有限厚度带键槽接缝单元及接缝对混凝土坝应力的影响

本文给出了有限厚度的带键槽三维实体接缝单元，它可以较好地反映接缝附近的应力和接触条件。文中分析了接缝的初始间隙问题，分析结果表明，经过灌浆以后，由于浆体收缩而产生的初始间隙是很小的，一般可以忽略。文中还分析了灌浆质量对坝体应力的影响，分析结果表明，只要浆体灌进了接缝，虽然浆体质量差一些，带有键槽的接缝对坝体应力和变形的影响是很小的。本文最后分析了横缝不抗拉对拱坝应力的影响，分析结果表明，这个问题与横缝受拉深度a和横缝间距L的比值a/L有关，a/L越大，横缝不抗拉对坝体应力的影响越大，此外，还与坝体厚度及气候条件有关。     

基于响应曲面模型的泵站进水池参数优化方法研究

泵站进水池的结构参数,特别是吸水喇叭管参数取值对泵站整体流态影响很大。本文基于响应曲面模型和CFD数值模拟,以垂直布置的吸水喇叭管悬空高、后壁距和淹没深度为设计变量,以进水池压力场、速度场和涡量场评价指标的加权函数为目标函数,进行2因素和3因素的优化设计分析。研究结果表明,变量之间对进水池流态的交互作用较大,淹没深度对最优悬空高、后壁距的影响不可忽略,且淹没深度与悬空高的交互作用(P=0.0019)较其与后壁距的交互作用(P=0.0696)大。针对本文垂直布置型式的吸水喇叭管,推荐最优参数组合是悬空高0.77 D,后壁距0.37 D,淹没深度2.19 D。在该组合下实际值与预测值误差不大于4.82%,与泵站设计规范推荐值相比,其计算域水力损失降低0.98%,流速分布均匀度提高5.92%,机组纵剖面涡量分布特征值降低3.1倍,大大改善了进水池的流态。这表明所建立的二次多项式响应面模型能够较精确地表示设计变量与目标函数之间的关系,基于响应曲面模型的优化设计方法可有效用于泵站进水流场的流态优化。     

通道间隙对等径角轧制AZ31镁合金板材组织与性能的影响

研究了不同通道间隙下,AZ31镁合金板材在等径角轧制过程中晶体取向的演化特征以及通道间隙对其显微组织和力学性能的影响.X射线衍射分析表明在等径角轧制过程中,随着通道间隙的减小,晶体取向变化加大,(0002)基面取向减弱.等径角轧制后,孪晶明显增多,且随着通道间隙的减小,孪晶数量逐渐增多.单向拉伸试验表明,等径角轧制后的板材,其变形行为和力学性能存在明显的各向异性特征,与等径角轧制前的板材相比,在轧向其屈服强度明显降低由轧制前的240MPa降至155MPa,抗拉强度略有增加,但随着通道间隙的减小,断裂延伸率略有增大;在横向其屈服强度和抗拉强度均增大,随着通道间隙的减小,屈服强度和抗拉强度略有减小,但断裂延伸率增大.     

传动间隙引起的电动舵机自振荡现象研究

应用描述函数法对传动间隙引起的电动舵机自振荡现象进行了研究。从机理上阐明了在空载状态下,间隙引起的电动舵机自振荡现象产生的原因,分析了该自振荡频率和幅值的影响因素,以及不同控制策略对该自振荡的影响。最终对一个工程实例进行了分析,通过仿真模拟出与工程实例完全一样的响应曲线,从而证明了理论的正确性。     

Planetary gear load sharing of wind turbine drivetrains subjected to non‐torque loads

An analytical formulation was developed to estimate the load‐sharing and planetary loads of a three‐point suspension wind turbine drivetrain considering the effects of non‐torque loads, gravity and bearing clearance. A three‐dimensional dynamic drivetrain model that includes mesh stiffness variation, tooth modifications and gearbox housing flexibility was also established to investigate gear tooth load distribution and non‐linear tooth and bearing contact of the planetary gears. These models were validated with experimental data from the National Renewable Energy Laboratory's Gearbox Reliability Collaborative. Non‐torque loads and gravity induce fundamental excitations in the rotating carrier frame, which can increase gearbox loads and disturb load sharing. Clearance in the carrier bearings reduces the bearing stiffness significantly. This increases the amount of pitching moment transmitted from the rotor to the gear meshes and disturbs the planetary load share, thereby resulting in edge loading. Edge loading increases the likelihood of tooth pitting and planet‐bearing fatigue, leading to reduced gearbox life. Additionally, at low‐input torque, the planet‐bearing loads are often less than the minimum recommended load and thus susceptible to skidding. Copyright © 2014 John Wiley & Sons, Ltd.     

Numerical investigation of tip clearance effects in an axial transonic compressor

Numerical investigations of the Darmstadt transonic single stage compressor (DTC), in the Rotor1-Stator1 configuration, aimed at advancing the understanding of the effect of different rotor tip gaps and transition modelling on the blade surfaces are presented. Steady three dimensional Reynolds Averaged Navier Stokes (RANS) simulations were performed to obtain the flow fields for the different configurations at different operating conditions using the RANS-Solver TRACE. The stage geometry and the multi-block structured grid were generated by G3DMESH and a grid sensitivity analysis was conducted. For the clearance gap region, a fully gridded special H-grid was chosen. Comparisons were made between the flow characteristic at design speed, representative for a transonic flow regime, and at 65% speed, representative for a subsonic flow regime. The computations were used to analyse the flow phenomena through the tip clearance region for the different configurations and their impact on the performance of the compressor stage.     

叶顶间隙对超临界二氧化碳向心透平性能的影响

为探究叶顶间隙对超临界二氧化碳向心透平机性能的影响,以某超临界二氧化碳向心透平为例,设置不同叶顶间隙,利用计算流体动力学(CFD)仿真软件进行数值模拟。结果表明:当径向间隙等于轴向间隙时,间隙尺寸在0.1~0.5 mm范围内,叶顶间隙与叶轮出口叶高的比值每增大1%,总-静效率降低1.07%左右。当径向间隙不等于轴向间隙时,轴向间隙每增大1%,总-静效率降低0.146%左右,径向间隙每增大1%,总-静效率大约降低0.362%;径向间隙对于透平性能的影响远大于轴向间隙,叶顶间隙在0.1~0.5 mm范围内时,径向间隙对总-静效率的影响约为轴向间隙的2倍。     

月柿提取物体外抗氧化活性研究

目的以月柿提取物为原料,研究其对2,2-联苯基-1-苦基肼基(1,1-diphenyl-2-picrylhydrazyl,DPPH)自由基的清除能力,并测定其多酚类物质没食子酸的含量。方法检测波长为518 nm,反应时间为40 min条件下,以IC_(50)值(清除率为50%时,抗氧化剂的浓度值)作为抗氧化能力评价指标,并采用高效液相色谱法测定其没食子酸含量。结果月柿提取物对于DPPH自由基有良好的清除作用,其IC50值为0.1868 mg/mL,与常用抗氧化剂作用相当,且月柿提取物中没食子酸含量为1.65 g/kg。结论月柿提取物具有很强抗氧化活性,作为化妆品及功能性食品原料有广阔的开发前景。     

A Clearance Period after Soluble Lead Nanoparticle Inhalation Did Not Ameliorate the Negative Effects on Target Tissues Due to Decreased Immune Response

The inhalation of metal (including lead) nanoparticles poses a real health issue to people and animals living in polluted and/or industrial areas. In this study, we exposed mice to lead(II) nitrate nanoparticles [Pb(NO₃)₂ NPs], which represent a highly soluble form of lead, by inhalation. We aimed to uncover the effects of their exposure on individual target organs and to reveal potential variability in the lead clearance. We examined (i) lead biodistribution in target organs using laser ablation and inductively coupled plasma mass spectrometry (LA-ICP-MS) and atomic absorption spectrometry (AAS), (ii) lead effect on histopathological changes and immune cells response in secondary target organs and (iii) the clearance ability of target organs. In the lungs and liver, Pb(NO₃)₂ NP inhalation induced serious structural changes and their damage was present even after a 5-week clearance period despite the lead having been almost completely eliminated from the tissues. The numbers of macrophages significantly decreased after 11-week Pb(NO₃)₂ NP inhalation; conversely, abundance of alpha-smooth muscle actin (α-SMA)-positive cells, which are responsible for augmented collagen production, increased in both tissues. Moreover, the expression of nuclear factor κB (NF-κB) and selected cytokines, such as tumor necrosis factor alpha (TNFα), transforming growth factor beta 1 (TGFβ1), interleukin 6(IL-6), IL-1α and IL-1β , displayed a tissue-specific response to lead exposure. In summary, diminished inflammatory response in tissues after Pb(NO₃)₂ NPs inhalation was associated with prolonged negative effect of lead on tissues, as demonstrated by sustained pathological changes in target organs, even after long clearance period.     

Circulating Insulin-Like Growth Factor I is Involved in the Effect of High Fat Diet on Peripheral Amyloid β Clearance

Obesity is a risk factor for Alzheimer’s disease (AD), but underlying mechanisms are not clear. We analyzed peripheral clearance of amyloid β (Aβ) in overweight mice because its systemic elimination may impact brain Aβ load, a major landmark of AD pathology. We also analyzed whether circulating insulin-like growth factor I (IGF-I) intervenes in the effects of overweight as this growth factor modulates brain Aβ clearance and is increased in the serum of overweight mice. Overweight mice showed increased Aβ accumulation by the liver, the major site of elimination of systemic Aβ, but unaltered brain Aβ levels. We also found that Aβ accumulation by hepatocytes is stimulated by IGF-I, and that mice with low serum IGF-I levels show reduced liver Aβ accumulation—ameliorated by IGF-I administration, and unchanged brain Aβ levels. In the brain, IGF-I favored the association of its receptor (IGF-IR) with the Aβ precursor protein (APP), and at the same time, stimulated non-amyloidogenic processing of APP in astrocytes, as indicated by an increased sAPPα/sAPPβ ratio after IGF-I treatment. Since serum IGF-I enters into the brain in an activity-dependent manner, we analyzed in overweight mice the effect of brain activation by environmental enrichment (EE) on brain IGF-IR phosphorylation and its association to APP, as a readout of IGF-I activity. After EE, significantly reduced brain IGF-IR phosphorylation and APP/IGF-IR association were found in overweight mice as compared to lean controls. Collectively, these results indicate that a high-fat diet influences peripheral clearance of Aβ without affecting brain Aβ load. Increased serum IGF-I likely contributes to enhanced peripheral Aβ clearance in overweight mice, without affecting brain Aβ load probably because its brain entrance is reduced.