Cooperation between memory systems: Acetylcholine release in the amygdala correlates positively with performance on a hippocampus-dependent task.

The present experiment examined the relationship between release of acetylcholine (ACh) in the amygdala and performance on a hippocampus-dependent spatial working memory task. Using in vivo microdialysis, the authors measured ACh release in rats during testing on a spontaneous alternation task. Amygdala ACh release was positively correlated with performance on the hippocampus-dependent task. These findings suggest that activation of the amygdala promotes processing in other neural systems important for learning and memory. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Preparation and characterization of chitosan‐based dispersions

Complexation of chitosan in aqueous solutions by low molecular weight electrolytes is one of the simplest methods for the preparation of aqueous chitosan dispersions. In this work, the influence of storage time, sulfate concentration, method of preparation and surfactant content on some properties of the resultant chitosan dispersions (turbidity, viscosity and zeta potential) was analyzed. Turbidimetry was adequate to monitor the formation of particles, while viscometry was suitable to monitor changes in the dispersing phase. An analysis of the properties of these systems, mainly in terms of particle–particle and macromolecule–macromolecule interactions was carried out. Copyright © 2004 Society of Chemical Industry     

Rheological and drug‐release behaviour of a scleroglucan gel matrix at different drug loadings

The aim of this study was to investigate the drug‐loading effects on release and mechanical properties of a scleroglucan gel, with the intention of considering them in delivery systems formulations. The rheological and kinetic properties of a 2 % w/w scleroglucan gel matrix loaded with 0, 0.02, 0.04, 0.06, 0.2 and 0.4 % w/w of theophylline (Th, used as a model drug) were investigated. Rheological measurements were performed in a controlled‐stress rotational‐shear rheometer under isothermal conditions. For theophylline release from the gel a flat Franz cell was used and the kinetic parameters were derived applying a semi‐empirical power law. The influence of scleroglucan molar weight on kinetic and rheological behaviour was also studied. Results suggest two possible effects of drug loading on the gel network: in the 0.04–0.06 % w/w Th range a plasticizing effect and in the 0.2–0.4 % w/w Th range a rigidization effect. In the first range mentioned, the changes in the gel structural properties tested by means of rheological measurements are coincident with changes in drug‐release kinetics. Copyright © 2005 Society of Chemical Industry     

交联透明质酸的降解及其释药性能

用己二酸二酰肼（ADH）对透明质酸（HA）进行化学修饰，制备交联透明质酸（HA-ADH）薄膜。粘度法测试表明HA-ADH是一种可降解的生物材料，并且与HA相比，HA．ADH的降解速率减慢。在此基础上，研究了以疏水性的替硝唑（TDZ）和亲水性的头孢唑啉钠（CEZ）为模拟药物的HA-ADH药物载体薄膜的释药性能。紫外-可见（UV-Vis）吸收光谱检测表明，HA-ADH是一种疏水性药物TDZ的优良缓释制荆，这是由于TDZ的疏水性和HA-ADH薄膜的缓慢溶胀和降解性能的结合而得到的，药物的释放主要受扩散机制控制。     

相变储能材料研究进展

综述了固-固相变储能材料（s-S PCMs：sofid-solid phase change materials）、固-液相变储能材料（s-1 PCMs：solid—liquid phase change materials）的主要优缺点，并主要介绍了以下2种封装方式：（1）PCMs与基体材料复合制成定型PCMs，包括：与有机高分子材料机械共混、用无机多孔材料封装；（2）PCMs微囊化。此外，还分析了PCMs的主要应用领域及PCMs的主要研究方向。     

应用SPC技术对机械零件加工过程的管理和控制

介绍了SPC(统计过程控制)技术原理，以某传动轴外径φ45 0.50^0.90 mm为控制对象，提出应用SPC技术，对机械零件加工过程进行管理和控制，从而达到过程失控预警、过程不断改进、过程能力不断提高的目的，继而保证产品质量的稳定和不断提高。     

控轧技术在H型钢生产中的应用

根据钢板的控轧经验，结合H型钢轧制的特点分析控轧在轧制中运用的具体问题，制定H型钢控轧工艺方案。介绍了实际应用情况，并提出改进的措施。     

受控离散事件过程（CDEP）的一种代数分析方法

本文在文［１～３］的基础上，提出了受控离散事件过程（ＣＤＥＰ）的一种代数分析方法，弥补了Ｒａｍａｄｇｅ和Ｗｏｎｈａｍ［１～３］的理论对具体系统的应用缺乏可操作性的缺陷，使得对ＣＤＥＰ动态过程的分析变得更为直观，同时也使控制器的设计过程更具可操作性．     

反向回转双激振器振动机控制同步的理论研究

本文对两激振器作反向回转的振动机控制同步进行了理论研究和计算机仿真。推导出了考虑质心偏移时两主轴的转矩差方程，在此基础上建立了控制系统的数学模型，设计了具有鲁棒性的非线性变结构滑模控制器．仿真结果表明，控制同步不仅可以消除由质心偏移、电机特性差等原因引起的稳态相位差，同时还能大大降低瞬态相位差，从而使机体的振动方向保持不变，减小起、制动过程中机体的摇摆振动．