多模态医学图像融合超声检查系统的设计与实现

超声检查系统所呈图像中缺乏三维结构信息,且商业的医学图像分析软件价格昂贵。为此,开发一款综合病灶部位的三维模型和二维超声图像各自特征以及对应空间关系的检查系统。基于开源的医学图像处理软件、商用的电磁定位系统和超声成像系统,在局域网环境下,遵循OpenIGTLink协议进行数据共享的超声检查系统。该系统主要由超声图像信息共享模块、超声图像显示模块、超声探头实时跟踪模块、2D/3D配准融合模块组成。实验结果表明,该系统可初步应用于临床教学和临床辅助诊断等领域,具有价格低廉、扩展性强、维护方便等优势。     

应用SPRI技术检测指纹上的化学品残留

介绍了表面等离子体共振成像（ SPRI）的原理,应用自行搭建的SPRI系统采集指纹图像,并分析其中的化学物残留。在实验中,测量了粘有TiO2颗粒的指纹和正常状态下的指纹的SPR吸收光谱,并进行比较分析。实验结果表明：指纹图像有较高的分辨率和对比度;通过对指纹图像进行SPR分析,获得其SPR图谱,能显著观察到其共振波长的变化,从而能实现对残留化学品的检测。     

FPIR实时快视成像方法

一维全极化综合孔径辐射计(Full Polarization Interferometric Radiometer,FPIR)是一种轻量化的高空间分辨率的综合孔径微波辐射计系统。基于综合孔径辐射计成像原理及X波段FPIR原理样机,提出一种快视成像方法:(1)对原始数据进行抽取和平均,降低实时处理运算量;(2)简化误差处理过程,进而利用傅立叶变换法和G矩阵法反演亮温。通过对FPIR原理样机的地面实验,验证了该实时快视成像方法的有效性。     

Creating Disk Images of Born Digital Content: A Case Study Comparing Success Rates of Institutional Versus Private Collections

Although libraries maintain collections of material on computer disks in climate controlled environments, a significant amount of digital heritage is in private collections. In this study we compared the outcomes of creating disk images of the State Library of South Australia’s born digital collections with those of a private collector to gauge the effect of long term storage conditions. The failure rates of both collections give cause for concern, and the results from the private collection are alarming.     

图谱法脑部MRI图像自动分割技术发展及应用

脑部MRI图像自动分割是计算机技术运用于医学上的一个典 型工作,脑部图像分割技术对于人类研究脑部疾病具有重要意义。虽然有一些非常广泛应用 的图像分割方法,如阈值法、区域增长法、聚类法等,但在脑部MRI图像分割中,这些方法 都 没有图谱法具有更为实际的医学研究与临床价值。本文回顾了脑部图像配准、分割的发展历 程,介绍了图谱分割算法的发展及基本原理,以及当前比较前沿的多图谱分割系统的组成和 应用。最后本文对图谱法脑部自动分割在实际临床医学中的应用前景作了总结和展望。     

Design of a printed log‐periodic dipole array antenna with high gain for millimeter‐wave applications

In this article, a V‐band printed log‐periodic dipole array (PLPDA) antenna with high gain is proposed. The antenna prototype is designed, simulated, fabricated, and tested. Simulation results show that this antenna can operate from 42 to 82 GHz with a fractional impedance bandwidth of 64.5% covering the whole V‐band (50–75 GHz). The antenna has a measured impedance matching bandwidth that starts from 42 to beyond 65 GHz with good agreement between the experimental and simulated results. At 50 and 65 GHz, the antenna has a measured gain of 10.45 and 10.28 dBi, respectively, with a gain variation of 2.6 dBi across the measured frequency range. The antenna prototype exhibits also stable radiation patterns over the operating band. It achieves side‐lobe suppression better than 17.26 dB in the H‐plane and better than 8.95 dB in the E‐plane, respectively. In addition, the cross‐polarization component is 18.5 dB lower than the copolarization with front‐to‐back ratio lower than 24.1 dB in both E‐ and H‐planes across the desired frequency range. Based on a comparison of performance among the reported work in the literature, we can say that the proposed PLPDA antenna is a proper candidate to be used in many applications at V‐band frequency. © 2014 Wiley Periodicals, Inc. Int J RF and Microwave CAE 25:185–193, 2015.     

磁共振多通道射频接收线圈性能评估

磁共振成像技术追求高信噪比和快速扫描。与单通道线圈相比,多通道线圈具有高信噪比、高分辨率和成像速度快的特点。为服务于射频线圈设计和制作,开发了基于磁共振k空间数据的多通道射频线圈性能评估软件。此软件可以准确方便地计算多通道线圈噪声耦合矩阵和信噪比。     

尾静脉注射方法考察Stearic-PEI/SPIO 纳米基因载体的基因转染性能及磁共振可视化效果研究

实验应用硬脂酸-聚乙烯亚胺包裹超顺磁氧化铁(Superparamagnetic Iron Oxide,SPIO)装载目的基因构建可视化 纳米复合物,进行 BABL/c 雌性小鼠体内磁共振成像实验、组织学检测,探讨其是否能够有效地介导体内基因表达以及 产生磁共振成像(Magnetic Resonance Imaging,MRI)效果。MRI 实验结果显示,对小鼠尾静脉注射复合物 0.5 小时后进 行磁共振扫描,与注射生理盐水的对照组相比实验组 T2 加权信号明显降低,信号强度仅为对照组的 35%;48 小时后, 实验组 T2 加权信号强度略有回升,但与对照组信号强度相比仍存在显著差异。组织学结果显示可视化基因纳米复合物 能够穿过血管内皮细胞进入肝脏组织,并释放 DNA 在细胞内成功表达,但基因表达效果较差。综合 MRI 成像及组织检 查实验结果可知,该纳米颗粒具有优良的 MRI 成像性能,但通过尾静脉注射方法基因转染效率较低。     

Strategies for processing diffraction data from randomly oriented particles

The high intensity of free-electron X-ray light sources may enable structure determinations of viruses or even individual proteins without the encumbrance of first forming crystals. This note compares two schemes of non-crystalline diffraction data collection that have been proposed: serial single-shot data from individual particles, and averaged cross-correlation data from particle ensembles. The information content of these schemes is easily compared and we show that the single-shot approach, although experimentally more challenging, is always superior in this respect. In fact, for 3D structure determination a constraint counting argument shows that the cross-correlation scheme suffers from data deficiency.     

Caustic imaging of gallium droplets using mirror electron microscopy

We discuss a new interpretation of mirror electron microscopy (MEM) images, whereby electric field distortions caused by surface topography and/or potential variations are sufficiently large to create caustics in the image contrast. Using a ray-based trajectory method, we consider how a family of rays overlaps to create caustics in the vicinity of the imaging plane of the magnetic objective lens. Such image caustics contain useful information on the surface topography and/or potential, and can be directly related to surface features. Specifically we show how a through-focus series of MEM images can be used to extract the contact angle of a Ga droplet on a GaAs (001) surface.