全封闭大功率永磁牵引电机的温度场数值计算

为研究全封闭大功率永磁牵引电机额定工况下的稳态温度场,以一台额定功率为815 kW的永磁同步牵引电机为研究对象,依据成型绕组槽部导热模型,建立了整机三维温度场共轭传热计算模型。考虑旋转磁化、冲压过程和磁密高阶谐波对定子铁耗的影响,以及水套-定子铁心间接触热阻抗对电机温升的影响,采用Fluent软件对电机额定工况下的稳态流场与温度场求解,使用电阻法和埋置检温计法（ETD）测得电机在额定工况下绕组的平均温升、铁心测点和绕组端部测点局部温升,绝对误差分别为-3.7 K、-0.3 K和7.6 K。进一步分析了电机水路和内风路流场分布特性、水套-定子铁心间接触间隙对绕组平均温升的影响以及槽内绕组附近的温升分布情况,最后提出了该类电机冷却系统设计优化方向。     

A Novel Artificially Humanized Anti-Cripto-1 Antibody Suppressing Cancer Cell Growth

Cripto-1 is a member of the EGF-CFC/FRL1/Cryptic family and is involved in embryonic development and carcinogenesis. We designed a novel anti-Cripto-1 artificial antibody and assessed the recognition to the antigen and the potential to suppress the growth of cancer stem cells. First, single chain antibody clones were isolated by bio-panning with the affinity to recombinant Cripto-1 protein from our original phage-display library. Then, the variable regions of heavy chain VH and light chain VL in each clone were fused to constant regions of heavy chain CH and light chain CL regions respectively. These fused genes were expressed in ExpiCHO-S cells to produce artificial humanized antibodies against Cripto-1. After evaluation of the expression levels, one clone was selected and the anti-Cripto-1 antibody was produced and purified. The purified antibody showed affinity to recombinant Cripto-1 at 1.1 pmol and immunoreactivity to cancer tissues and cell lines. The antibody was available to detect the immunoreactivity in tissue microarrays of malignant tumors as well as in Cripto-1 overexpressing cells. Simultaneously, the antibody exhibited the potential to suppress the growth of human colon cancer derived GEO cells overexpressing Cripto-1 with IC₅₀ at approximately 110 nM. The artificially humanized antibody is proposed to be a good candidate to target cancer cells overexpressing Cripto-1.     

改进的永磁同步电机双矢量模型预测转矩控制

针对永磁同步电机（PMSM）传统模型预测转矩控制（MPTC）权重系数设置复杂、转矩和磁通脉动大的问题,提出了一种改进的PMSM双矢量MPTC方法。该方法扩展虚拟矢量以增加候选电压矢量,结合电压矢量作用于转矩和磁链的原则,减少选择候选矢量的计算量。同时,针对转矩无差拍和磁通无差拍,运用候选矢量的转矩占空比和磁通占空比构造了优化规则代替传统预测转矩控制中的代价函数,避免权重系数的整定问题。仿真结果表明,所提改进方法不仅提高稳态性能,而且能保持MPTC动态响应迅速的特点。     

基于模型预测的PMSM速度环PI自整定控制

与传统的矢量控制相比,有限集模型预测控制（FCS-MPC）通过算法直接得到驱动信号,省略了脉宽调制环节,且响应性能也比较优越。利用改进型FCS-MPC算法,构建只含有转速环的控制系统传递函数,针对负载变化和参数扰动的工况,分别利用传递函数的频率特性分析法和典型系统整定法设计基于速度环的PI自整定方案。经过仿真对比验证,发现在该控制方法下因负载转矩和参数变化引起转速变化的波动更小且恢复时间更短,证明了该方法的可行性和有效性。     

基于Super-Twisting算法的内燃机车永磁同步发电系统策略研究

为了使内燃机车永磁同步发电系统在内燃机全速范围内和突变性负载条件下均能稳定控制中间直流环节电压且减小电压的脉振,采用Super-Twisting高阶滑模算法对电压外环进行控制得到给定转矩,与传统PI外环控制相比,中间直流环节电压开始的超调减小,且电压跟随性、稳定性得到提升。同时,为了提高发电系统变流器容量利用率,在矢量控制的基础上,提出改进的功率因数控制策略对电机进行控制。仿真试验表明,所提发电系统在内燃机宽转速范围、突变性负载条件下,可以得到平稳且能够快速恢复的中间直流电压。同时,发电系统在切换转矩内无功功率基本能稳定在零附近,超过切换转矩后无功功率依旧保持较低水平,提高了变流器容量利用率。     

基于改进快速幂次趋近律的永磁同步电机滑模控制

针对永磁同步电机(PMSM)滑模控制指数趋近律中趋近速度与抖振之间的矛盾问题,基于快速幂次趋近律提出一种幂次项系数自适应调节的新型趋近律。所提趋近律将系统状态引入幂次项系数中,实现了系统状态由较远处到滑模面附近的趋近过程中加入幂次项的作用,在保证幂次项特点的前提下,动态响应过程的收敛速度大大提高。负载转矩是滑模速度控制器中的一个扰动项,设计了带有幂次项的滑模观测器,将观测值作为转矩前馈补偿。仿真结果表明,与快速幂次趋近律相比,所提趋近律具有更快的收敛速度,负载观测器能准确跟踪负载变化,提升了系统抗扰性能。     

Improvement of coercivity and thermal stability of Nd-Fe-B sintered magnets by intergranular addition of Tb80Fe20 alloy

To improve the coercivity and temperature stability of Nd-Fe-B sintered magnets for high-temperature applications, the eutectic Tb₈₀Fe₂₀ (wt%) alloy powders were added into the Nd-Fe-B sintered magnets by intergranular method to enhance the coercivity (H_cj) and thermal stability. The microstructure, magnetic properties and thermal stability of the Nd-Fe-B magnets with different Tb₈₀Fe₂₀ contents were studied. The experimental results demonstrate that the coercivity (H_cj) of the sintered Nd-Fe-B magnet is significantly enhanced from 14.12 to 27.78 kOe, and the remanence (B_r) decreases not obviously by introducing 4 wt% Tb₈₀Fe₂₀ alloy. Meanwhile, the reversible temperature coefficients of coercivity (β) and remanence (α) of the Nd-Fe-B magnets are increased from ?0.5634%/℃ to ?0.4506%/℃ and ?0.1276%/℃ to ?0.1199%/℃ at 20–170 ℃, respectively. The Curie temperature (T_C) of the Nd-Fe-B magnet is slightly enhanced with the increase of Tb₈₀Fe₂₀ content. Moreover, the irreversible flux magnetic loss (h_irr) is obviously reduced as Tb₈₀Fe₂₀ addition increases. Further analysis of the microstructure reveals that a modified microstructure, i.e. clear and continuous RE-rich grain boundary layer, is acquired in the sintered magnets by introducing Tb₈₀Fe₂₀ alloy. The associated mechanisms on improved coercivity and thermal stability were comprehensively researched.     

Mo的替代对FeNbBCu软磁纳米晶合金磁谱的影响

本文研究了Fe82Nb7-xMoxB10Cu1(x=0,1,3,5）系列纲伙晶软磁合金中Mo的含量对磁导率谱（频率范围1kHz-1MHz)的影响，并用畴壁钉扎理论进行了解释，在磁谱中观测到随着Mo含量的增加，弛豫频率线性地上升，μ′随外加磁场幅度变化曲线表明其原因在于Mo的替代导致了钉扎场的增强。