PET中环状低聚物的表征及控制方法的研究进展

鉴于环状低聚物的诸多危害,归纳了PET中环状低聚物的表征方法,具体介绍了低聚物的分离方法及其性能的研究方法,重点总结了目前减少环状低聚物含量的一些新的措施和方法,以期为今后的相关研究提供参考,并提出应该建立工业上简便易行的环状低聚物含量检测方法。     

话语角色转换与戏剧人物形象

话语角色转换是一种语用策略,它透漏出交际者的内在意图。通过分析戏剧人物话语角色的转换来剖析人物的内在意图,可以深入人物内心,帮助理解人物形象的塑造。本文以曹禺的戏剧《日出》中的对话为例,验证话语角色转换理论对于戏剧人物形象的解释力。     

腈纶表面接枝蛋白质改性纤维的结构与性能

腈纶经过表面水解、酰氯化和接枝反应等过程在表面接枝上大豆蛋白质,制成了蛋白质接枝改性腈纶。对其进行物理力学性能分析、红外分析和电子显微镜形貌观察表明:改性腈纶在表面接枝蛋白质的效果明显,其表面完全覆盖上了完整致密的蛋白质表面膜层;X射线衍射分析表明,蛋白质接枝改性腈纶的超分子结构与普通腈纶相比并没有发生大的变化,基本保持了原有腈纶的高序态和低序态共存的结构特征。     

Fighting the Huntington’s Disease with a G-Quadruplex-Forming Aptamer Specifically Binding to Mutant Huntingtin Protein: Biophysical Characterization,In Vitro and In Vivo Studies

A set of guanine-rich aptamers able to preferentially recognize full-length huntingtin with an expanded polyglutamine tract has been recently identified, showing high efficacy in modulating the functions of the mutated protein in a variety of cell experiments. We here report a detailed biophysical characterization of the best aptamer in the series, named MS3, proved to adopt a stable, parallel G-quadruplex structure and show high nuclease resistance in serum. Confocal microscopy experiments on HeLa and SH-SY5Y cells, as models of non-neuronal and neuronal cells, respectively, showed a rapid, dose-dependent uptake of fluorescein-labelled MS3, demonstrating its effective internalization, even in the absence of transfecting agents, with no general cytotoxicity. Then, using a well-established Drosophila melanogaster model for Huntington’s disease, which expresses the mutated form of human huntingtin, a significant improvement in the motor neuronal function in flies fed with MS3 was observed, proving the in vivo efficacy of this aptamer.     

The Role of Lattice Matching Techniques in the Characterization of Polymorphic Forms

An inspection of the recent literature reveals that polymorphism is a frequently encountered phenomenon. The recognition of polymorphic forms plays a vital role in the materials sciences because such structures are characterized by different crystal packing and accordingly have different physical properties. In the pharmaceutical industry, recognition of polymorphic forms can be critical for, in certain cases, a polymorphic form of a drug may be an ineffective therapeutic agent due to its unfavorable physical properties. A check of the recent literature has revealed that in some cases new polymorphic forms are not recognized. In other instances, a supposedly new polymeric form is actually the result of an incorrect structure determination. Fortunately, lattice-matching techniques, which have proved invaluable in the identification and characterization of crystal structures, represent a powerful tool for analyzing polymorphic forms. These lattice-matching methods are based on either of two strategies: (a) the reduced cell strategy–the matching of reduced cells of the respective lattices or (b) the matrix strategy–the determination of a matrix or matrices relating the two lattices coupled with an analysis of the matrix elements. Herein, these techniques are applied to three typical cases–(a) the identification of a new polymorphic form, (b) the demonstration that a substance may not be a new polymorphic form due to missed symmetry, and (c) the evaluation of pseudo polymorphism because of a missed lattice. To identify new polymorphic forms and to prevent errors, it is recommended that these lattice matching techniques become an integral part of the editorial review process of crystallography journals.     

抛光用氧化锆固体粉体的表征与制备研究

为筛选合适的氧化锆粉制备抛光液,采用固体紫外光谱、粉末衍射谱、晶体结构拟合、红外光谱、电子探针显微镜等对进口抛光液Zox-N粉体的成分及其品质进行了分析,确定了抛光粉的组成及国产锆粉制备抛光粉的工艺。结果表明,在氧化锆粉中加入0.18%的氧化铁红,混合均匀后在680～720℃煅烧24h,得到的粉体晶型与Zox-N基本一致。     

Characteristics of origin-destination pair traffic in Funet

In this paper we analyze measurements gathered from a 2.5~Gbps link in the Finnish university network (Funet) in 2004. The traffic is broken down into origin-destination (OD) pair components based on source and destination IP address. We study the traffic characteristics of these components, and identify four typical representative OD pairs. For these pairs we investigate the validity of a moving IID Gaussian model. We find that the statistical properties of these OD pairs differ significantly from each other, with only some of them close to Gaussian. The OD pairs are also found to have some cross-correlation between each other, contradicting an often made assumption about OD pair independence. Furthermore, the existence of a mean-variance relation between the OD pairs is studied. We find that there is a relation between mean and variance, but for some periods of time it is rather weak.     

红外准动态图像平台的设计和实现

介绍了一种用于红外焦平面成像仪参数客观测量的红外准静态图像采集和处理平台的设计与实现。该平台可从动态视频流中以任意格式抽取出任意一帧的数据,用CPLD和DSP自动对其进行处理及分析,并把图像数据通过USB2．0高速总线传回PC,进行保存、显示及检验平台处理的结果。该平台再配合外围探测器和其它器件可方便地对红外热像仪各项参数（NETD、MRTD、MTF）进行客观测量。     

邻苯二甲酰亚氨基酞菁锌(ZnPcS2P2)的光谱特性

测定和研究光敏剂的光谱特性,可为确定最佳治疗的光源波长提供直接依据,同时也是荧光诊断中选定检测荧光波长的理论依据．本文研究新型光敏剂邻苯二甲酰亚氨基酞菁锌（ZnPcS2P2）的光谱特性,测出ZnPcS2P2在含10%人血清生理盐水的吸收光谱和荧光发射光谱,并与血卟啉衍生物（HpD）进行比较。实验结果表明：在吸收光谱中ZnPcS2P2的最大吸收峰位于670nm,而HpD的最大的吸收峰在405nm处,所以在光动力学治疗中ZnPcS2P2比HpD效果更好。当用波长为632nm的光源激发时,从荧光发射光谱可知,HpD比ZnPcS2P2获得的荧光激发效率高。因此,HpD在光动力学诊断中有更突出的优点。