水源热泵中央空调控制与网络监控系统

水源热泵中央空调控制与网络监控系统主要是针对现代使用的一种新型高效、节能、环保的空调进行的原理分析、系统设计和控制设计,实现空调系统的智能化控制,同时该系统运用现代高科技、高速度的网络技术对系统进行网络监控,打破了原有的工业远程监控的模式,在工业自动化领域和计算机网络领域均是一种创新和突破。该系统具有环保、节能、可靠性高、自动化程度高等特点,具有很高的经济效益和社会效益,应用前景广阔。     

沈从文与服饰史研究的三重证据法

沈从文的《中国古代服饰研究》实际上已意识到服饰史料的三个种类:实物、图像、文献,惜其未能详尽其言。本文从其中分析出最适合服饰史研究的三重证据法,并结合罗兰·巴特对于服饰符号体系的三分进行了进一步阐述,参照西方服装史的研究,提出运用三重证据法研究中国服饰史的重要意义。     

非间断软件回归测试模型研究

软件测试是开发过程的重要环节。回归错误在开发过程中严重影响着开发的效率,其隐匿特性也使得测试比较困难。因此,本文提出一种非间断测试的模型,用于加强对回归错误的管理,节约不必要的无谓工作时间,提高软件开发的效率。这种模型对用户开发行为进行模拟和推测,在经过大量的数据训练后,寻找测试行为、错误发生等开发动作的捕获点,从而找到最佳的测试策略。在不影响开发人员工作的前提下,可对当前最新的代码进行测试,最大程度上避免回归错误长期隐藏在前期代码中,保持整个开发过程的稳步前进。     

AU-aware Algorithm for 3D Facial Reconstruction

As a critical task in computer vision and animation, 3D face reconstruction can provide 3D model structures and rich semantic information for multi-modal facial applications. However, monocular 2D facial images lack depth information and the parameters of the predicted facial model are not reliable, which causes poor reconstruction results. We propose to employ facial Action Unit (AU) and key facial points which are highly correlated with model parameters as a bridge to guide the regression of model-related parameters and thus solve the ill-posed monocular face reconstruction. Based on existing face reconstruction datasets, we provide a complete semi-automatic labeling scheme for facial AUs and construct a 300W-LP-AU dataset. Furthermore, a 3D face reconstruction algorithm based on AU awareness is put forward to realize end-to-end multi-tasking learning and reduce the overall training difficulty. Experimental results show that the algorithm can improve the face reconstruction performance, with high fidelity of the rebuilt facial model.     

强流管辐射剂量率点灵敏度计数值误差范围确定

主要介绍了盖革-米勒计数管(GM计数管)中一种强流管的工作原理,强流管辐射剂量率点灵敏度计数率误差范围确定,以及误差范围如何计算,为以后的强流管产品生产和源室主管提供一些参考.     

工程力学点的合成运动教学研究

文章从解决点的合成运动问题出发,重点介绍了加深对概念、定理理解的教法及分析问题的技巧,通过实例阐明了分析问题、解决问题的方法。     

同轴式双空心抽油杆下入深度设计方法

同轴式双空心抽油杆加热系统可有效解决高凝油井井筒易结蜡、稠油井产液黏度较高的问题,但考虑油井生产效率、开采成本及综合的经济效益,需要计算出最佳的抽油杆下入深度。以井口出油温度最优为目标,同轴式双空心抽油杆下入深度、循环水进口温度为约束条件,建立了井口出油温度C计算模型。利用该模型进行求解时,先用迭代法进行同轴式双空心抽油杆下入深度优化,然后在优化结果基础上进行抽油机载荷校核。建立的井口出油温度计算模型及同轴式双空心抽油杆下入深度确定方法,在现场13口油井进行了应用。结果表明,该方法避免了以前设计人员凭经验确定抽油杆下深的弊端,可靠性更高,且有效时率平均提高14.1百分点,既满足了生产需要又节省了油井开发成本。      

热重法确定MMH微晶中各种水分的相对含量

借助热分析仪对MMH微晶进行了TG和DTG分析,研究了MMH微晶中各种水分的相对含量。提出MMH微晶中存在4种水分,即自由水、松散吸附水和紧密吸附水、结晶水和羟基水,给出了MMH微晶的完整表达式,即 MgAl_(0.965)(OH)_(4.75)Cl_(0.145·1.70)H_2O。     

IC工厂水的回收与回用

针对不同的芯片工厂类型的用水特点,提出不同的纯水回用方法。     

Blocking the PCNA/NKp44 Checkpoint to Stimulate NK Cell Responses to Multiple Myeloma

Simple SummaryMembrane-associated PCNA is expressed on the surface of human MM cell lines and primary MM cells. Mab 14-25-9 interacts with membrane-associated PCNA and blocks its binding to NK-expressed NKp44, thus activating NK function. We showed that mAb 14-25-9 can serve as an immune checkpoint blocker, enhancing the function of NK cells on target human MM cell lines and primary cells.AbstractMultiple Myeloma (MM) is a devastating malignancy that evades immune destruction using multiple mechanisms. The NKp44 receptor interacts with PCNA (Proliferating Cell Nuclear Antigen) and may inhibit NK cells’ functions. Here we studied in vitro the expression and function of PCNA on MM cells. First, we show that PCNA is present on the cell membrane of five out of six MM cell lines, using novel anti-PCNA mAb developed to recognize membrane-associated PCNA. Next, we stained primary bone marrow (BM) mononuclear cells from MM patients and showed significant staining of membrane-associated PCNA in the fraction of CD38⁺CD138⁺ BM cells that contain the MM cells. Importantly, blocking of the membrane PCNA on MM cells enhanced the activity of NK cells, including IFN-γ-secretion and degranulation. Our results highlight the possible blocking of the NKp44-PCNA immune checkpoint by the mAb 14-25-9 antibody to enhance NK cell responses against MM, providing a novel treatment option.