舰载雷达探测误差传递与灵敏度分析

在舰艇及编队指控系统中,来自不同平台的传感器探测系统偏差失配是影响态势一致性的关键因素。本文采用理论建模和数字仿真相结合的方法,对舰载雷达探测和处理涉及各环节的偏差进行分析,建立了雷达测量、坐标转换、平台定姿定位和基线转换等各环节偏差影响模型和舰载雷达探测的等效偏差模型。理论分析和计算机仿真结果表明,雷达方位测量、平台艏向和甲板艏向形变引起的偏差均可以直接迭加到方位上,合并为方位偏差;同时,在目标俯仰角小于10°的情况下,基本上可以忽略甲板形变、平台姿态偏差对目标方位测量的影响。     

基于灵敏度分析的FPGM剪枝算法研究

针对等比例剪枝导致的重要卷积层剪枝过度、残留大量冗余参数以及精度损失较大的问题,在FPGM剪枝策略基础上融入灵敏度分析进行网络剪枝。算法采用精度反馈来分析每一层卷积层的重要性,控制单层剪枝比例分析每一层不同剪枝比例对精度损失的影响,获取各个卷积层的灵敏度;结合FPGM策略分析卷积层内卷积核的重要程度按灵敏度的剪枝比例剪掉不重要的卷积核,达到对神经网络进行有效剪枝的目的。实验结果表明,所提方法在MobileNet-v1和ResNet50上剪枝率为50%的情况下,精确度仅下降1.56%和0.11%;所提方法在精度损失一致下,ResNet50上具有更高剪枝率和更低计算量。     

Influence of base resistance on extracting thermal resistance for SiGe HBTs

In this article, the influence of base resistance on extracting thermal resistance for SiGe heterojunction bipolar transistors is studied and an improved approach for determining the junction temperature and thermal resistance is presented. The proposed method for extracting thermal resistance is based on the temperature sensitivity of the base–emitter (B–E) voltage when the device is biased with a fixed emitter current density. This approach not only takes into account the self‐heating during the different ambient temperature measurement but also revises the empirical equation of B–E voltage due to the influence of base resistance during the power dissipation increment measurement. Results are obtained for devices with different emitter lengths and fingers. Compared with the conventional method, the thermal resistance is about up to 15% improvement for the device with 0.3 × 1.9 μm² emitter area and 13.8% for the device with 0.3 × 13.9 μm² emitter area. The accurate thermal resistance implemented in HICUM model has resulted in better fit for transistor output characteristics. © 2012 Wiley Periodicals, Inc. Int J RF and Microwave CAE, 2012.     

线性系统的H2/H-故障检测优化方法设计

针对一类具有未知扰动的线性系统的故障检测(FD)问题,通过对系统进行重构,设计出了系统的H2/H-优化FD观测器。利用构造的Lyapunov函数和线性矩阵不等式,证明并给出了FD观测器有解的充分条件和优化设计方法。所设计的观测器使系统具有渐近稳定性,抑制干扰能力强,满足所给的范数指标。仿真结果验证了所设计方法的有效性。     

Integration of Data from Liquid–Liquid Phase Separation Databases Highlights Concentration and Dosage Sensitivity of LLPS Drivers

Liquid–liquid phase separation (LLPS) is a molecular process that leads to the formation of membraneless organelles, representing functionally specialized liquid-like cellular condensates formed by proteins and nucleic acids. Integrating the data on LLPS-associated proteins from dedicated databases revealed only modest agreement between them and yielded a high-confidence dataset of 89 human LLPS drivers. Analysis of the supporting evidence for our dataset uncovered a systematic and potentially concerning difference between protein concentrations used in a good fraction of the in vitro LLPS experiments, a key parameter that governs the phase behavior, and the proteomics-derived cellular abundance levels of the corresponding proteins. Closer scrutiny of the underlying experimental data enabled us to offer a sound rationale for this systematic difference, which draws on our current understanding of the cellular organization of the proteome and the LLPS process. In support of this rationale, we find that genes coding for our human LLPS drivers tend to be dosage-sensitive, suggesting that their cellular availability is tightly regulated to preserve their functional role in direct or indirect relation to condensate formation. Our analysis offers guideposts for increasing agreement between in vitro and in vivo studies, probing the roles of proteins in LLPS.     

基于剪切带扩展法的海底斜坡稳定性分析

简介剪切带扩展法（SBP）的原理及其在海底滑坡稳定性分析的应用;以舟山六横岛典型海底斜坡为分析案例,开展基于高斯函数的SBP和极限平衡法（LEM）斜坡稳定性对比分析研究;进行SBP输入参数对剪切带扩展系数R的敏感度分析. 研究结果显示,对于斜坡剪切带破坏长度,当剪切带扩展系数R不大于1时,LEM与SBP得到的滑坡滑裂面区域一致,当R大于1时,SBP计算得到的最终滑动区域比LEM计算得到的区域大;在斜坡发生滑动破坏区域SBP比LEM计算得到的安全系数低;地震影响因素和土体特征位移对R的影响较大.     

6UPS并联机构杆长误差标定及其对动平台运动的影响分析

分析了不同误差对并联机构的影响,尤其是杆长误差对动平台姿态误差的影响.建立了采用并联机构运动学反解模型的矢量法误差求解模型;针对6UPS并联刀具机构的结构特点,使用支链分析方法,对由杆长误差引起的动平台误差变化趋势及变化的敏感性方向进行了分析.使用激光干涉仪完成了误差测量实验,使用多组姿态数据的不同组合进行误差计算,获得了优化的杆长误差数据.完成了杆长误差对动平台误差变化影响的数值分析与矢量合成两种方法的验证.     

重力坝弹性参数反演的灵敏度分析及一种新的反演算法

依据结构灵敏度分析理论,采用基于有限单元法的解析灵敏度分析方法,对影响重力坝材料参数反演质量的位移观测点位置进行了研究,得到了坝顶位移最适合于反演大坝弹性模量的结论。同时引入一种新的群集智能优化方法—人工鱼群算法（AFSA）,根据大坝坝顶的增量位移进行混凝土大坝和坝基岩石材料参数的反演。算例分析表明：AFSA能够稳定快速地收敛到所求参数的全局最优值;同时加入不同水平的噪音对该算法的数值稳定性进行了研究,结果表明算法稳定性良好。     

3D Prussian blue/Pt decorated carbon nanofibers based screen-printed microchips for the ultrasensitive hydroquinone biosensing

Nowadays,water pollution has become more serious,greatly affecting human life and healthy.Electrochemical biosensor,a novel and rapid detection technique,plays an important role in the real-time and trace detection of water pollutants.However,the stability and sensitivity of electrochemical biosensors remain a great challenge for practical detections in real samples to the strong interferences derived from complex components and coagulation effects.In this work,we reported a novel three-dimensional architecture of Prussian blue nanoparticles (PBNPs)/ Pt nanoparticles (PtNPs) composite film,using 3D interweaved carbon nanofibers as a supporting matrix,for the construction of screen-printed microchips-based biosensor.PtNPs with diameters of～2.5 nm was highly dispersed on the carbon nanofibers (CNFs) to build a 3D skeleton nanostructure through a solvothermal reduction.Subsequently,uniform PBNPs were in-situ self-assembled on this skeleton to construct a 3D architecture of PB/Pt-CNF composite film.Due to the synergistic effects derived from this special feature,the as-prepared hydro-quinone (HQ) biosensor chips can synchronously promote both surface area and conductivity to greatly enhance the electrocatalysis from enzymatic reaction.This biosensor has exhibited a high sensitivity of 220.28 μA·L·mmol-1·cm-2 with an ultrawide linear range from 2.5μmol·L-1 to 1.45 mmol·L-1 at a low potential of 0.15 V,as well as the satisfactory reproducibility and usage stability.Besides,its accuracy was also verified in the assays of real water samples.It is highly expected that the 3D PB/Pt-CNF based screen-printed microchips will have wide applications in dynamic monitoring and early warning of ana-lytes in the various practical fields.     

Recent Update on the Molecular Mechanisms of Gonadal Steroids Action in Adipose Tissue

The gonadal steroids, including androgens, estrogens and progestogens, are involved in the control of body fat distribution in humans. Nevertheless, not only the size and localization of the fat depots depend on the sex steroids levels, but they can also highly affect the functioning of adipose tissue. Namely, the gonadocorticoids can directly influence insulin signaling, lipid metabolism, fatty acid uptake and adipokine production. They may also alter energy balance and glucose homeostasis in adipocytes in an indirect way, e.g., by changing the expression level of aquaglyceroporins. This work presents the recent advances in understanding the molecular mechanism of how the gonadal steroids influence the functioning of adipose tissue leading to a set of detrimental metabolic consequences. Special attention is given here to highlighting the sexual dimorphism of adipocyte functioning in terms of health and disease. Particularly, we discuss the molecular background of metabolic disturbances occurring in consequence of hormonal imbalance which is characteristic of some common endocrinopathies such as the polycystic ovary syndrome. From this perspective, we highlight the potential drug targets and the active substances which can be used in personalized sex-specific management of metabolic diseases, in accord with the patient’s hormonal status.