Recognition and analysis of cell nuclear phases for high-content screening based on morphological features

Automated analysis of molecular images has increasingly become an important research in computational life science. In this paper some new and efficient algorithms for recognizing and analyzing cell phases of high-content screening are presented. The conceptual frameworks are based on the morphological features of cell nuclei. The useful preprocessing includes: smooth following and linearization; extraction of morphological structural points; shape recognition based morphological structure; issue of touching cells for cell separation and reconstruction. Furthermore, the novel detecting and analyzing strategies of feed-forward and feed-back of cell phases are proposed based on gray feature, cell shape, geometrical features and difference information of corresponding neighbor frames. Experiment results tested the efficiency of the new method.     

Fast Object Segmentation by Growing Minimal Paths from a Single Point on 2D or 3D Images

In this paper, we present a new method for segmenting closed contours and surfaces. Our work builds on a variant of the minimal path approach. First, an initial point on the desired contour is chosen by the user. Next, new keypoints are detected automatically using a front propagation approach. We assume that the desired object has a closed boundary. This a-priori knowledge on the topology is used to devise a relevant criterion for stopping the keypoint detection and front propagation. The final domain visited by the front will yield a band surrounding the object of interest. Linking pairs of neighboring keypoints with minimal paths allows us to extract a closed contour from a 2D image. This approach can also be used for finding an open curve giving extra information as stopping criteria. Detection of a variety of objects on real images is demonstrated. Using a similar idea, we can extract networks of minimal paths from a 3D image called Geodesic Meshing. The proposed method is applied to 3D data with promising results.

Complete discriminant evaluation and feature extraction in kernel space for face recognition

This work proposes a method to decompose the kernel within-class eigenspace into two subspaces: a reliable subspace spanned mainly by the facial variation and an unreliable subspace due to limited number of training samples. A weighting function is proposed to circumvent undue scaling of eigenvectors corresponding to the unreliable small and zero eigenvalues. Eigenfeatures are then extracted by the discriminant evaluation in the whole kernel space. These efforts facilitate a discriminative and stable low-dimensional feature representation of the face image. Experimental results on FERET, ORL and GT databases show that our approach consistently outperforms other kernel based face recognition methods.

An adaptive genetic-based signature learning system for intrusion detection

Rule-based intrusion detection systems generally rely on hand crafted signatures developed by domain experts. This could lead to a delay in updating the signature bases and potentially compromising the security of protected systems. In this paper, we present a biologically-inspired computational approach to dynamically and adaptively learn signatures for network intrusion detection using a supervised learning classifier system. The classifier is an online and incremental parallel production rule-based system.A signature extraction system is developed that adaptively extracts signatures to the knowledge base as they are discovered by the classifier. The signature extraction algorithm is augmented by introducing new generalisation operators that minimise overlap and conflict between signatures. Mechanisms are provided to adapt main algorithm parameters to deal with online noisy and imbalanced class data. Our approach is hybrid in that signatures for both intrusive and normal behaviours are learnt.The performance of the developed systems is evaluated with a publicly available intrusion detection dataset and results are presented that show the effectiveness of the proposed system.     

A novel self-organizing fuzzy rule-based system for modelling traffic flow behaviour

The study and development of transportation systems have been a focus of attention in recent years, with many research efforts directed in particular at modelling traffic behaviour from both macroscopic and microscopic points of views. Although many statistical regression models of road traffic relationships have been formulated, they have proven to be unsuitable due to multiple and ill-defined traffic characteristics. Alternative methods such as neural networks have thus been sought but, despite some promising results, their design remains problematic and implementation is equally difficult. Another salient issue is that the opaqueness of trained networks prevents understanding the underlying models. Hybrid neuro-fuzzy rule-based systems, which combine the complementary capabilities of both neural networks and fuzzy logic, constitute a more promising technique for modelling traffic flow. This paper describes the application of a specific class of neuro-fuzzy system known as the Pseudo Outer-Product Fuzzy-Neural Network using Truth-Value-Restriction method (POPFNN-TVR) for modelling traffic behaviour. This approach has been shown to perform better on such problems than similar architectures. The results obtained highlight the capability of POPFNN-TVR in fuzzy knowledge extraction for modelling inter-lane relationships in a highway traffic stream, as well as in generalizing from sample data, as compared to traditional feed-forward neural networks using back-propagation learning. The model thus obtained automatically can be understood, analysed, and readily applied for transportation planning.     

利用ETM数据进行矿化蚀变信息提取的方法研究——以柴北缘地区为例

在柴北缘地区利用ETM数据进行遥感矿化蚀变信息提取方法研究主要基于三个方面：①研究区蚀变信息及背景干扰地物信息的光谱特征;②矿化蚀变信息提取的最佳变量集组合;③图像增强处理方法和流程。在综合分析研究的基础上,采用“图像掩膜→最佳变量组合→波段比值→主成分分析→阈值分割→多元数据综合分析及异常筛选”的方法和流程提取了柴北缘成矿带的矿化蚀变异常信息,为该区综合成矿预测提供了可靠依据。     

一种大规模数据的快速潜在语义索引

潜在语义索引（LSI）已应用到现代信息检索的多个领域,但矩阵奇异值分解的高复杂度阻碍了该技术在大规模数据上的应用。提出一种大规模数据的快速LSI方法。给出一个降维问题的统一框架,LSI作为一种特征提取算法,可以在这个框架下转化为一个特征选择问题。利用该技术在最大程度保持LSI降维效果的同时,简化LSI的计算,使其能够应用于大规模数据。