6106型柴油机排气阀失效分析

6106型柴油机在载重车上运行4万公里和8万公里后发生排气阀"掉头"和"掉块"事故,本文对失效排气阀的金相组织和断口进行了观察分析,分析结果表明,金相组织正常,可以排除冶金质量和热处理的问题,发生在颈部的"掉头"事故,是由于机加工精度不高,表面存在"沟槽"引起.发生在盘部的"掉块"事故,是由于21-4N钢高温强度不足引起的.     

叠加阀在组合机床液压系统中的应用

文章简要介绍了新型液压元件--叠加阀,并列举实例说明了在组合机床中采用叠加阀的液压系统设计.     

Using anatomical knowledge expressed as fuzzy constraints to segment the heart in CT images

Segmenting the heart in medical images is a challenging and important task for many applications. In particular, segmenting the heart in CT images is very useful for cardiology and oncological applications such as radiotherapy. Although the majority of methods in the literature are designed for ventricle segmentation, there is a real interest in segmenting the heart as a whole in this modality. In this paper, we address this problem and propose an automatic and robust method, based on anatomical knowledge about the heart, in particular its position with respect to the lungs. This knowledge is represented in a fuzzy formalism and it is used both to define a region of interest and to drive the evolution of a deformable model in order to segment the heart inside this region. The proposed method has been applied on non-contrast CT images and the obtained results have been compared to manual segmentations of the heart, showing the good accuracy and high robustness of our approach.     

A NEW BATO COMPLEX^99mTcCl（4—MCDO）3MeB FOR MYOCARDIAL IMAGING

A new nertral complex,^99mTcCl(4-MCDO)3MEB,((Bis[4-methyl-1,2-cyclohex-anedionedioximato(1-)-O]-[4-methyl-1,2-cyclohexanedione-dioximato(2-)-O] methyl-borato(2-)-N,N‘,N″,N‘‘‘,N‘‘‘‘0-chlorotechnetium,generally called BATO(Boronic acid adducts of technitium dioximes),has been synthesized and evaluated for potential use in myocardial perfusion imaging,It has intrinsic affinity for the blood clearance.The uptake of heart.lung and blood in mice at 2min separately are 1.12,2.48 and 6.66%ID.The complex formation is rapid,simple and highly yielded(≥93%).This process is easy to kit formation.     

All‐Organic Dual Spin Valves with Well‐Resolved Four Resistive‐States

The formation of all‐organic dual spin valves (DSVs) with three organic spin‐selective layers, that is, spin‐injection, spin‐detection, and an additional spin‐filtering layer at the intermediate, is reported. As spin‐selective layers, manganese‐ and cobalt phthalocyanines, which are well‐known single‐molecule magnets, are used in their immobilized forms, so that all‐organic DSVs can be prefabricated for characterization. The three spin‐selective layers have provided four configurations with at most two spin‐flip interfaces enforcing spin‐flipping at the two nonmagnetic organic spacer layers, for which copper phthalocyanine is used. Since a couple of the four configurations have exhibited similar resistivities, the degeneracy in the resistive‐states is broken through asymmetric spin‐injection and spin‐detection layers and also through asymmetric thickness of the nonmagnetic spacer layers. When both the spin‐flip interfaces are made operative independently, a 2‐bit logic with four distinct resistive states can be achieved.     

Multi‐response optimization and empirical modeling of cardiopulmonary responses during manual lifting tasks

An experimental study involving five independent lifting variables (namely weight, lift frequency, horizontal distance from the object, operator, and vertical distance) and their interactions was conducted using the Taguchi L₂₇ design. Two responses—heart rate and oxygen uptake—were measured during each trial. To optimize both responses simultaneously, the signal‐to‐noise ratio was normalized to obtain a multi‐response signal‐to‐noise (MRSN) ratio for each trial. The MRSN ratio was analyzed using analysis of variance to identify the optimal condition in which both responses were optimized at the same time. Lift frequency was found to be the most significant factor, and operator and horizontal distance were found to be least significant. The empirical modeling equation was developed and can be used to predict the response values during experimental trials involving similar work conditions. © 2010 Wiley Periodicals, Inc.     

Quantification of heart fatty acid binding protein as a biomarker for drug-induced cardiac and musculoskeletal necroses

Heart fatty acid binding protein (Fabp3) is a cytosolic protein expressed primarily in heart, and to a lesser extent in skeletal muscle, brain, and kidney. During myocardial injury, the Fabp3 level in serum is elevated rapidly, making it an ideal early marker for myocardial infarction. In this study, an MS‐based selected reaction monitoring method (LC‐SRM) was developed for quantifying Fabp3 in rat serum. Fabp3 was enriched first through an immobilized antibody, and the protein was digested on beads directly. A marker peptide of Fabp3 was quantified using LC‐SRM with a stable isotope‐labeled peptide standard. For six quality control samples with Fabp3 ranging from 0.256 to 25 ng, the average recovery following the procedure was about 73%, and the precision (%CV) between replicates was less than 7%. The Fabp3 concentrations in rat serum peaked 1 h after isoproterenol treatment, and returned to baseline levels 24 h after the dose. Elevated Fabp3 levels were also detected in rats administered with a PPAR α/δ agonist, which has shown to cause skeletal muscle necrosis. Fabp3 can be used as a biomarker for both cardiac and skeletal necroses. The cross‐validation of the LC‐SRM method with an existing ELISA method is described.     

Factors affecting ambulatory heart rate in industrial workers†

The influence of several factors on the heart-rate (HR) response to tasks performed during regular work has been evaluated in a study population of 1654 male factory employees in Israel. Each worker was monitored for approximately one hour with an ambulatory electrocardiogram. The percentage change from resting HR decreased with increasing age and, as expected, was lower in sedentary workers than in manual workers. A highly significant negative correlation between the HR response and both systolic and diastolic blood pressure was found in the manual workers only. In further multiple regression analysis, after controlling for age, relative weight, smoking status, resting HR and the presence of abnormalities on the resting ECG, the association persisted for systolic BP only. Among young workers, both smoking and relative body weight were significantly associated with a higher HR response to work. Those with ECG abnormalities had lower HR response than those with normal ECGs, but not significantly so. These findings indicate that for roughly equivalent tasks and levels of resting HR, the HR response to regular work is influenced by several constitutional and behavioural factors. It may therefore be important to consider these factors when assigning workers to tasks involving strenuous effort.     

Metabolic and cardiovascular responses to exercise with caffeine

The effect of caffeine on circulation and metabolism was studied during a discontinuous maximal oxygen uptake (VO₂ max) test on a bicycle ergometer. Eight male subjects were chosen for their minimal use of caffeine of which six normally did not ingest caffeinated beverages. Two caffeinated and two decaffeinated (control) trials were administered to each subject following double-blind and counterbalanced testing procedures. One hour before exercise, subjects ingested decaffeinated coffee with or without 350 mg of caffeine anhydrous added. Cardiac output (Q) was measured by a C0₂ rebreathing technique. Compared to control trials, caffeine increased the VO₂ max by an average of 140ml min?¹ (p <0-0·5)l. In addition, during caffeine trials, the average maximal heart rate (HR max) was elevated by 5 beats min^?1 (p<0·01). There were no other statistically significant changes in metabolic (VO₂ and R) and cardiovascular (Q, HR, SV and (a-v) 0₂ diff) variables during either submaximal or maximal exercise. Performance, as measured by total exercise time on the VO₂ max test, was not significantly different (p>0·05). It was concluded that caffeine has a small physiological but a statistically significant effect on VQ₂ max and HR max. During submaximal exercise, caffeine did not significantly effect the cardiovascular system.