Solubilization of unilamellar liposomes by betaine-type zwitterionic/anionic surfactant systems

The mechanisms governing the solubilizing interactions between zwitterionic/anionic mixed surfactant systems at different molar fractions of the zwitterionic surfactant (X_zwitter) and neutral or electrically charged unilamellar liposomes were investigated. The mixed systems were formed by N-dodecyl-N,N-dimethylbetaine and sodium dodecyl sulfate in the presence of piperazine-1,4-bis-(2-ethanesulfonic acid) buffer at pH 7.20. Unilamellar liposomes formed by egg phosphatidylcholine, in some cases together with stearylamine or phosphatidic acid, were used. Solubilization was detected as a decrease in static light-scattering of liposomes. Two parameters were regarded as corresponding to the effective surfactant/lipid molar ratios (Re) at which the surfactant system (i) saturated the liposomes, Re_sat, and (ii) led to a total solubilization of liposomes, Re_sol. From these parameters the bilayer/aqueous medium surfactant partition coefficients for the saturation (K_sat) and complete bilayer solubilization (K_sol) were determined. When X_zwitter was 0.40, The Re and K parameters showed a maximum, whereas the critical micellar concentration (CMC) of these systems exhibited a minimum, regardless of the electrical charge of bilayers. Given that the ability of the surfactant systems to saturate or solubilize liposomes is inversely related to the Re_sat and Re_sol parameters, these capacities appear to be directly correlated with the CMC of the mixed systems. The similarity of both K_sat and K_sol (particularly for X_zwitter=0.2–0.8) suggests that a similar partition equilibrium governs both the saturation and the complete solubilization of bilayers, the free surfactant concentration (S_a,S_b), remaining almost constant with similar values to the CMC for each mixed system studied.     

桩土物理模型及结构—桩—土相互作用

本文将工程中常用的密集打桩土体模拟为正交各向异性弹性体。建立了刚性基础-桩-土这一空间相互作用系统的模型。根据圆柱体柱坐标的极点条件。分别选取了两组位移函数来表征桩基和土的位移,并用子区间法分析了结构-桩-土系统的相互作用地震反应。     

Ultrasonic study of molecular association of poly(vinyl chloride) solution in tetrahydrofuran

Ultrasonic absorption, velocity, adiabatic compressibility, relaxation time and relaxation amplitude measurements are reported on poly(vinyl chloride) (PVC) solution in tetrahydrofuran (THF) using pulsed ultrasonic apparatus operating at 2 MHz and 313 K. Results show a linear increase of velocity. density, viscosity, absorption coefficient, relaxation time and relaxation amplitude values with the increase of PVC concentration in THF. In contrast the compressibility decreases with increasing PVC concentration. This suggests interaction between PVC and THF molecules.     

基于AOTF的在线红外光谱测量系统

介绍了一种新型的红外光谱测量系统，它由准直发射系统和聚焦接收系统两大部分组成，以声光可调谐滤光器（AOTF）为色散元件，连续改变AOTF的驱动频率就能实现快速波长扫描，达到实时测量目的。该系统具有结构简单、测量快速等特点，可用于在线有害气体检测和红外光谱分析。实验表明，系统光谱测量范围2．5－5μm，光谱分辨力为10nm。     

缺陷交互作用对陶瓷半导体导电性能的影响

本文借助于缺陷化学反应过程，分析了陶瓷半导体内缺陷间的交互作用，得到了陶瓷半导体实验研究的三个重要启示：（1）强还原（或氧化）或施主（或受主）掺杂对同一样品不能同时起到最佳效果；（2）本征原子空位对施主或受主的补偿导致电导率的非线性增长；（3）缺陷的缔合降低了半导化杂质的有效浓度，从而使电导性能发生异常变化。     

Automated Support for Building and Extending Expert Models

Building a knowledge-based system is like developing a scientific theory. Although a knowledge base does not constitute a theory of some natural phenomenon, it does represent a theory of how a class of professionals approaches an application task. As when scientists develop a natural theory, builders of expert systems first must formulate a model of the behavior that they wish to understand and then must corroborate and extend that model with the aid of specific examples. Thus there are two interrelated phases of knowledge-base construction: (1) model building and (2) model extension. Computer-based tools can assist developers with both phases of the knowledge-acquisition process. Workers in the area of knowledge acquisition have developed computer-based tools that emphasize either the building of new models or the extension of existing models. The PROTÉGÉ knowledge-acquisition system addresses these two activities individually and facilitates the construction of expert systems when the same general model can be applied to a variety of application tasks.     

High temperature low cycle fatigue

Fatigue at high temperature is a complex phenomenon as it is influenced by a number of time-dependent processes which become important at elevated temperatures. These processes include creep, oxidation, phase instabilities and dynamic strain ageing (DSA), acting either independently or synergistically influence fatigue behaviour, often lowering the fatigue life. Current design approaches employ linear summation of fatigue and creep damage with suitable factors on permissible damage to take care of uncertainties in interaction between cyclic and time-dependent processes. It is, therefore, important to develop a deeper understanding of the processes that occur during high temperature fatigue so that realistic life predictions could be made. Results on the high temperature fatigue behaviour of austenitic stainless steels, ferritic steels and nickel base alloys are presented here. The important mechanisms of interaction of high temperature time-dependent processes with fatigue under various conditions are discussed in detail. Emphasis is placed on cyclic stress response, fatigue life, deformation substructure and fracture behaviour. This is followed by a review of important life prediction techniques under combined creep-fatigue loading conditions. Life prediction techniques considered here include linear damage summation, strain range partitioning, ductility exhaustion approach, frequency modified and frequency separation methods, techniques based on hysteresis energy and damage rate models, and methods based on crack-cavitation interation models.     

严格环境管理提高环境意识

环境伴随着经济的发展越来越体现了它的重要性,全社会应重视环境、保护环境,以预防为主,加强综合治理,使我们的天更蓝、水更净、草更绿,到处充满着春的意境.     

A simple correlation for estimating viscosities of solutions of salts in aqueous,non-aqueous and mixed solvents applicable to high concentration,temperature and pressure

A new correlation is proposed to correlate the viscosities of salt solutions in aqueous, non-aqueous solvents and their mixtures. The correlation involves two parameters i.e. solvation number and ion-solvent interaction coefficient, which are well-documented quantities in the literature. The proposed correlation has been examined on the experimental viscosity data of salt solutions in aqueous, non-aqueous and their mixtures up to 473 K and 31 MPa pressure. The salts with various ionic charges were employed for testing the proposed correlation. Several non-aqueous solvents like dimethyl sulphoxide, alcohols and formamide were included for the data regression. The viscosities of these solutions can be correlated to within 0.7%.     

地基基础与上部结构共同作用和结构次生应力问题

本文考虑到上部结构与地基基础共同作用的事实,着重分析上部结构参与共同作用导致的内力重分布——次生应力问题。通过多个理论与实验的结果,对不同地基和基础条件下的次生应力进行了定量分析,探讨了造成次生应力的各种因素以及对建筑结构带来的危害。