新型耐腐耐磨控制阀的研制

论述了陶瓷内件控制阀的研制，该阀内件同时具有耐腐蚀、耐磨损(包括冲刷、气蚀)与耐高温的性能。已获得成功应用。     

Towards a re-programmable DNA computer

Microreactors lend themselves to a relatively simple implementation of DNA computing. Not only is the design of the DNA library critical for the success of the system but also the architecture of the microfluidic structure. Microreactors can be configured as Boolean operators. This paper will show that biomolecular computing can be performed with elementary building blocks, analogous to electronic logic gates. These logical operations will be performed using negative selection. Furthermore, an alternative bead barrier is introduced which can render the computer re-programmable and shows an principle architecture for selection and analysis.     

壳牌粉煤气化装置用阀结构类型与特性的分析

介绍了壳牌粉煤气化装置中进口特种阀的选型和应用。论述了特种阀国产化需注意的问题。     

转炉干法除尘用杯形阀的研制

论述了转炉炼钢干法除尘系统切换站杯形阀的设计、作用、动作原理及结构特点。分析了杯形阀液压蓄能控制系统、开关控制系统和微调控制系统对阀门实施的启闭调节和控制。给出了放散阀和回收阀在正常或快速切换过程中所需油缸推力的选择和计算。     

Exposure to environmental carbon monoxide may have a greater negative effect on cardiac autonomic function in people with metabolic syndrome

Carbon monoxide (CO) has been recognized as a risk factor for adverse cardiovascular outcomes. We investigated the effects of CO on cardiac autonomic function by measuring the heart rate variability (HRV) in patients with and without metabolic syndrome (MetS). We also explored the relationship between CO exposure and specific components of MetS. Data were obtained from air pollution measurements and from health examinations on a total of 986 subjects, from a Korean community. Measurements of the 5-min HRV and examinations for MetS were conducted, and a linear regression model with a time lag was evaluated for any association. The group with MetS showed a significant reduction in the standard deviation of the normal-to-normal intervals (SDNN) and in the high frequency domain of HRV. After adjusting for age, sex, smoking status, day of the week effect, month effect, temperature, and relative humidity, these declines were significantly associated with exposure to CO for 25 to 48 h prior to the HRV measurement. Evidence for effect-modification by two specific MetS components, fasting blood glucose and triglycerides, was also observed in relation to CO exposure. These results suggest that CO exposure may trigger changes in cardiac autonomic function, and that subjects at high risk for heart disease may be more susceptible to CO effects.     

Validation of real-time PCR for detection of six major pathogens in seafood products

Seafood can pose a public health concern to consumers. It is often consumed raw and may be contaminated with several foodborne pathogens. In order to guarantee the safety of seafood, real-time polymerase chain reaction (PCR) protocols may be used as these enable results to be provided within 24 h.The first goal of our work was to develop real-time PCR protocols enabling the detection of six foodborne pathogens that may be present in seafood products (Campylobacter jejuni, Campylobacter coli, enterohemorrhagic Escherichia coli, Salmonella spp., Vibrio parahaemolyticus, and Vibrio vulnificus). The corresponding gene targets were: 50S/VS1, rfbE, ttr, tlh, and vvp. A multiplex PCR was also developed to detect the virulence genes of V. parahaemolyticus: tdh and trh. A total of 420 bacterial strains belonging to four different genera/strains were used in this study. Sensitivity and specificity were always 100%, except in the case of Salmonella spp., where three strains were not detected by our PCR protocols.The second objective of our work was to assess the detection limit of our real-time PCR protocols on artificially contaminated seafood products (raw shrimps, cooked shrimps, and raw mussels), purchased in public stores. Six different levels of contamination were assayed in four replicates for each matrix. The real-time PCR protocols enabled a better level of detection than the ISO methods, except for Salmonella in raw shrimps and for V. vulnificus in shrimps (raw and cooked). The estimated level of detection was between 1 and 47 cfu/25 g sample for the ISO norms and between 1 and 315 cfu/25 g sample for the real-time PCR protocols tailored in our work.The real-time PCRs developed in our work allowed for good selectivity, sensitivity, and specificity. The sensitivity on seafood products was estimated at a level of 100%, except for Salmonella (97%). In the spiking assays, the levels of detection were lower with the real-time PCR protocol than those obtained with the ISO method. This was not the case for V. vulnificus in raw and cooked shrimps and for Salmonella in raw shrimps.These real-time PCR protocols appear to be good alternative methods for surveillance of seafood products to ensure the absence of foodborne pathogens.One additional conclusion is that laboratories have to use enrichment media that are compatible with those recommended by ISO standards. This may facilitate the isolation of the pathogen if the real-time PCR protocol gives a suspect positive signal during the first step of the seafood analysis.     

600MW超临界直接空冷机组空冷系统防冻技术改造

针对极寒地区超临界直接空冷机组冬季易冻结问题,国华呼伦贝尔电厂在机组建设阶段进行了主汽疏水及在第2、6逆流段增设真空系统温度测点及在蒸汽蝶阀后增设温度测点的技术改造.改造后经过-47℃环境温度下运行与-30℃环境温度下启、停检验,未发生冻结现象,防冻效果良好,为极寒地区超临界直接空冷机组防冻提供了借鉴.     

Benefits of multiple micronutrient supplementation in heart failure: A comprehensive review

Abstract

Background: Multiple micronutrient supplementation has been suggested to have a role on health outcomes in patients with heart failure (HF), but the evidence is inconclusive. Objective: To elucidate the role of multiple micronutrient supplementation in heart failure we performed a comprehensive review of the literature. Methods and results: The search in databases included PUBMED (until June 2018) to detect randomized controlled trials (RCTs) and meta-analyzes that investigated the impact of micronutrient supplementation in HF. Results: With more than 2357 titles and abstracts reviewed, we included only the studies suitable for the final review. Whether alone or in combination, micronutrients have been found to improve the health outcomes of patients with HF by improving symptoms, work capacity and left ventricular ejection fraction (LVEF), thus increasing the quality of life in these patients. Conclusion: Future studies are needed to document the effects of multiple micronutrient associations in order to include them in nutritional guidelines to increase survival and to improve quality of life in patients with heart failure.     

Evaluation of physiological workload assessment methods using heart rate and accelerometry for a smart wearable system

Work metabolism (WM) can be accurately estimated by oxygen consumption (VO₂), which is commonly assessed by heart rate (HR) in field studies. However, the VO₂–HR relationship is influenced by individual capacity and activity characteristics. The purpose of this study was to evaluate three models for estimating WM compared with indirect calorimetry, during simulated work activities. The techniques were: the HR-Flex model; HR branched model, combining HR with hip-worn accelerometers (ACC); and HR?+?arm-leg ACC model, combining HR with wrist- and thigh-worn ACC. Twelve participants performed five simulated work activities and three submaximal tests. The HR?+?arm-leg ACC model had the overall best performance with limits of agreement (LoA) of ?3.94 and 2.00?mL/min/kg, while the HR-Flex model had ?5.01 and 5.36?mL/min/kg and the branched model, ?6.71 and 1.52?mL/min/kg. In conclusion, the HR?+?arm-leg ACC model should, when feasible, be preferred in wearable systems for WM estimation.

Practitioner Summary: Work with high energy demand can impair employees’ health and life quality. Three models were evaluated for estimating work metabolism during simulated tasks. The model combining heart rate, wrist- and thigh-worn accelerometers showed the best accuracy. This is, when feasible, suggested for wearable systems to assess work metabolism.     

基于STM32单片机的大学生体能监测仪设计与实现

体能监控仪作为生命体征监测设备,对于辅助大学生完成体能训练有很大帮助;基于STM32单片机技术,设计开发集成了多种传感器的一种大学生体能监测装备,它能够有效的检测包括心率检测、人体的步数、运动圈速、消耗卡路里等信息;该设计采用了STM32作为主控芯片,采用模块化的设计思路;在系统硬件设计方面,设计了包括STM32控制系统、心率获取电路、三轴传感器电路、显示电路以及按键电路等;同时将软件模块拆分成了初始化子程序、心率获取子程序,步数获取子程序,显示子程序等;Proteus仿真结果显示,使用STM32单片机技术设计的体能监测系统,能够运行稳定,测量心率范围60次/min~180次/min,可在心率异常时报警,同时检测步数的准确率达98%,满足体能监测任务需要,实验结果符合预期;为STM32单片机在体育运动研究信息化中应用提供参考。