Who avoids location-based advertising and why? Investigating the relationship between user perceptions and advertising avoidance

This study investigates how perceptual factors are associated with mobile consumers’ avoidance of location-based mobile advertising (LBA), and whether the relationships between the perceptual factors and LBA avoidance are influenced by consumers’ mobile device usage levels. The results of a national web survey with 605 Singaporean mobile consumers show that those who find LBA impedes goals, requires sacrifice, and lacks utility are more likely to avoid it. When examining the differences of heavy, medium, and light mobile device users, the analyses reveal that the effects of perceived utility and entertainment on LBA avoidance are greater for medium and heavy users than for light users. Theoretical and practical implications of our findings are discussed, as are the limitations and suggestions for future research.     

广州国际体育演艺中心比分、大屏幕显示及升降系统

本文简要介绍了比分、大屏幕显示及升降系统在广州国际体育演艺中心的设计特色。     

优化工艺 提高直硝高压釜使用寿命

从工艺上分析了影响直硝高压釜反应效率及使用寿命的因素，并提出了具体的工艺优化措施。     

Nanosponge-based pediatric-controlled release dry suspension of Gabapentin for reconstitution

Abstract

Context: Gabapentin was selected to formulate oral controlled release dry suspension because of short biological half life of 5–7?h and low bioavailability (60%). Gabapentin is a bitter drug so an attempt was made to mask its taste.

Objective: To formulate and evaluate controlled release dry suspension for reconstitution to increase the bioavailability and to control bitter taste of drug.

Materials and methods: Cyclodextrin based nanosponges were synthesized by previously reported melt method. The nanosponge–drug complexes were characterized by FTIR, DSC and PXRD as well as evaluated for taste and saturation solubility. The complexes were coated on Espheres by a suspension layering technique followed by coating with ethyl cellulose and Eudragit RS-100. A dry powder suspension for reconstitution of the microspheres was formulated and evaluated for taste, redispersibility, in vitro dissolution, sedimentation volume, leaching and pharmacokinetics.

Results and discussion: The complexes showed partial entrapment of drug nanocavities. Significant decrease in solubility (25%) was observed in the complexes than pure drug in different media. The microspheres of nanosponge complexes showed desired controlled release profile for 12?h. Insignificant drug leaching was observed in reconstituted suspension during storage for 7 days at 45?°C/75% RH. Nanosponges effectively masked the taste of Gabapentin and the coating polymers provided controlled release of the drug and enhanced taste masking. The results of in vivo studies showed increase in bioavailability of controlled release suspension by 24.09% as compared to pure drug.

Conclusion: The dry powder suspension loaded with microspheres of nanosponges complexes can be proposed as a suitable controlled release drug delivery for Gabapentin.     

黄河流域：商丘城市空间营造

该文是个案研究系列之泛黄河流域商丘城市空间营造研究,对商丘城市族群的更替叠累及城市空间营造进行了分析研究.     

挖掘式装载机运输槽改制

对挖掘式装载机的构件、作用及工作原理进行了简要介绍,并通过计算分析,着重对运输槽及运输槽刮板的改制方法进行了探讨,以提高挖掘式装载机的工作效率,满足其工况需求。     

谈工程量清单计价下的合同管理与结算的关系

对清单计价规范实施后,工程量计价模式下的工程合同管理与结算的关系进行了探讨,总结了加强工程量清单结算管理的措施和工程价款结算争议处理方法,最后指出加强施工合同的管理,对提高工程结算的效率和质量具有重要作用。     

基于样本的流行歌曲关键段分割方法

流行歌曲的关键段为歌曲中最能打动人、给人印象最深刻的一个完整片段.将它分割出来可用于音乐试听和基于内容的音乐分类、检索、管理.通过对人工截取的样本进行分析,本文提出了一种流行歌曲关键段自动分割方法.实验结果表明,此方法可以比较准确和有效地分割出流行歌曲中的关键段.     

基于混合FE-SEA法的镁质油底壳隔声数值优化

用混合FE-SEA法分析相同厚度的钢、铝合金和镁合金三种材质油底壳的隔声量,综合考虑轻量化和降噪的要求,提出降噪效率的概念,将其作为评价指标,结果显示镁质油底壳的综合性能最为优越。为了更进一步改善镁质油底壳的隔声效果,对隔声低谷处的模态贡献量进行分析,找出隔声低谷的关键参与模态。通过调取该频率处的速度振型,识别出油底壳上严重振动区域,在此区域内表面添加加强筋,有效地抑制了振动,同时低谷处的隔声也得到明显的改善。     

湿法磷酸生产中过滤冲盘系统运行评价

结合转台式过滤机在湿法磷酸生产中的应用,从工艺设计、设备运转和工艺运行等3个方面比较分析了过滤冲盘系统存在的问题并提出相应的改进措施,同时评价其运行效果。实践证明：转台式过滤机冲盘系统运行平稳、冲盘效果良好,可实现高产低耗的目标,且滤布使用寿命比翻盘式过滤机长2～3倍。