H∞ ALMOST DISTURBANCE DECOUPLING FOR MIMO BILINEAR SYSTEMS

The H_∞ almost disturbance decoupling problem is considered. In this paper, a nonlinear design is proposed to find a state feedback controller for bilinear systems. The closed‐loop system is internally stable and achieves disturbance attenuation in nonlinear H_∞ sense. We defined a special form of Lyapunov function, which is constructed in terms of one or a set of positive definite constant matrices. If, except of the origin of system, the corresponding polynomial of the positive definite matrix (or several polynomials relevant to the positive definite constant matrices) has (have) no zero on a given subset of state space, then we can construct a controller to solve our problem. It is found that the controller structure could be complicated, but is feasible in computation and may require optimization technique to search the solution. We consider both SIMO and MIMO cases with illustrated examples.     

Fluorescence in situ hybridization of three oncogenes on a leiomyoma

Using fluorescence in situ hybridization technique, expression of three oncogenes, C-myc, RARa, and cyclin-D was tested on a uterine leiomyoma. C-myc and RARa were amplified in approximately 30% and 90% of the cells, respectively. Numerous small signals of C-myc were indicative of the presence of double minutes. Amplification of RARa is being reported for the first time in a leiomyoma. Cyclin-D was normal in diploid cells while it was highly amplified in polyploid cells. Low levels of amplified C-myc and cyclin-D cells seem to be the reason for this tumor to be benign, while RARa could not be effective without the association of some other gene such as PML. Information presented here are significant toward developing new curative strategies such as gene-specific drugs and molecular manipulation to stop the activity of cancer gene. Further study may elucidate that how fibroids grow and maintain their rare benign nature.     

Analysis of singular stress fields at multi‐material corners under thermal loading

The scaled boundary finite‐element method is extended to the modelling of thermal stresses. The particular solution for the non‐homogeneous term caused by thermal loading is expressed as integrals in the radial direction, which are evaluated analytically for temperature changes varying as power functions of the radial coordinate. When applied to model a multi‐material corner, only the boundary of the problem domain is discretized. The boundary conditions on the straight material interfaces and the side‐faces forming the corner are satisfied analytically without discretization. The stress field is expressed semi‐analytically as a series solution. The stress distribution along the radial direction, including both the real and complex power singularity and the power‐logarithmic singularity, is represented analytically. The stress intensity factors are determined directly from their definitions in stresses. No knowledge on asymptotic expansions is required. Numerical examples are calculated to evaluate the accuracy of the scaled boundary finite‐element method. Copyright © 2005 John Wiley & Sons, Ltd.     

The generalized Riemann problem method for the shallow water equations with bottom topography

This paper extends the generalized Riemann problem method (GRP) to the system of shallow water equations with bottom topography. The main contribution is that the generalized Riemann problem method (J. Comput. Phys. 1984; 55 (1):1–32) is used to evaluate the midpoint values of solutions at each cell interface so that the bottom topography effect is included in numerical fluxes, and at the same step the source term is discretized with an interface method in which only mid‐point values are plugged in. This scheme is well balanced between the flux gradient and bottom topography when incorporating the surface gradient method (SGM) (J. Comput. Phys. 2001; 168 (1):1–25) into data reconstruction step, and it is also suitable for both steady and unsteady flow simulations. We illustrate the accuracy of this scheme by several 1‐D and 2‐D numerical experiments. Copyright © 2005 John Wiley & Sons, Ltd.