创新培训基地给力企业发展

企业培训基地因企业战略而存在,也直接服务于企业HR战略。培训基地不仅是员工进企业的第一道门槛,也是员工持续提高、实现职业规划、服务企业并终身受益的智囊机构。培训基地与企业、与员工一起成长,并先于企业的知识、人才集聚,先于员工职业生涯发展的需要,因此,他要在创新中发展,创新中满足企业与员工发展的需要。创新源于创新思维与创新环境,基于管理研究和科研创新。     

中小企业人力资源外包决策分析

人力资源外包是一个非常复杂的过程,它能给企业带来新的发展机会,但如果盲目地进行外包也可能会导致企业核心能力和竞争优势的丧失。特别是对于还处于不稳定状态的中小企业,是否应该进行人力资源外包,成为中小企业在实施人力资源外包前必须认清和解决的问题。本文通过运用层次分析法,建立了中小企业人力资源外包决策模型,为中小企业进行人力资源外包决策提供了有效的分析方法。     

基于LabVIEW SIT的 PCI板卡驱动开发

LabVIEW SIT(simulation interface toolkit)是由NI公司开发的一套仿真接口工具包,它能够实现LabVIEW和Simulink仿真模型的无缝链接。在提出了一种基于LabVIEW SIT的典型快速控制原型开发架构后,分析了LabVIEW SIT环境下PCI板卡驱动程序的实现方法。以PCI-9111HR多功能数据采集卡为例,介绍了驱动程序开发的方法及编程要点,给出了LabVIEW SIT下驱动程序的基本框架,并提供了部分关键代码。在某导弹舵机半实物仿真系统中的运行结果表明该驱动程序运行稳定、可靠。     

68.5 W连续输出1 060 nm波段半导体激光列阵模块

利用InGaAs/InGaAsP应变量子阱外延层材料制作出高功率半导体激光列阵模块。激光芯片宽1 cm,腔长1200 μm,条宽200 μm,填充密度为50%,前后腔面光学膜分别为单层Al₂O₃和Al₂O₃/5(HfO₂/SiO₂)/HfO₂,室温连续输出功率达到68.5 W,器件光谱中心波长为1 059 nm,光谱宽度(FWHM)为9 nm。     

HR3C在超临界水中的腐蚀性能研究

通过高压釜浸泡实验研究了超级奥氏体不锈钢HR3C在循环的超临界水（SCW）中的均匀腐蚀性能,实验温度分别为550、600、650 ℃,压力为25 MPa,并对实验后试样生成的氧化膜进行了SEM、EDS和XRD分析。实验结果显示,HR3C在SCW环境中的氧化腐蚀速率随着温度的升高而增大,1 500 h后650 ℃ SCW环境下材料的腐蚀增重约为550 ℃时的2倍。材料表面生成的氧化膜主要成分为FeCr₂O₃、Fe₃O₄和Fe₂O₃,内层氧化膜富Cr而外层氧化膜富Fe。     

数字地震仪采集系统中滤波器设计

滤波器是数字地震采集系统中的重要组成部分，文章简要地比较了两种数字滤波器，并给出了适合于地震采集器的滤波器的设计。     

H814-902/不饱和聚酯树脂/淤泥体系收缩研究

在淤泥填充不饱和聚酯树脂的新体系中加入低收缩添加剂H814-902控制固化收缩。通过体积收缩率计算,研究不饱和聚酯树脂/淤泥体系、不饱和聚酯树脂/淤泥/低收缩添加剂体系收缩性能和抗弯强度。研究结果表明:当低收缩添加剂、不饱和聚酯树脂、淤泥之间的质量比为18∶100∶100时,其体系收缩率达到将其用于低收缩片状模塑料的要求;当玻璃纤维的质量分数为30%时,其抗弯强度达到低收缩片状模塑料强度100 MPa的要求。研究中首次尝试采用高分辨魔角旋转核磁共振(HR/MAS-NMR)方法,并结合SEM方法分析不饱和聚酯树脂/淤泥/低收缩添加剂体系抗收缩机理,提出该体系中空穴、两相岛屿状结构以及固化反应中交联度的下降是抑制体系收缩的主要原因。     

PTEN Loss Enhances Error-Prone DSB Processing and Tumor Cell Radiosensitivity by Suppressing RAD51 Expression and Homologous Recombination

PTEN has been implicated in the repair of DNA double-strand breaks (DSBs), particularly through homologous recombination (HR). However, other data fail to demonstrate a direct role of PTEN in DSB repair. Therefore, here, we report experiments designed to further investigate the role of PTEN in DSB repair. We emphasize the consequences of PTEN loss in the engagement of the four DSB repair pathways—classical non-homologous end-joining (c-NHEJ), HR, alternative end-joining (alt-EJ) and single strand annealing (SSA)—and analyze the resulting dynamic changes in their utilization. We quantitate the effect of PTEN knockdown on cell radiosensitivity to killing, as well as checkpoint responses in normal and tumor cell lines. We find that disruption of PTEN sensitizes cells to ionizing radiation (IR). This radiosensitization is associated with a reduction in RAD51 expression that compromises HR and causes a marked increase in SSA engagement, an error-prone DSB repair pathway, while alt-EJ and c-NHEJ remain unchanged after PTEN knockdown. The G₂-checkpoint is partially suppressed after PTEN knockdown, corroborating the associated HR suppression. Notably, PTEN deficiency radiosensitizes cells to PARP inhibitors, Olaparib and BMN673. The results show the crucial role of PTEN in DSB repair and show a molecular link between PTEN and HR through the regulation of RAD51 expression. The expected benefit from combination treatment with Olaparib or BMN673 and IR shows that PTEN status may also be useful for patient stratification in clinical treatment protocols combining IR with PARP inhibitors.     

HR4 Gene Is Induced in the Arabidopsis-Trichoderma atroviride Beneficial Interaction

Plants are constantly exposed to microbes, for this reason they have evolved sophisticated strategies to perceive and identify biotic interactions. Thus, plants have large collections of so-called resistance (R) proteins that recognize specific microbe factors as signals of invasion. One of these proteins is codified by the Arabidopsis thaliana HR4 gene in the Col-0 ecotype that is homologous to RPW8 genes present in the Ms-0 ecotype. In this study, we investigated the expression patterns of the HR4 gene in Arabidopsis seedlings interacting with the beneficial fungus Trichoderma atroviride. We observed the induction of the HR4 gene mainly at 96 hpi when the fungus interaction was established. Furthermore, we found that the HR4 gene was differentially regulated in interactions with the beneficial bacterium Pseudomonas fluorescens and the pathogenic bacterium P. syringae. When hormone treatments were applied to A. thaliana (Col-0), each hormone treatment induced changes in HR4 gene expression. On the other hand, the expression of the RPW8.1 and RPW8.2 genes of Arabidopsis ecotype Ms-0 in interaction with T. atroviride was assessed. Interestingly, these genes are interaction-responsive; in particular, the RPW8.1 gene shows a very high level of expression in the later stages of interaction. These results indicate that HR4 and RPW8 genes could play a role in the establishment of Arabidopsis interactions with beneficial microbes.