固态功率控制器感性负载下的续流特性分析

本文结合我国空间站用固态功率控制器保护特性,对其在不同关断模式下的续流特性进行了理论分析,并通过建模仿真给出了不同感性负载下关断电流对功率回路MOSFET、二极管关键半导体器件的电、热应力影响,最后给出了固态功率控制器感性负载下的使用注意事项,对固态功率控制器安全性设计及使用具有一定的参考意义。     

Recent progress in continuous and semi-continuous processing of solid oral dosage forms: a review

Context: Continuous processing is an innovative production concept well known and successfully used in other industries for many years. The modern pharmaceutical industry is facing the challenge of transition from a traditional manufacturing approach based on batch-wise production to a continuous manufacturing model.

Objective: The aim of this article is to present technological progress in manufacturing based on continuous and semi-continuous processing of the solid oral dosage forms.

Methods: Single unit processes possessing an alternative processing pathway to batch-wise technology or, with some modification, an altered approach that may run continuously, and are thus able to seamlessly switch to continuous manufacturing are briefly presented. Furthermore, the concept of semi-continuous processing is discussed. Subsequently, more sophisticated production systems created by coupling single unit processes and comprising all the steps of production, from powder to final dosage form, were reviewed. Finally, attempts of end-to-end production approach, meaning the linking of continuous synthesis of API from intermediates with the production of final dosage form, are described.

Results: There are a growing number of scientific articles showing an increasing interest in changing the approach to the production of pharmaceuticals in recent years. Numerous scientific publications are a source of information on the progress of knowledge and achievements of continuous processing. These works often deal with issues of how to modify or replace the unit processes in order to enable seamlessly switching them into continuous processing. A growing number of research papers concentrate on integrated continuous manufacturing lines in which the production concept of “from powder to tablet” is realized. Four main domains are under investigation: influence of process parameters on intermediates or final dosage forms properties, implementation of process analytical tools, control-managing system responsible for keeping continuous materials flow through the whole manufacturing process and the development of new computational methods to assess or simulate these new manufacturing techniques. The attempt to connect the primary and secondary production steps proves that development of continuously operating lines is possible.

Conclusion: A mind-set change is needed to be able to face, and fully assess, the advantages and disadvantages of switching from batch to continuous mode production.     

Continuous wavelet analysis for the detection of green attack damage due to mountain pine beetle infestation

Mountain pine beetle (Dendroctonus ponderosae Hopkins) is the most destructive insect infesting mature pine forests in North America and has devastated millions of hectares of forest in western Canada. Past studies have demonstrated the use of multispectral imagery for remote identification and mapping of visible or red attack damage in forests. This study aims to detect pre-visual or green attack damage in lodgepole pine needles by means of hyperspectral measurements, particularly via continuous wavelet analysis. Field measurements of lodgepole pine stands were conducted at two sites located northwest of Edmonton, Alberta, Canada. In June and August of 2007, reflectance spectra (350-2500 nm) were collected for 16 pairs of trees. Each of the 16 tree pairs included one control tree (healthy), and one stressed tree (girdled to simulate the effects of beetle infestation). In addition, during the period of June through October 2008, spectra were collected from 15 pairs of control- and beetle-infested trees. Spectra derived from these 31 tree pairs were subjected to a continuous wavelet transform, generating a scalogram that compiles the wavelet power as a function of wavelength location and scale of decomposition. Linear relationships were then explored between the wavelet scalograms and chemical properties or class labels (control and non-control) of the sample populations in order to isolate the most useful distinguishing spectral features that related to infested or girdled trees vs. control trees.A deficit in water content is observed in infested trees while an additional deficit in chlorophyll content is seen for girdled trees. The measurable water deficit of infested and girdled tree samples was detectable from the wavelet analysis of the reflectance spectra providing a novel method for the detection of green attack. The spectral features distinguishing control and infested trees are predominantly located between 950 and 1390 nm from scales 1 to 8. Of those, five features between 1318 to 1322 nm at scale 7 are consistently found in the July and August 2008 datasets. These features are located at longer wavelengths than those investigated in previous studies (below 1100 nm) and provide new insights into the potential remote detection of green attack. Spectral features that distinguish control and girdled trees were mostly observed between 1550 and 2370 nm from scales 1 to 5. The differing response of girdled and infested trees appears to indicate that the girdling process does not provide a perfect simulation of the effects caused by beetle infestation.It remains to be determined if the location of the 1318-1322 nm features, near the edge of a strong atmospheric water absorption band, will be sufficiently separable for use in airborne detection of green attack. A plot comparing needle water content and wavelet power at 1320 nm reveals considerable overlap between data derived from both infested and control samples, though the groups are statistically separable. This obstacle may preclude a high accuracy separation of healthy and infected single individuals, but establishing threshold identification levels may provide an economical, efficient and expeditious method for discriminating between healthy and infested tree populations.     

道路网络中的连续最近邻查询

为了减少连续最近邻查询中计算K个最近邻的次数和减小算法需要的存储空间,提出一种道路网络中求连续最近邻的方法。给出分点的计算方法及连续最近邻查询算法,对算法的正确性、可终止性进行证明,并分析算法复杂度。与相关算法进行实验比较,得出该算法更适合于对象频繁发生变化的实际网络。     

Finding an Euclidean anti--centrum location of a set of points

An obnoxious facility is to be located inside a polygonal region of the plane, maximizing the sum of the k smallest weighted Euclidean distances to n given points, each protected by some polygonal forbidden region. For the unweighted case and k fixed an O(n²logn) time algorithm is presented. For the weighted case a thorough study of the relevant structure of the multiplicatively weighted order-k-Voronoi diagram leads to the design of an O(kn³+n³logn) time algorithm for finding an optimal solution to the anti-t-centrum problem for every t=1,…,k, simultaneously.     

Cancellation of bulging effect on mould level in continuous casting: Experimental validation

During the continuous casting of steel, several disturbances occur and affect all the parts of the caster, including the mould where the molten steel has to be stable for good quality of the final product. Especially at high casting velocities, the bulging generates important level fluctuations which cannot be efficiently rejected by the classical controllers. To address these problems, this paper proposes an architecture combining disturbances estimation and compensation techniques. It operates as an additional module and does not need any change of the main controller currently implemented. The entire structure has been tested successfully through several simulations and by means of intensive water model experiments.     

Maintaining consistent results of continuous queries under diverse window specifications

Continuous queries applied over nonterminating data streams usually specify windows in order to obtain an evolving–yet restricted–set of tuples and thus provide timely and incremental results. Although sliding windows get frequently employed in many user requests, additional types like partitioned or landmark windows are also available in stream processing engines. In this paper, we set out to study the existence of monotonic-related semantics for a rich set of windowing constructs in order to facilitate a more efficient maintenance of their changing contents. After laying out a formal foundation for expressing windowed queries, we investigate update patterns observed in most common window variants as well as their impact on adaptations of typical operators (like windowed join, union or aggregation), thus offering more insight towards design and implementation of stream processing mechanisms. Furthermore, we identify syntactic equivalences in algebraic expressions involving windows, to the potential benefit of query optimizations. Finally, this framework is validated for several windowed operations against streaming datasets with simulations at diverse arrival rates and window specifications, providing concrete evidence of its significance.     

Stochastic differential equations driven by a Wiener process and fractional Brownian motion: Convergence in Besov space with respect to a parameter

A stochastic differential equation involving both a Wiener process and fractional Brownian motion, with nonhomogeneous coefficients and random initial condition, is considered. The coefficients and initial condition depend on a parameter. The assumptions on the coefficients and the initial condition supplying continuous dependence of the solution on a parameter, with respect to the Besov space norm, are established.     

基于FPGA的逻辑分析仪连续触发模块设计

该文介绍一种逻辑分析仪数据捕获模式的设计原理与实现方法。该模式主要用于嵌入式软件的测试分析,它不再采用采样的方式来采集数据,而是利用软件插桩与硬件设置触发字相结合的方法来监视系统总线。当程序运行到插桩点时,硬件将产生触发,此时才会主动地到总线上将相应数据与对应的具体时问捕获回来,从而实现有效数据的精确捕获。此外,在FPGA内部采用双RAM交替读写的方式来暂存数据,在不中断程序运行的情况下,实现有效数据的长时间实时存取与分析,提高嵌入式软件性能分析的范围和质量。采用FPGA作为构成硬件架构的基本功能器件,提高了工作速度,使整个设计具具有集成度高、性能稳定、调试方便等特点。该模块在实际应用中得到了验证,并取得了良好的效果。     

Frequency-domain identification of continuous-time ARMA models from sampled data

The subject of this paper is the direct identification of continuous-time autoregressive moving average (CARMA) models. The topic is viewed from the frequency domain perspective which then turns the reconstruction of the continuous-time power spectral density (CT-PSD) into a key issue. The first part of the paper therefore concerns the approximate estimation of the CT-PSD from uniformly sampled data under the assumption that the model has a certain relative degree. The approach has its point of origin in the frequency domain Whittle likelihood estimator. The discrete- or continuous-time spectral densities are estimated from equidistant samples of the output. For low sampling rates the discrete-time spectral density is modeled directly by its continuous-time spectral density using the Poisson summation formula. In the case of rapid sampling the continuous-time spectral density is estimated directly by modifying its discrete-time counterpart.