基于人性化理念的商业建筑交通空间设计

本文以商业建筑交通空间为研究对象,从物理环境、景观环境、心理环境等方面入手,强调人性化理念指导下的交通空间设计研究是科学有效的设计途径。     

人性化理念在城市规划中的应用探索

根据多年从事建筑管理的体会与经验,提出了城市规划与设计中人性化理念的应用思路,目的在于探讨在新的历史时期,人性化设计理念如何在宏观上为我国发展中的城市规划与设计建设提供应用的帮助与借鉴。     

浅谈办公空间环境设计中的几个重要因素

结合办公空间环境设计的特点,阐述了空间规划、家具、照明、整体风格等是办公空间环境设计中的几个重要因素,就设计中如何统一整合考虑这些因素作了探讨,并对办公空间环境设计的发展趋势作出简述,以使办公空间环境实现人性化、生态化。     

Expression and Characterization of Bioactive Recombinant Human α-Lactalbumin in the Milk of Transgenic Cloned Cows

Improvement of the nutritional value of cow milk with transgenic expression of recombinant human α-lactalbumin (α-LA) has been previously attempted. However, the detailed characterization of the recombinant protein and analysis of the transgenic milk components are not explored yet. Here, we first report production of healthy transgenic cows by somatic cell nuclear transfer, in which expression of up to 1.55 g/L of recombinant human α-LA was achieved. The recombinant human α-LA was purified from transgenic milk and displayed physicochemical properties similar to its natural counterpart with respect to molecular weight, structure, and regulatory activity for β-1,4-galactosyltransferase. Additionally, no N-glycosylation was found in the recombinant human α-LA, whereas the endogenous bovine α-LA was glycosylated at the unusual site ⁷¹Asn-Ile-⁷³Cys. Compared with milk from nontransgenic cows, expression of the transgene did not materially alter milk composition, such as fat and protein content. Our research thus provides scientific evidence supporting the feasibility of humanizing cow milk.     

Advances in Transgenic Mouse Models to Study Infections by Human Pathogenic Viruses

Medical research is changing into direction of precision therapy, thus, sophisticated preclinical models are urgently needed. In human pathogenic virus research, the major technical hurdle is not only to translate discoveries from animals to treatments of humans, but also to overcome the problem of interspecies differences with regard to productive infections and comparable disease development. Transgenic mice provide a basis for research of disease pathogenesis after infection with human-specific viruses. Today, humanized mice can be found at the very heart of this forefront of medical research allowing for recapitulation of disease pathogenesis and drug mechanisms in humans. This review discusses progress in the development and use of transgenic mice for the study of virus-induced human diseases towards identification of new drug innovations to treat and control human pathogenic infectious diseases.     

俄罗斯地铁站地下空间人性化设计

通过对莫斯科地铁站地下空间设计的分析,总结了其人性化设计的经验,旨在对我国地铁站地下空间设计有一定的借鉴作用。     

人性化建筑外部空间的创造

文章从人对环境的感知,人在环境中的行为以及环境如何反映社会文化等方面对人性化建筑外部空间的创造进行探讨,最后提出人性化建筑外部空间的四项设计原则整体性,开放性,多样性和可识别性。     

地下车库内部空间环境的人性化设计浅析

我国地下车库建设在短短的十几年间经历了跨越式的发展,在缓解了城市停车压力的同时还存在着一些不足。从当前地下车库内部空间环境的现状入手,笔者通过大量的调研和实例分析,针对当前地下车库建设存在的问题,提出了人性化设计的重点和应对措施,并着重从健康物理环境的营造、行车道与停车位的布局、地面自然环境的渗透、艺术设计的运用、标识系统的完善等5个方面来进行深入细致的分析。注重功能实用的同时,也不应忽略其在建筑艺术和技术方面的要求,以此来提高地下车库的舒适性和利用率,为地下车库的设计和建设提供参考。     

武汉地铁2号线人性化设计

根据国内外的成熟经验,结合武汉实际情况,以及人们对人性化的思考,武汉地铁2号线主要从地铁与周边物业开发相结合、便捷的换乘、人性化的细节设计三个方面进行了研究,提出了安全、便捷、舒适的人性化设计理念。     

基于B／S的高校协同办公平台的设计与实现

为了提高高校办公效率,节约成本,对学生和教师进行人性化服务,在此基于微软的,Net平台,采用面向对象的方法,设计了一个三层架构的高效的协同办公平台。该平台消除了以往系统中的信息孤岛,能够使得高校各部门有效沟通,协同办公,有效提高资源的利用率和信息的共享,降低了成本,提高了服务质量。