坦克设计新发展

本文提出“针对式坦克发展战略”主要内容,它要求“突破性新概念高新技术”,获得“减法设计方法”,因而形成“坦克发展新道路”.运用“系统总体取胜”的系统工程理论,处理好坦克全系统“综合”、全系统与分系统“配置”、分系统与分系统“匹配”、全系统与人及作战环境“适应”四大关系,以“相互同水平组合”替代“单项高水平爬坡”.通过“从系统总体着眼、由边际零部件突破”的途径,善于从各个部分或部件之间的结合部加以突破,实现坦克设计新发展.     

Boosting the confidence of new product development teams: The role of team boundary spanning,team size and functional diversity

In today's highly interconnected, uncertain and dynamic business environment, team boundary spanning has become an important determinant of the performance of new product development (NPD) projects. Despite the positive evidence supporting the use of boundary spanning activities by NPD teams, little is still known about how boundary spanning teams become high-performance teams. The current study advances research on this subject by examining the mediating effect of team potency on the relationship between team boundary spanning and new product performance, as well as the moderating effects of team size and functional diversity on the relationship between team boundary spanning and team potency. Data from a time-lagged survey study of 140 NPD projects found that team boundary spanning can promote team potency that, in turn, results in greater new product quality and new product creativity. The positive effect of team boundary spanning on team potency was found to be more pronounced for NPD teams of medium size and high levels of functional diversity.     

我国爆破行业发展面临的问题与思考

针对行业发展存在的相关问题与困难,为适应新形势的要求,从国内外经济形势的发展现状出发,阐述了国际经济全球化面临的挑战以及国内经济减速等影响我国爆破行业发展的新形势,对我国爆破行业的发展现状困难与机遇进行了深入分析,特别是对以互联网、大数据和云计算为代表的信息技术以及人工智能的发展对爆破行业即将带来的深刻影响进行了探讨。对当前影响我国爆破行业发展的外部环境、内部机制、监管尺度等相关问题进行了深入思考,提出了调整爆破行业结构、促进企业转型升级、推进企业信息化建设和国际化进程等解决之道,并对主管部门、行业组织如何在推进行业结构调整、企业转型升级中发挥更大作用提出建议。     

Drug self-assembly: A phenomenon at the nanometer scale with major impact in the structure–biological properties relationship and the treatment of disease

Under water-rich conditions, small amphiphilic and hydrophobic drug molecules self-assemble into supramolecular nanostructures. Thus, substantial modifications in their interaction with cellular structures and the ability to reach intracellular targets could happen. Additionally, drug aggregates could be more toxic than the non-aggregated counterparts, or vice versa. Moreover, since self-aggregation reduces the number of effective “monomeric” molecules that interact with the target, the drug potency could be underestimated. In other cases, the activity could be ascribed to the non-aggregated molecule while it stems from its aggregates. Thus, drug self-assembly could mislead from drug throughput screening assays to advanced preclinical and clinical trials. Finally, aggregates could serve as crystallization nuclei. The impact that this phenomenon has on the biological performance of active compounds, the inconsistent and often controversial nature of the published data and the need for recommendations/guidelines as preamble of more harmonized research protocols to characterize drug self-aggregation were main motivations for this review. First, the key molecular and environmental parameters governing drug self-aggregation, the main drug families for which this phenomenon and the methods used for its characterization are described. Then, promising nanotechnology platforms investigated to prevent/control it towards a more efficient drug development process are briefly discussed.     

新型城镇化语境下的阿拉善地毯传统技艺探析

目的研究阿拉善地毯传统技艺传承与保护现状。方法通过田野调查个案并结合民俗学、艺术学的理论对阿拉善地毯进行探析。结论了解新型城镇化进程中该项技艺的生存情况,考察它的传承与保护现状,审视它面临的困境与机遇,分析并探究它的传承与保护对策是极具理论价值与现实意义的。     

Managing sequential ambidexterity in the electronics industry: roles of temporal switching capability and contingent factors

Researchers on organisational ambidexterity have proposed several solutions to address the potential conflicts between exploration activities and exploitation activities. Unlike simultaneous ambidexterity, sequential ambidexterity – defined as temporal switching between exploration and exploitation – has not been examined fully, and the conditions under which this temporal switching can be successful are unclear. This paper proposes the concept of temporal switching capability to better understand the process by which sequential ambidexterity is executed. In addition, we hypothesise that performance effects are contingent upon firm-specific factors: a firm’s business strategy and absorptive capacity. Utilising three sources of data – a secondary database, annual reports and a survey administered to 145 firms in the electronics industry with 10-year observations – we find support for our hypotheses. The results show that the temporal switching capability positively relates to new product performance and that business strategy type and absorptive capacity have moderating effects. The results are meaningful in both theory and practice.     

2010年我国恶意代码新特点的研究

文章以公安部2010年计算机病毒疫情调查活动的数据作为基础,以国家计算机病毒应急处理中心国家级恶意代码样本库作为支撑,结合信息网络安全通报机制成员单位汇总的情况和各反病毒研究机构发布的安全报告,阐述了2010年我国恶意代码发展的总体情况,分析了2010年我国恶意代码出现的新特点,探索了今后恶意代码的发展趋势并提出对策建议。     

新型军械装备损坏程度评估方法研究

根据新型军械装备损坏程度具有不确定性的特点,提出了基于D-S证据理论的新型军械装备损坏程度评估方法,并求出了新型军械装备损坏程度区分.通过对典型新型军械装备损坏程度的评估,验证了该方法的有效性和实用性.     

New Generations: Sequencing Machines and Their Computational Challenges

New generation sequencing systems are changing how molecular biology is practiced. The widely promoted ＄1000 genome will be a reality with attendant changes for healthcare, including personalized medicine. More broadly the genomes of many new organisms with large samplings from populations will be commonplace. What is less appreciated is the explosive demands on computation, both for CPU cycles and storage as well as the need for new computational methods. In this article we will survey some of these develo...     

面向股票新闻的情感分类方法

互联网新闻资讯对证券市场和投资者有举足轻重的影响,新闻进行情感分类后再展示给用户,可以帮助投资者迅速做出投资决定.从文本分类的基本方法出发,实现了基于N-gram 统计模型的新词发现方法,并将所得结果用于构建中文分词词典和情感词典.同时引入评价理论,并用朴素贝叶斯、K 近邻和支持向量机3 种方法进行股票新闻标题的情感分类实验.所用实验数据来自2009 年“新浪财经”共计23 万余条的新闻标题,结果表明二分类的准确率最高可达82.9%.此外,还实现了一个原型系统用于展示股票新闻的分类结果.