基于QFD与FBS模型的坐便器多适性设计研究

目的 设计能够适应多类用户群体的多适性坐便器,让老年用户也能够平等的使用。方法 以针对一般群体的主流坐便器为设计基础,合理融入老年人群的特殊需求。运用质量功能展开（Quality Function Deployment,QFD）建立多适性坐便器用户需求与设计要求关系矩阵,确定关键设计要求的目标作为功能引入FBS（Function-Behavior-Structure）模型,最终获得坐便器结构化信息。结论 结合运用QFD和FBS模型展开的坐便器多适性设计研究,能够精确有效地将用户需求转化为设计要求,使最终的产品客观表现与用户需求之间能够精准映射匹配。同时验证了QFD和FBS融合应用的可行性和有效性。     

一种移动背景下的污染气体遥感探测算法

作为一种有效的大气污染气体遥感探测识别手段,傅里叶变换红外光谱仪已经得到越来越广泛的应用。当污染气体与背景存在温差时,红外光谱就能反映出污染气体的吸收或发射特征。利用布鲁克公司的OPAG 22型光谱仪采样得到2048点的干涉图,当采用合适的信号处理算法时,可以在不需要预先测量背景的前提下直接分析干涉图得到污染气体的特征信号。本文介绍的快速背景扣除算法在污染气体的特征峰是单峰、多峰等情况下都能快速有效地扣除掉低频背景信号,检出目标特征。这一方法为快速移动背景下的污染气体探测识别研究提供了一个快速简便的方法。     

The correlation between skin-care effects and phytochemical contents in Lamiaceae plants

In this study, well-known skin-care functional parameters were used, including UV absorption, DPPH-scavenging, NO-production-inhibition, tyrosinase-inhibition activity and anti-Staphylococcus aureus activity to measure the effects of the 70% acetone-extracts form 28 species of Lamiaceae plants. Further, the phytochemical contents were explored by total phenol (TP), total flavone (TF) and total coumarin (TC). The correlation between the skin-care effects and the phytochemical contents was analysed by non-parametric correlation analysis. Amongst the 70% acetone-extracts, Origanum majorana displayed the strongest DPPH-scavenging and tyrosinase-inhibitory effects and the richest phenol content. Based on the statistics results, the phytochemical contents were related with those parameters, such as: DPPH-scavenging effects vs. TP (R = 0.542), TF vs. TP (R = 0.613), and NO-inhibitory vs. anti-bacterial activities (R = 0.767). Moreover, each genus of Lamiaceae had different properties of skin-care effects. Form our research works, the Lamiaceae is good resources to develop skin-care cosmetics.     

Limited contribution of isoflavones to hepatocellular phase II enzyme-inducing activity of soybean (Glycine max) extracts

Soy flour was successively extracted with ethyl acetate, ethanol, and water and tested for quinone reductase (QR) induction in the Hepa 1c1c7 cell line. The ethanol extract was found to be the most potent, with a CD value (concentration required to double QR specific activity) of 460 μg/ml. Phase separation of the ethanol extract and a phospholipid removal procedure yielded a fraction that doubled QR at 80 μg/ml. Reverse phase medium pressure chromatography of the purified ethanol extract yielded 13 fractions. Constituents of selected fractions were identified using mass spectrometry and NMR analysis. Fractions 2, 8, and 10 contained 47% of the recovered mass and were the least active of the isolates. These three fractions contained isoflavone glycosides. The latest eluting fractions 11–13 were found to be the most potent, and contained the majority of recovered inducing units (IUs), a measure of potency.     

基于功能本体的面向目的创新设计研究

为了使新产品的创新设计过程可以有效的进行,在功能表达和功能建模过程中引入本体概念.融合人的认知过程,建立了基于功能本体、功能行为结构(FBS)和XML数据存储表达方式的面向目的创新设计过程.开发了面向目的创新的原型系统模块,最后讨论所建立的系统,给出系统应用例子说明系统的有效性.     

Immunomodulatory effects of feruloylated oligosaccharides from rice bran

Feruloylated oligosaccharides (FOs), the ferulic acid ester of oligosaccharides, can be released either by the enzymatic or mild acid hydrolysis of arabinoxylans present in cereal bran, and are usually considered as natural antioxidants. However, no related research is available to explain their immunomodulatory effects. This report elucidated their immunomodulatory effects through the variations of pro-inflammatory mediators in vitro. FOs were obtained from the mild acid hydrolysis of rice bran. We found that FOs (0.1–100 μg/ml) induced tumour necrosis factor alpha (TNF-α), IL-1β, IL-6, nitric oxide (NO) and PGE₂ production in unstimulated macrophages, RAW264.7 cells. Furthermore, pre- and post-treated FOs (0.1–100 μg/ml) dose-dependently suppressed TNF-α, IL-1β, IL-6 and NO production, and induced IL-10 production in lipopolysaccharide (LPS)-stimulated RAW264.7 cells without exerting cytotoxicity. As a result anti-inflammatory and therapeutic activities were revealed. It is noteworthy that prostaglandin E₂ (PGE₂) production was significantly suppressed at an FO level of 100 μg/ml. The in vitro assessment of inflammatory mediators should be useful in further characterising the effects of FOs on immunomodulation. Moreover, it will create the economical value of rice bran, which has long been considered as conventional agricultural wastes.     

基于FBS和AHP的AI大模型辅助无障碍智能轮椅设计研究

目的 旨在探索Co-Design视域下,针对行动障碍者,设计一款无障碍智能轮椅产品。方法 该研究整体上利用FBS设计模型的宏观思维,确立了以用户的行为和功能需求映射产品结构的研究思路,并利用AHP层次分析理论寻找用户需求和产品功能要素的最优解,进而发现针对特定群体的无障碍轮椅设计痛点,最后通过将设计痛点输入AI大模型,进行迭代设计和方案优化,直至产生最优的设计方案。结论 根据对用户群体需求指标的AHP层次分析,用户对轮椅安全性和舒适性的需求最为强烈,这从根本上确定了用户潜在的行为特征,以及用户对无障碍轮椅设计的功能需求,进而从整体上确定了该无障碍轮椅的产品结构与功能。     

基于CMR+FBS方法模型的家庭智能体交互设计

目的 FBS（即功能—行为—结构）认知计算设计模型对内容容器的设计缺乏对应的有效指导方法。本文提出针对内容功能关系需求的CMR认知计算设计模型,探讨家庭智能体交互设计的功能与内容设计的本体论框架。方法 除了在家庭智能体的功能设计中引入FBS模型,本文还提出了针对智能体及人机交互内容设计的CMR（即内容—心智及交互模型—需求与关系）设计模型。其中,内容包括用户自身产生内容（UGC）、专业生产内容（PGC）、职业生产内容（OGC）,以及本文提出的生态系统生成内容（EGC）。本文提出CMR+FBS方法模型,分析了功能任务与内容描述之间的转换关系,并将CMR+FBS模型应用于百度智能音箱项目的研究中,对其唤醒功能的设计进行了分析。结论 FBS模型与CMR模型的结合能够支持高度灵活的智能体产品设计和数据服务的交互设计,CMR模型是提供高满意度用户体验的关键因素。寻求功能任务需求与构建用户生成内容的人机交互（HRI）关系是智能产品交互设计的新方法。