综合体内儿童活动场所执行消防规范的问题探讨

近年来,我国城市商业综合体的总数和规模出现了前所未有的增长,各种儿童活动场所在商业综合体内遍地开花,不少商业综合体甚至主打儿童品牌,成为满足儿童游乐、教育、摄影、零售、美食等多种需求的一站式基地。但此类场所的快速发展也带来了极大的火灾风险,相对消防法规和技术标准也出现了一些不适应、难执行的情况。文章对在商业综合体内设置的儿童活动场所执行现行消防法规和技术标准存在的问题及相应的解决措施进行分析,希望可以起到借鉴作用。     

Tumor-Localized Administration of α-GalCer to Recruit Invariant Natural Killer T Cells and Enhance Their Antitumor Activity against Solid Tumors

Invariant natural killer T (iNKT) cells have the capacity to mount potent anti-tumor reactivity and have therefore become a focus in the development of cell-based immunotherapy. iNKT cells attack tumor cells using multiple mechanisms with a high efficacy; however, their clinical application has been limited because of their low numbers in cancer patients and difficulties in infiltrating solid tumors. In this study, we aimed to overcome these critical limitations by using α-GalCer, a synthetic glycolipid ligand specifically activating iNKT cells, to recruit iNKT to solid tumors. By adoptively transferring human iNKT cells into tumor-bearing humanized NSG mice and administering a single dose of tumor-localized α-GalCer, we demonstrated the rapid recruitment of human iNKT cells into solid tumors in as little as one day and a significantly enhanced tumor killing ability. Using firefly luciferase-labeled iNKT cells, we monitored the tissue biodistribution and pharmacokinetics/pharmacodynamics (PK/PD) of human iNKT cells in tumor-bearing NSG mice. Collectively, these preclinical studies demonstrate the promise of an αGC-driven iNKT cell-based immunotherapy to target solid tumors with higher efficacy and precision.     

双面印制板设计中如何控制电磁干扰

从零件放置、布线和补铜箔等三个方面讨论了在双面印制板设计中如何控制电磁干扰。实践证明 ,该方法控制电磁干扰比较有效且非常经济。     

舞台灯具国家标准特殊要求及LED舞台灯具的适用性

介绍了国家标准GB 7000.217-2008/IEC 60598-2-17：1984＋A2：1990《灯具第2-17部分：特殊要求舞台灯光、电视、电影及摄影场所（室内外）用灯具》的特殊要求,阐述了对该标准特殊要求条文的理解和解释以及其对LED舞台灯具的适用性,以帮助舞台灯具行业的设计、生产、检验和使用人员正确理解和应用舞台灯具国家标准。     

浅谈人-机-环境理论在电力安全中的应用

通过人、机、环境安全理论对电力系统内部的不安全因素进行分析,以期从根本上找出事故发生的原因,从而找出解决问题的途径。     

谐振式强磁耦合无线能量传输及其在民用电安全方面的应用

介绍当前几种主流的无线能量传输技术方案,并比较了其优缺点.针对“谐振式强磁耦合无线能量传输”技术作一些深入的介绍,并展望其在民用电安全方面的一些应用.     

低压供电系统快速漏电保护技术

介绍了一种保证低压供电系统人身触电安全的漏电保护技术，并阐述了其基本原理，介绍了实现方案及实际应用情况。     

广电网络业务发展的分析

以促进广电网络发展为纲,分析广电主要的3项增值业务:付费频道,高清互动,宽带业务。从实际出发,分析现状并为其正确定位,对其发展方向及业务增长方式题出建议,指出广电未来以电视业务宽带业务为主线的盈利格局。     

电力互感器现场试验安全分析

针对目前电流互感器和电压互感器的现场误差测试工作,简要分析了所存在的安全薄弱点及产生的原因,指出这些危险点大都是由一些习惯违章和思想松懈所致。最后提出了一些改进和防范措施。     

Current Opinion in LAIV: A Matter of Parent Virus Choice

Influenza is still a frequent seasonal infection of the upper respiratory tract, which may have deadly consequences, especially for the elderly. This is in spite of the availability of vaccines suggested for persons above 65 years of age. Two types of conventional influenza vaccines are currently licensed for use—live attenuated and inactivated vaccines. Depending on local regulatory requirements, live attenuated vaccines are produced by the reverse genetics technique or by classical reassortment in embryonated chicken eggs. Sometimes, the efficiency of classical reassortment is complicated by certain properties of the wild-type parent virus. Cases of low efficacy of vaccines have been noted, which, among other reasons, may be associated with suboptimal properties of the wild-type parent virus that are not considered when recommendations for influenza vaccine composition are made. Unfortunately, knowledge surrounding the roles of properties of the circulating influenza virus and its impact on the efficacy of the reassortment process, vaccination efficiency, the infectivity of the vaccine candidates, etc., is now scattered in different publications. This review summarizes the main features of the influenza virus that may dramatically affect different aspects of the preparation of egg-derived live attenuated vaccine candidates and their effectiveness. The author expresses her personal view, which may not coincide with the opinion of other experts in the field of influenza vaccines.