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排序方式: 共有4148条查询结果,搜索用时 31 毫秒
31.
飞机交流发电机是飞机关键部件之一,监测其健康状况具有重要意义。通过设计实验数据获取平台采集交流发电机在转速上升(从6000转/分到8500转/分)、平稳运行(7500转/分)及转速下降(8500转/分到6000转/分)三个阶段的振动信号,利用符号序列Shannon熵的计算方法以及符号化方法设定合适参数对振动信号进行了处理,得出了交流发电机在三个阶段的振动信号的Shannon熵;通过初步的分析表明,交流发电机在正常状态下三个阶段的Shannon熵都比较有规律的在一定范围内变化,一旦发生振动异常将会引起Shannon熵突变;经过分析讨论,Shannon熵的突变与否是可以用来反映交流发电机在机械方面是否存在故障隐患的。 相似文献
32.
Xiuming Huang 《Machine Translation》1988,3(2):101-120
This paper concerns the resolution of lexical ambiguity in a machine translation environment. We describe the integration of principles of selection restrictions. Preference Semantics, and intelligent relaxation of constraints in handling lexical ambiguity. The approach differs from many previous MT systems in that it is more powerful than brute force systems, while more realistic than systems that assume a large degree of coded encyclopedia information for full understanding. 相似文献
33.
Autism spectrum disorder (ASD) is a heritable neurodevelopmental condition associated with impairments in social interaction, communication and repetitive behaviors. While the underlying disease mechanisms remain to be fully elucidated, dysfunction of neuronal plasticity and local translation control have emerged as key points of interest. Translation of mRNAs for critical synaptic proteins are negatively regulated by Fragile X mental retardation protein (FMRP), which is lost in the most common single-gene disorder associated with ASD. Numerous studies have shown that mRNA transport, RNA metabolism, and translation of synaptic proteins are important for neuronal health, synaptic plasticity, and learning and memory. Accordingly, dysfunction of these mechanisms may contribute to the abnormal brain function observed in individuals with autism spectrum disorder (ASD). In this review, we summarize recent studies about local translation and mRNA processing of synaptic proteins and discuss how perturbations of these processes may be related to the pathophysiology of ASD. 相似文献
34.
Sevinj Sultanli Soni Ghumnani Richa Ashma Katharina F. Kubatzky 《International journal of molecular sciences》2021,22(5)
Plumbagin is a plant-derived naphthoquinone that is widely used in traditional Asian medicine due to its anti-inflammatory and anti-microbial properties. Additionally, plumbagin is cytotoxic for cancer cells due to its ability to trigger reactive oxygen species (ROS) formation and subsequent apoptosis. Since it was reported that plumbagin may inhibit the differentiation of bone resorbing osteoclasts in cancer-related models, we wanted to elucidate whether plumbagin interferes with cytokine-induced osteoclastogenesis. Using C57BL/6 mice, we unexpectedly found that plumbagin treatment enhanced osteoclast formation and that this effect was most pronounced when cells were pre-treated for 24 h with plumbagin before subsequent M-CSF/RANKL stimulation. Plumbagin caused a fast induction of NFATc1 signalling and mTOR-dependent activation of p70S6 kinase which resulted in the initiation of protein translation. In line with this finding, we observed an increase in RANK surface expression after Plumbagin stimulation that enhanced the responsiveness for subsequent RANKL treatment. However, in Balb/c mice and Balb/c-derived RAW264.7 macrophages, these findings could not be corroborated and osteoclastogenesis was inhibited. Our results suggest that the effects of plumbagin depend on the model system used and can therefore either trigger or inhibit osteoclast formation. 相似文献
35.
To improve the accuracy of cross-modal pedestrian re-identification,a reciprocal bi-directional generative adversarial network-based method is proposed.First,we build two generative adversarial networks to generate cross-modal heterogeneous images.Second,an associated loss is designed to pull close the distribution of features in latent space during the image translation between visible and infrared images so as to help the networks generate fake heterogeneous images that have high similarity with the real images.Finally,by concatenating the original and generated heterogeneous pedestrian images into the discriminative feature extraction network,images from different modalities can be unified into a common modality,thus suppressing the cross-modal gap.Representation learning and metric learning are utilized to achieve more discriminative pedestrian features.Comparative experiments are conducted on SYSU-MM01 and RegDB datasets to analyze the accuracy with different loss functions.Compared with other state-of-the-art cross-modal pedestrian re-identification methods,the proposed method achieves a higher accuracy and stronger robustness. 相似文献
36.
浅析科技英语中词义的汉译 总被引:1,自引:0,他引:1
通过实例阐述了在进行科技英语的汉译时,只有根据原文的专业、行业、技术内容、词的本义和可能的引伸义,结合词的上下文语境,才能准确、恰当地确定英语词义的汉译。文章指出明白通畅、浅显易懂、准确的词义是科技英语汉译成功的基础。 相似文献
37.
Pavel A. Sakharov Egor A. Smolin Dmitry N. Lyabin Sultan C. Agalarov 《International journal of molecular sciences》2021,22(7)
The methylation of adenosine in the N6 position (m6A) is a widely used modification of eukaryotic mRNAs. Its importance for the regulation of mRNA translation was put forward recently, essentially due to the ability of methylated mRNA to be translated in conditions of inhibited cap-dependent translation initiation, e.g., under stress. However, the peculiarities of translation initiation on m6A-modified mRNAs are not fully known. In this study, we used toeprinting and translation in a cell-free system to confirm that m6A-modified mRNAs can be translated in conditions of suppressed cap-dependent translation. We show for the first time that m6A-modified mRNAs display not only decreased elongation, but also a lower efficiency of translation initiation. Additionally, we report relative resistance of m6A-mRNA translation initiation in the absence of ATP and inhibited eIF4A activity. Our novel findings indicate that the scanning of m6A-modified leader sequences is performed by a noncanonical mechanism. 相似文献
38.
39.
Abstract. A symbolic method which can be used to obtain the asymptotic bias and variance coefficients to order O(1/n) for estimators in stationary time series is discussed. Using this method, the large‐sample bias of the Burg estimator in the AR(p) for p = 1, 2, 3 is shown to be equal to that of the least squares estimators in both the known and unknown mean cases. Previous researchers have only been able to obtain simulation results for the Burg estimator's bias because this problem is too intractable without using computer algebra. The asymptotic bias coefficient to O(1/n) of Yule–Walker as well as least squares estimates is also derived in AR(3) models. Our asymptotic results show that for the AR(3), just as in the AR(2), the Yule–Walker estimates have a large bias when the parameters are near the nonstationary boundary. The least squares and Burg estimates are much better in this situation. Simulation results confirm our findings. 相似文献
40.
带未知干扰的模块化航天器系统相对轨道的队形控制 总被引:1,自引:0,他引:1
基于多智能体系统一致性理论,在有向拓扑结构中对模块化航天器相对轨道的队形控制问题进行研究.考虑与状态相关的未知外部干扰,在存在模块质量不确定性的情形下,基于自适应增益技术,设计仅依赖模块自身及其邻近模块信息的分布式控制算法,并通过Lyapunov稳定性方法证明闭环系统是渐近稳定的.最后在Matlab/Simulink中对6个模块组成的模块化航天器系统的队形进行仿真分析,仿真结果表明所设计的控制律是有效且可行的. 相似文献