铜金粉的颜色及其影响因素

利用分光光度计对国内外铜金粉的颜色进行了测试，研究了铜金粉的成分、微观状态对颜色的影响。结果表明：铜金粉颜色可以用色彩三要素进行描述，其中铜金粉的色相只与合金成分有关，而与铜金粉片的大小、形状及粒度分布无关；明度和纯度与铜金粉片在油墨层中定向排列状态、片的大小、形状及粒度分布有关，而与成分无关；合金成分的微小波动不会引起铜金粉色相的明显改变。     

碾压混凝土中石粉含量精确控制研究与应用

通过在碾压混凝土中掺入工业化粉磨加工的石粉代替部分砂,使砂中石粉总含量满足碾压混凝土的要求,从而改善碾压混凝土的性能,保证其质量.从不同石粉含量的碾压棍凝土试验研究结果分析,以及金安桥水电站大坝碾压混凝土施工质量控制结果分析可知,混凝土生产时必须对外掺石粉量进行精确控制,确保掺入代砂石粉后石粉总量不变,才能确保碾压混凝土的质量稳定.     

规格石爆破施工技术及实践

为解决采石工程中爆破产生的大量石粉不能满足石料粒径要求的问题,采用不耦合装药方式的规格石爆破技术,对降低石粉含量、提高石料的利用率效果显著。通过某采石工程的应用,结合低爆速炸药的应用,达到了减少弃料、降低开采投资成本的目的。     

亭子口水利枢纽左岸天然料砂石加工系统设计

亭子口水利枢纽选用天然砂砾石料场作为混凝土骨料的料源,其骨料加工系统的生产工艺流程较人工山场料加工系统工艺流程更为复杂。详细介绍了该电站左岸天然砂石料加工系统的设计要点,对系统的工艺流程做了深入的研究,选择了适合其生产能力的加工设备,并首次在水电工程中采用梯形磨磨制石粉新工艺。实践证明,该系统的设计是成功的,其生产能力和骨料加工质量满足工程需求。     

Mechanical activation-assisted electro-thermal explosion synthesis of the Ti2AlC phase

This study deals with the synthesis of the Ti₂AlC phase using the Electro-Thermal Explosion under Pressure with Confinement (ETEPC) technique. The effects of the ETEPC technique and the milling process parameters on the TiC_x phase content and the formation mechanism of the Ti₂AlC phase were investigated. The latter is mainly affected by the morphology of the powder mixture and aluminum melted amount. The optimization of the above parameters allowed the achievement of the desired reaction, leading to the formation of the Ti₂AlC phase with a purity of about 97?wt%. The results clearly demonstrate that the ETEPC process enables one to control both time and material synthesis temperature.     

Recent progress in continuous and semi-continuous processing of solid oral dosage forms: a review

Context: Continuous processing is an innovative production concept well known and successfully used in other industries for many years. The modern pharmaceutical industry is facing the challenge of transition from a traditional manufacturing approach based on batch-wise production to a continuous manufacturing model.

Objective: The aim of this article is to present technological progress in manufacturing based on continuous and semi-continuous processing of the solid oral dosage forms.

Methods: Single unit processes possessing an alternative processing pathway to batch-wise technology or, with some modification, an altered approach that may run continuously, and are thus able to seamlessly switch to continuous manufacturing are briefly presented. Furthermore, the concept of semi-continuous processing is discussed. Subsequently, more sophisticated production systems created by coupling single unit processes and comprising all the steps of production, from powder to final dosage form, were reviewed. Finally, attempts of end-to-end production approach, meaning the linking of continuous synthesis of API from intermediates with the production of final dosage form, are described.

Results: There are a growing number of scientific articles showing an increasing interest in changing the approach to the production of pharmaceuticals in recent years. Numerous scientific publications are a source of information on the progress of knowledge and achievements of continuous processing. These works often deal with issues of how to modify or replace the unit processes in order to enable seamlessly switching them into continuous processing. A growing number of research papers concentrate on integrated continuous manufacturing lines in which the production concept of “from powder to tablet” is realized. Four main domains are under investigation: influence of process parameters on intermediates or final dosage forms properties, implementation of process analytical tools, control-managing system responsible for keeping continuous materials flow through the whole manufacturing process and the development of new computational methods to assess or simulate these new manufacturing techniques. The attempt to connect the primary and secondary production steps proves that development of continuously operating lines is possible.

Conclusion: A mind-set change is needed to be able to face, and fully assess, the advantages and disadvantages of switching from batch to continuous mode production.     

斯蒂芬酸铅含量对某型雷管作用可靠性的影响?

为解决某型雷管瞎火、半爆的问题,分析了工艺过程对针刺药组分和其中斯蒂芬酸铅含量的影响。试验结果表明,工艺过程中针刺药分药和回倒环节会引起针刺药中铅钡共晶含量的波动,当铅钡共晶中斯蒂芬酸铅的含量较低时会导致雷管作用失效。通过建立斯蒂芬酸铅含量与雷管作用可靠性的关系,合理解释了故障批产品几个异常现象,指出应通过使用较小的盒子盛装针刺药等措施来确保生产过程受控。     

珍珠层粉/壳聚糖多孔支架的制备及分析测试

用负压真空冷冻干燥机在-20℃条件下冷冻干燥48h制备珍珠层粉/壳聚糖复合多孔支架。用扫描电子显微镜(SEM)观察支架表面形貌,通过X射线衍射分析(XRD)、傅里叶红外光谱(FTIR)等手段对材料进行表征测试,检测其降解性能,并将兔骨髓间充质干细胞与支架共培养检测材料细胞毒性。结果表明复合支架具有稳固的三维多孔结构,孔隙率最大至91.64%,孔径在100~300μm范围,降解性能适宜,且冷冻干燥制备方法对珍珠层粉的结构无明显破坏,并具有良好的生物相容性,有利于细胞的生长。     

一种新型导爆管下药系统的研究?

当前导爆药下药工艺普遍依靠药剂自重完成,存在管体药剂分布不均、爆速波动较大的问题。针对此问题,设计了依靠下药游标精确控制下药量的一种新型下药系统。下药游标采用变频电机驱动,设计了定容药槽,可根据不同的拉制速度调整游标转速,精确且方便地控制下药量;另通过一种新的检测方法(失重法),实时测量导爆管每米的药量,从而提高导爆管质量。     

泡沫铝三明治板的研究与应用进展

泡沫铝三明治板(Aluminum foam sandwich,AFS)是基于泡沫铝材料开发的一类材料-结构一体化的先进多孔复合结构。AFS是交通运输、建筑以及航空航天等装备结构轻量化的重要材料,具有广阔的应用前景。概述了AFS的几类制备技术的基本原理和研究现状,着重分析了复合预制体制备、合金成分、AFS发泡成型工艺等关键环节中存在的理论和技术难点。介绍了AFS作为结构材料和功能材料的典型应用案例;最后总结提出了AFS材料研究和工程化技术开发的关键点与突破途径。