product of electrochemical and hydrogen peroxide oxidation in the solution. Fourier transform infrared spectroscopy (FT-IR) with the ATR mode was used to identify a product after hydrogen peroxide treatment of TGE on the 2D surface. The density functional theory was used to support the experimental results for the estimation of antioxidant activity of TGE as well as for the molecular modeling of oxidation products. The biological studies were performed simultaneously to assess the suitability of TGE for antioxidant and antitumor properties. It was found that TGE was characterized by a high cytotoxic activity toward human breast cancer cells. The research was also carried out on mice macrophages, disclosing that TGE neutralized the production of the LPS-induced reactive oxygen species (ROS) and exhibits ABTS (2,2′-azino-bis-3-(ethylbenzothiazoline-6-sulphonic acid) radical scavenging ability. In the presented study, we identified the main oxidation products of TGE generated under different environmental conditions. The electroactive centers of TGE were identified and its oxidation mechanisms were proposed. TGE redox properties can be related to its various pharmacological activities. Our new thiolated analogue of genistein neutralizes the LPS-induced ROS production better than GE. Additionally, TGE shows a high cytotoxic activity against human breast cancer cells. The viability of MCF-7 (estrogen-positive cells) drops two times after a 72-h incubation with 12.5 μM TGE (viability 53.86%) compared to genistein (viability 94.46%).     

An integrated modeling method for prediction of sulfur content in agglomerate

1　INTRODUCTIONSomeparametersincomplex process,especiallyinmetallurgicandchemicalprocess ,needtobepredictedforsecurityandefficiencyofproduction .PrecisepredictionofsulfurinagglomerateissignificantforsinteringprocessinPb ZnImperialSmeltingProcess (ISP) [1] .SinteringprocessistodesulfurateandsinterPb ZnminesoastoprovideagglomerateforPb Znproduction .Ifthesulfurcontentinagglomerateexceeds 1% ,thesmeltingprocesscannotrunfluentlyandtheconditionsaredeterioratedre markably .Inspiteoftheimpo…     

Proton exchange membrane fuel cells modeling based on artificial neural networks

To understand the complexity of the mathematical models of a proton exchange membrane fuel cell (PEMFC) and their shortage of practical PEMFC control, the PEMFC complex mechanism and the existing PEMFC models are analyzed, and artificial neural networks based PEMFC modeling is advanced. The structure, algorithm, training and simulation of PEMFC modeling based on improved BP networks are given out in detail. The computer simulation and conducted experiment verify that this model is fast and accurate, and can be used as a suitable operational model for PEMFC real-time control.     

内涝型流域洪灾洪水模拟

本文讨论内涝型流域的特点和流域模拟概化的方法，建立了内涝型流域洪灾洪水模拟数值模型软件，并以太湖流域为试验区进行了应用，结果表明了模型的可行性和有效性，且具有可扩充性、可移值性和通用性。     

基于SolidWorks的三螺杆泵螺杆参数化建模系统开发

三螺杆泵螺杆是具有特殊摆线齿形的轴类零件,它在各种三维设计软件中的造型比较复杂。根据三螺杆泵主从螺杆摆线齿形方程,利用SolidWorks API二次开发工具,用VBA语言编程,研究<135>型三螺杆泵主从螺杆参数化建模的方法,实现了三螺杆泵主从螺杆的参数化三维建模。     

Base‐Pairing Behavior of a Carbocyclic Janus‐AT Nucleoside Analogue Capable of Recognizing A and T within a DNA Duplex

Janus‐type nucleosides are heterocycles with two faces, each of which is designed to complement the H‐bonding interactions of natural nucleosides comprising a canonical Watson–Crick base pair. By intercepting all of the hydrogen bonds contained within the base pair, oligomeric Janus nucleosides are expected to achieve sequence‐specific DNA recognition through the formation of J‐loops that will be more stable than D‐loops, which simply replaces one base‐pair with another. Herein, we report the synthesis of a novel Janus‐AT nucleoside analogue, J_AT, affixed on a carbocyclic analogue of deoxyribose that was converted to the corresponding phosphoramidite. A single J_AT was successfully incorporated into a DNA strand by solid phase for targeting both A and T bases, and characterized through biophysical and computational methods. Experimental UV‐melting and circular dichroism data demonstrated that within the context of a standard duplex, J_AT associates preferentially with T over A, and much more poorly with C and G. Density functional theory calculations confirm that the J_AT structure is well suited to associate only with A and T thereby highlighting the importance of the electronic structure in terms of H‐bonding. Finally, molecular dynamics simulations validated the observation that J_AT can substitute more effectively as an A‐analogue than as a T‐analogue without substantial distortion of the B‐helix. Overall, this new Janus nucleotide is a promising tool for the targeting of A–T base pairs in DNA, and will lead to the development of oligo‐Janus‐nucleotide strands for sequence‐specific DNA recognition.     

The effect of the shape and size of the pores on the mechanical properties of porous HAP-based bioceramics

In this study, the influence of the shape and size of the pores on the mechanical properties of the obtained porous HAP-based bioceramics was investigated. The porous HAP-based bioceramics were obtained starting from spherical calcium hydroxyapatite powder, obtained by hydrothermal syntheses. The number of shapeless inter-agglomerate pores decreased and amount of spherical intra-agglomerate pores increased on increasing the sintering temperature from 1100 °C to 1250 °C. The shape of pores also changed with thermal treatment of specimens; the small pores remained spherical while the larger pores became more spherical in shape, as was proved by image analysis. A three-dimensional, finite element unit cell model was applied to evaluate the influence of pore shape on the mechanical strength of HAP ceramics. By analyzing the effect of the shape of pores to the fracture toughness of sintered porous HAP bioceramics, it was observed that the more spherical the pores were, the tougher became the bioceramics. After sintering at 1250 °C for 2 h, measured toughness was 1.31 MPa m^1/2, which is a relatively high value for this type of bioceramics.