机载红外诱铒弹光谱辐射特性研究

描述了机载红外诱铒弹的光谱辐射特性,给出了１．３－３μｍ,３－５μｍ,８－１４μｍ波段的光谱辐射曲线及时域性曲线,对红外诱耳弹的对抗特性及其改进方法进行了分析。     

一种红外烟幕三维建模仿真方法

根据红外烟幕的遮蔽原理, 结合红外烟幕消光模型和扩散模型建立红外烟幕三维空间的透过率模型。针对传统烟幕遮蔽效果仿真方法的局限性, 提出一种三维空间透过率的仿真方法,并对其进行数值计算与仿真验证。研究结果表明, 探测器观察到的目标图像是多层透过率叠加的结果, 遮蔽效果优于传统方法, 对工程应用更具意义。     

基于GMM-UBM模型的说话人辨识研究

为了进一步提高基于传统的GMM模型的说话人辨识的识别率,引入了GMM-UBM模型,并且在特征提取方面采用多种特征参数组合来代替单一特征参数,以提高有效特征维数来弥补特征样本的不足,同时在说话人辨识的端点检测部分,用基于MFCC相似度和谱熵的端点检测方法来代替传统的基于短时能量和过零点的方法,以解决其对含噪语音检测不准确而影响说话人辨识的问题。实验表明,与传统的GMM模型相比,GMM-UBM模型能够有效地提高说话人辨识的性能,并且使用组合特征参数和利用基于MFCC相似度和谱熵的端点检测方法都可以进一步提高说话人辨识的性能。     

基于可见光-近红外新光谱特征和最优组合原理的大麦叶片氮含量监测

提出新的作物冠层叶片氮含量(LNC)高光谱遥感监测方法,以对氮素要求较高的大麦LNC监测为例,利用田间实测数据,从可见光－近红外区域的高光谱反射曲线中提取包含丰富多波段信息的斜率、夹角等新型特征参数,应用组合预测领域中的权重最优组合原理及其算法,实现对作物LNC的高光谱监测.研究表明,提出的高光谱反射曲线斜率和夹角等新型特征参数与作物LNC显著相关,并具有较好的定量响应关系,其中关键斜率参数(Kre/Kpb)和Kpb以及夹角参数(Aδ/Aα)和(Aδ/Aθ)较好地描述了LNC的动态变化; 而权重最优组合分析则表明(Kre/Kpb)和Knir1两个参数的组合最能响应LNC的光谱信息,有助于增强监测的稳定性并提高估测的精度.     

复合寻的制导信息融合技术分析

复合寻的制导技术是当今世界各国竞相发展的精确制导技术之一 ,如何实现多模探测器的信息融合也已成为世界各国研究的重要课题。本文以毫米波雷达 /红外成像传感器复合为背景较系统地分析了复合寻的制导信息融合的机理、信息融合的方法和关键技术 ,并且展望了未来复合寻的制导信息融合技术的发展前景     

飞行控制计算机的设计及其接口仿真

介绍了一种用于简易制导炸弹的飞行控制计算机设计原理;阐述了在静态环境下仿真飞行控制计算机的工作流程和调试飞行控制计算机外围接口的方法.     

有线无线组合通信的便携式哨兵报警对讲系统

针对哨兵离开哨位处置突发警情时哨兵与值班室的联系中断这一问题,采用以有线通信和无线通信组合的方式设计了便携式哨兵报警对讲系统,实现哨兵离开哨位时与值班室的语音对话,同时实现哨兵遇到紧急情况无法进行语音对话时的紧急报警以及当哨兵遭到袭击倒地的自动检测报警。     

对微弱激光辐射的探测

由于面临越来越严重的激光制导武器的威胁 ,对来袭威胁进行早期预警日趋重要。概要介绍了微弱激光辐射探测技术国外研究现状及发展趋势。对微弱激光辐射探测关键技术进行了研究探讨。     

Smart Injectable Hydrogels for Cancer Immunotherapy

Hydrogels, a class of materials with a 3D network structure, are widely used in various fields especially in biomedicine. Injectable hydrogels could facilitate the encapsulation and controlled release of small molecular drugs, macromolecular therapeutics, and even cells. With the rapid development of cancer immunotherapy, such injectable hydrogels have attracted wide attention for local immunomodulation to boost systemic anticancer immune responses, realizing more effective immunotherapy at lower doses. The latest progresses in the development of various smart injectable hydrogels for cancer immunotherapy are summarized here. Although applied locally, such injectable hydrogels can activate systemic antitumor immune responses, safely and effectively inhibiting the tumor metastasis and recurrence. Moreover, it is discussed how injectable hydrogel‐based cancer immunotherapy would contribute to the development of next generation of cancer treatment together with their potential for clinical translation.     

Biodegradable Nanoscale Coordination Polymers for Targeted Tumor Combination Therapy with Oxidative Stress Amplification

Nowadays various inorganic nanoparticles that generate highly reactive hydroxyl radical ( · OH) on the basis of Fenton‐like catalytic activity of metal ions have been designed for chemodynamic therapy. However, the high level of adaptive antioxidants [glutathione (GSH)] in cancer cells could effectively consume · OH to compromise the treatment efficiency and biosafety of these inorganic nanoparticles, and this is a general concern in chemodynamic therapy. Herein, a new biodegradable nanoscale coordination polymer (NCP) is developed by integration of cisplatin prodrug (DSCP) and iron (III) ions through a reverse microemulsion method. The DSCP in the NCPs could react with GSH to release free cisplatin, while the iron (III) ions could be reduced by GSH into iron (II) to enable Fenton reaction, subsequently leading to amplified intracellular oxidative stress. After surface modification of polyethylene glycol (PEG) and cyclo[Arg‐Gly‐Asp‐D‐Phe‐Lys(mpa)] peptide (cRGD), Fe‐DSCP‐PEG‐cRGD shows an excellent targeting effect against α_vβ₃‐integrin overexpressed tumor cells. Furthermore, Fe‐DSCP‐PEG‐cRGD enables significant chemo and chemodynamic therapy with dramatically enhanced therapeutic efficiency in comparison to relative monotherapies. Importantly, Fe‐DSCP‐PEG‐cRGD could be efficiently cleared out from mice through feces and urine postinjection 7 days. The NCP presented in this work is simple and economical, which shows great biodegradability and biosafety for potential clinical translation.