大学生学业自我效能与成就动机的关系

采用学业自我效能问卷和成就动机量表，分层随机选取武汉地区部分高校385名大学生为对象进行研究．结果表明，大学生学习能力自我效能与发展能力自我效能呈正相关，并分别与追求成功的动机呈正相关，与避免失败的动机呈负相关．学习能力自我效能和发展能力自我效能均对追求成功的动机、避免失败的动机和合成成就动机具有显著的贡献．     

努力提高学生的词汇运用能力

学生词汇运用能力的欠缺是英语教学面临的一个亟待解决的问题。通过对这一问题的分析，提出对英语词汇教学应该有新的认识，并结合教学实际探讨词汇教学改革的新路子，以提声学生的词汇运用能力。     

Study on the judgment model of dyeing and weaving corporation＇s core competence

On the basis of the dyeing and weaving corporations＇ characters, this paper put forward the dimensionality and index system to analyze the core competence. This paper divided the core competence into three layers and gave out the Dimensional-Hierarchical structure of core competence through combining the analysis dimensionalities with the competence layers. The model was described to evaluate, analyze and judge the dyeing and weaving corporation＇ s competence.     

实践性课程的设置与英语专业高年级听说课程的整合

综合实践活动是由学生自主实践和探索，将所这语言知识进行综合运用的全新课程。在教学中突出学生的主体作用和教师的指导作用。在语言教学中体现在学生能够将所学的语言知识和技能运用到文化交际，社会交际和社会实践中。介绍了综合实践性课程在英语专业听说教学中的设计、实施、评价和效果。     

The Reliability and Predictive Ability of a Biomarker of Oxidative DNA Damage on Functional Outcomes after Stroke Rehabilitation

We evaluated the reliability of 8-hydroxy-2′-deoxyguanosine (8-OHdG), and determined its ability to predict functional outcomes in stroke survivors. The rehabilitation effect on 8-OHdG and functional outcomes were also assessed. Sixty-one stroke patients received a 4-week rehabilitation. Urinary 8-OHdG levels were determined by liquid chromatography–tandem mass spectrometry. The test-retest reliability of 8-OHdG was good (interclass correlation coefficient = 0.76). Upper-limb motor function and muscle power determined by the Fugl-Meyer Assessment (FMA) and Medical Research Council (MRC) scales before rehabilitation showed significant negative correlation with 8-OHdG (r = −0.38, r = −0.30; p < 0.05). After rehabilitation, we found a fair and significant correlation between 8-OHdG and FMA (r = −0.34) and 8-OHdG and pain (r = 0.26, p < 0.05). Baseline 8-OHdG was significantly correlated with post-treatment FMA, MRC, and pain scores (r = −0.34, −0.31, and 0.25; p < 0.05), indicating its ability to predict functional outcomes. 8-OHdG levels were significantly decreased, and functional outcomes were improved after rehabilitation. The exploratory study findings conclude that 8-OHdG is a reliable and promising biomarker of oxidative stress and could be a valid predictor of functional outcomes in patients. Monitoring of behavioral indicators along with biomarkers may have crucial benefits in translational stroke research.     

Adoptive Immunotherapy Strategies with Cytokine-Induced Killer (CIK) Cells in the Treatment of Hematological Malignancies

Cytokine-induced killer (CIK) cells are a heterogeneous population of immune effector cells that feature a mixed T- and Natural killer (NK) cell-like phenotype in their terminally-differentiated CD3⁺CD56⁺ subset. The easy availability, high proliferation rate and widely major histocompatibility complex (MHC)-unrestricted antitumor activity of CIK cells contribute to their particularly advantageous profile, making them an attractive approach for adoptive immunotherapy. CIK cells have shown considerable cytotoxicity against both solid tumors and hematological malignancies in vitro and in animal studies. Recently, initial clinical experiences demonstrated the feasibility and efficacy of CIK cell immunotherapy in cancer patients, even at advanced disease stages. Likewise, the clinical application of CIK cells in combination with standard therapeutic procedures revealed synergistic antitumor effects. In this report, we will focus our consideration on CIK cells in the treatment of hematological malignancies. We will give insight into the latest advances and future perspectives and outline the most prominent results obtained in 17 clinical studies. Overall, CIK cells demonstrated a crucial impact on the treatment of patients with hematological malignancies, as evidenced by complete remissions, prolonged survival durations and improved quality of life. However, up to now, the optimal application schedule eventually favoring their integration into clinical practice has still to be developed.     

Vitamin A and Retinoids in Bladder Cancer Chemoprevention and Treatment: A Narrative Review of Current Evidence,Challenges and Future Prospects

Bladder cancer (BC) is the tenth most common cancer worldwide with a high recurrence rate, morbidity and mortality. Therefore, chemoprevention and improved treatment of BC are of paramount importance. Epidemiological studies suggest that adequate vitamin A intake may be associated with reduced BC risk. In addition, retinoids, natural and synthetic derivatives of vitamin A, are intensively studied in cancer research due to their antioxidant properties and their ability to regulate cell growth, differentiation, and apoptosis. Findings from in vivo and in vitro models of BC show great potential for the use of retinoids in the chemoprevention and treatment of BC. However, translation to the clinical practice is limited. In this narrative review we discuss: (i) vitamin A and retinoid metabolism and retinoic acid signalling, (ii) the pathobiology of BC and the need for chemoprevention, (iii) the epidemiological evidence for the role of dietary vitamin A in BC, (iv) mechanistic insights obtained from in vivo and in vitro models, (v) clinical trials of retinoids and the limitations of retinoid use, (vi) novel systems of retinoid delivery, and (vii) components of retinoid signalling pathways as potential novel therapeutic targets.     

两款祛痘印精华的功效对比

研究了两款化妆品祛痘印精华的临床功效对比,选取30位20～40岁志愿者,随机分成两组,每组15人按要求在脸部连续使用4周祛痘印精华.利用无创仪器检测方法,分别测试受试者使用前后经皮水分流失TEWL值、皮肤白度、皮肤红度、面部卟啉的变化情况,并用VISIA-CR面部成像系统拍摄面部图片.结果显示,使用样品之后,两组志愿者...