全文获取类型
收费全文 | 7223篇 |
免费 | 908篇 |
国内免费 | 542篇 |
专业分类
电工技术 | 195篇 |
技术理论 | 1篇 |
综合类 | 534篇 |
化学工业 | 882篇 |
金属工艺 | 180篇 |
机械仪表 | 169篇 |
建筑科学 | 868篇 |
矿业工程 | 298篇 |
能源动力 | 169篇 |
轻工业 | 713篇 |
水利工程 | 304篇 |
石油天然气 | 2006篇 |
武器工业 | 52篇 |
无线电 | 486篇 |
一般工业技术 | 658篇 |
冶金工业 | 129篇 |
原子能技术 | 147篇 |
自动化技术 | 882篇 |
出版年
2024年 | 45篇 |
2023年 | 180篇 |
2022年 | 306篇 |
2021年 | 365篇 |
2020年 | 333篇 |
2019年 | 301篇 |
2018年 | 236篇 |
2017年 | 246篇 |
2016年 | 333篇 |
2015年 | 287篇 |
2014年 | 478篇 |
2013年 | 560篇 |
2012年 | 534篇 |
2011年 | 507篇 |
2010年 | 369篇 |
2009年 | 327篇 |
2008年 | 348篇 |
2007年 | 337篇 |
2006年 | 382篇 |
2005年 | 320篇 |
2004年 | 322篇 |
2003年 | 269篇 |
2002年 | 196篇 |
2001年 | 178篇 |
2000年 | 175篇 |
1999年 | 130篇 |
1998年 | 97篇 |
1997年 | 112篇 |
1996年 | 78篇 |
1995年 | 49篇 |
1994年 | 54篇 |
1993年 | 50篇 |
1992年 | 45篇 |
1991年 | 23篇 |
1990年 | 24篇 |
1989年 | 24篇 |
1988年 | 5篇 |
1987年 | 6篇 |
1986年 | 5篇 |
1985年 | 7篇 |
1984年 | 9篇 |
1983年 | 1篇 |
1982年 | 2篇 |
1981年 | 3篇 |
1980年 | 5篇 |
1979年 | 3篇 |
1977年 | 4篇 |
1965年 | 1篇 |
1960年 | 1篇 |
1959年 | 1篇 |
排序方式: 共有8673条查询结果,搜索用时 15 毫秒
71.
72.
73.
基于波动方程的聚焦点控制照明叠前深度偏移技术借助于差分计算,把速度、密度等介质参数的影响体现在差分计算的矩阵方程中,能够自动适应速度场的任意变化,快速傅里叶变换的使用也加速了波场延拓的计算速度。因此此法兼具有限差分偏移方法和傅里叶偏移方法的优点,既可适应速度场的剧烈变化,又可保证对陡倾地层的成像效果,是目前针对复杂构造最有效的成像方法之一。对于单个聚焦点及其周围的成像步骤为:①采用矩形网格情况下绕射走时的有限差分计算方法生成合成算子;②应用合成算子来合成面炮震源和面波记录;③对合成的面炮震源和面波记录做傅里叶有限差分法波动方程叠前深度偏移,得到该聚焦点及其附近区域的成像结果。按照上述成像步骤,将震源波场和炮集记录依据相应的外推公式进行延拓,最终应用成像条件求取成像值。在地质目标处选取多个聚焦点,可以得到面向目标的控制照明偏移成像,在多个层位上选取多个聚焦点进行控制照明叠前深度偏移,可以得到整块区域的成像。通过对Marmousi模型的试算,取得了较好的效果。 相似文献
74.
75.
Compressive sensing(CS) techniques offer a framework for the detection and allocation of sparse signal with a reduced number of measurements.This paper proposes a novel SAR range compression,namely compressive sensing with chirp scaling(CS-CS),achieving the same range resolution as conventional SAR approach,while using fewer range samplings.In order to realize accurate range cell migration correction(RCMC),chirp scaling principle is used to construct reference matrix for compressive sensing recovery.Additionally,error diagrams are designed for measurement of the performance of CS-CS,and some experiments of using real data are performed to deal with the errors caused by three conditions:SNR,sparsity and sampling. 相似文献
76.
77.
The voltage-gated proton channel, Hv1, also termed VSOP, was discovered in 2006. It has long been suggested that proton transport through voltage-gated proton channels regulate reactive oxygen species (ROS) production in phagocytes by counteracting the charge imbalance caused by the activation of NADPH oxidase. Discovery of Hv1/VSOP not only confirmed this process in phagocytes, but also led to the elucidation of novel functions in phagocytes. The compensation of charge by Hv1/VSOP sustains ROS production and is also crucial for promoting Ca2+ influx at the plasma membrane. In addition, proton extrusion into neutrophil phagosomes by Hv1/VSOP is necessary to maintain neutral phagosomal pH for the effective killing of bacteria. Contrary to the function of Hv1/VSOP as a positive regulator for ROS generation, it has been revealed that Hv1/VSOP also acts to inhibit ROS production in neutrophils. Hv1/VSOP inhibits hypochlorous acid production by regulating degranulation, leading to reduced inflammation upon fungal infection, and suppresses the activation of extracellular signal-regulated kinase (ERK) signaling by inhibiting ROS production. Thus, Hv1/VSOP is a two-way player regulating ROS production. Here, we review the functions of Hv1/VSOP in neutrophils and discuss future perspectives. 相似文献
78.
Shuzhen Liu Guoyan An Qing Cao Tong Li Xinyu Jia Lei Lei 《International journal of molecular sciences》2021,22(11)
Increasing numbers of miRNAs have been observed as oncogenes or tumor suppressors in colorectal cancer (CRC). It was recently reported that hsa-miR-106b-5p (miR-106b) promoted CRC cell migration and invasion. However, there were also studies showing contradictory results. Therefore, in the present study, we further explore the role of miR-106b and its downstream networks in the carcinogenesis of CRC. We observed that the expression of miR-106b is significantly increased in Pan-Cancer and CRC tissues compared with normal tissues from The Cancer Genome Atlas (TCGA) database. Furthermore, we used Transwell, Cell Counting Kit-8, and colony formation assays to clarify that miR-106b promotes the migratory, invasive, and proliferative abilities of CRC cells. For the first time, we systematically screened the target mRNAs and lncRNAs of miR-106b using TCGA database and the bioinformatics algorithms. Dual-luciferase reporter assay confirmed that NR2F2-AS1 and PLEKHO2 are the direct targets of miR-106b. Furthermore, NR2F2-AS1 acts as a competing endogenous RNA (ceRNA) to regulate PLEKHO2 expression by sponging miR-106b. The results of Gene set enrichment analysis (GSEA) and Western blot indicated that they play important roles in CRC progression by regulating MAPK pathway. Thus, miR-106b/NR2F2-AS1/PLEKHO2/MAPK signaling axis may suggest the potential usage in CRC treatment. 相似文献
79.
Alexandra Calle Víctor Toribio María Yez-M Miguel ngel Ramírez 《International journal of molecular sciences》2021,22(11)
Embryonic implantation is a key step in the establishment of pregnancy. In the present work, we have carried out an in-depth proteomic analysis of the secretome (extracellular vesicles and soluble proteins) of two bovine blastocysts embryonic trophectoderm primary cultures (BBT), confirming different epithelial–mesenchymal transition stages in these cells. BBT-secretomes contain early pregnancy-related proteins and angiogenic proteins both as cargo in EVs and the soluble fraction. We have demonstrated the functional transfer of protein-containing secretome between embryonic trophectoderm and maternal MSC in vitro using two BBT primary cultures eight endometrial MSC (eMSC) and five peripheral blood MSC (pbMSC) lines. We observed that eMSC and pbMSC chemotax to both the soluble fraction and EVs of the BBT secretome. In addition, in a complementary direction, we found that the pattern of expression of implantation proteins in BBT-EVs changes depending on: (i) their epithelial–mesenchymal phenotype; (ii) as a result of the uptake of eMSC- or pbMSC-EV previously stimulated or not with embryonic signals (IFN-τ); (iii) because of the stimulation with the endometrial cytokines present in the uterine fluid in the peri-implantation period. 相似文献
80.
摘要:对链箅机回转窑工艺中各段球团样品进行实验分析,研究了氯元素和硫元素在链箅机回转窑工艺中的迁移规律,明晰了烟气中HCl的生成机制。结果表明,球团原料中的氯元素主要是以NaCl的形式存在,氯元素有一部分在链箅机抽风干燥段会转变成HCl气体并进入烟气,一部分在链箅机预热Ⅱ段之后以NaCl的形式汽化进入烟气,剩余的氯元素仍以NaCl的形式存在于成品球团矿中。烟气中的HCl气体是在抽风干燥段,由富含SO2的烟气与含水球团料层中的NaCl发生反应生成的,烟气中SO2转变成Na2SO4重新固定于料层中。在预热Ⅰ段和预热Ⅱ段,烟气中的SO2与原料中碳酸钙分解生成的游离CaO反应生成CaSO4,也会重新固定烟气中的SO2。 相似文献