Note on the use of the term subject in pre-1886 discussions of thought-transference experiments.

In response to K. Danzinger's (see record 1986-00068-001) suggestion that the first use of the term subject in the English-language psychological literature occurred in 1886 in the context of experiments involving the hypnotic state, the present author points out that there are examples of the use of the term in discussions of experiments on thought transference published by the Society for Psychical Research in the 1880's. (8 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

智能化磁控谐振高压试验系统研究

目前电网智能化水平的提升对高压试验的智能化和试验效率也有了更高的需求,为解决现有的高压试验电源在高压交流绝缘试验中存在的不足,提升高压试验的效率,提出了一种智能化磁控谐振高压试验系统。该试验系统集升压、补偿和调谐于一体,具有升压调节平滑连续,结构紧凑等优势,可用于工频耐压试验。阐述了该系统的结构组成与基本原理,并搭建了该试验系统仿真模型,通过研究空载和负载运行特性验证了该系统原理的正确性。     

Characterization and Reconstitution of Human Lipoyl Synthase (LIAS) Supports ISCA2 and ISCU as Primary Cluster Donors and an Ordered Mechanism of Cluster Assembly

Lipoyl synthase (LIAS) is an iron–sulfur cluster protein and a member of the radical S-adenosylmethionine (SAM) superfamily that catalyzes the final step of lipoic acid biosynthesis. The enzyme contains two [4Fe–4S] centers (reducing and auxiliary clusters) that promote radical formation and sulfur transfer, respectively. Most information concerning LIAS and its mechanism has been determined from prokaryotic enzymes. Herein, we detail the expression, isolation, and characterization of human LIAS, its reactivity, and evaluation of natural iron–sulfur (Fe–S) cluster reconstitution mechanisms. Cluster donation by a number of possible cluster donor proteins and heterodimeric complexes has been evaluated. [2Fe–2S]-cluster-bound forms of human ISCU and ISCA2 were found capable of reconstituting human LIAS, such that complete product turnover was enabled for LIAS, as monitored via a liquid chromatography–mass spectrometry (LC–MS) assay. Electron paramagnetic resonance (EPR) studies of native LIAS and substituted derivatives that lacked the ability to bind one or the other of LIAS’s two [4Fe–4S] clusters revealed a likely order of cluster addition, with the auxiliary cluster preceding the reducing [4Fe–4S] center. These results detail the trafficking of Fe–S clusters in human cells and highlight differences with respect to bacterial LIAS analogs. Likely in vivo Fe–S cluster donors to LIAS are identified, with possible connections to human disease states, and a mechanistic ordering of [4Fe–4S] cluster reconstitution is evident.     

Qualitative and Quantitative Comparison of Plasma Exosomes from Neonates and Adults

Exosomes are extracellular vesicles that contain nucleic acids, lipids and metabolites, and play a critical role in health and disease as mediators of intercellular communication. The majority of extracellular vesicles in the blood are platelet-derived. Compared to adults, neonatal platelets are hyporeactive and show impaired granule release, associated with defects in Soluble N-ethylmaleimide-sensitive fusion Attachment protein REceptor (SNARE) proteins. Since these proteins participate in biogenesis of exosomes, we investigated the potential differences between newborn and adult plasma-derived exosomes. Plasma-derived exosomes were isolated by ultracentrifugation of umbilical cord blood from full-term neonates or peripheral blood from adults. Exosome characterization included size determination by transmission electron microscopy and quantitative proteomic analysis. Plasma-derived exosomes from neonates were significantly smaller and contained 65% less protein than those from adults. Remarkably, 131 proteins were found to be differentially expressed, 83 overexpressed and 48 underexpressed in neonatal (vs. adult) exosomes. Whereas the upregulated proteins in plasma exosomes from neonates are associated with platelet activation, coagulation and granule secretion, most of the underexpressed proteins are immunoglobulins. This is the first study showing that exosome size and content change with age. Our findings may contribute to elucidating the potential “developmental hemostatic mismatch risk” associated with transfusions containing plasma exosomes from adults.     

灰铸铁几个关键技术问题的探讨

对灰铸铁熔炼中的几个关键问题进行探讨：1）锰、硫对灰铸铁力学性能及切削加工性能的影响；2）硬质点颗粒对断屑性能的影响；3）时效处理对高速切削时刀具寿命的影响；4）如何减小高强度灰铸铁的收缩倾向；5）如何生产HT350及更高牌号的灰铸铁。     

基于微生物菌种资源库的图像智能检索系统研究*

在建设微生物菌种资源平台的基础上, 设计开发微生物菌种资源数据库管理系统,实现基于内容的Web图像智能检索系统.该检索系统采用B/S体系架构,可根据微生物菌种文本信息或图像的形状、纹理和颜色特征进行检索,有效提高了微生物菌种图像信息搜索的查准率、查全率和查找速度.     

板料成形模拟后处理中的截面物理量的显示技术*

在自行开发的板料成形有限元后置处理系统FASTAMP_POST中,采用了动态获取截面物理量的算法,实现了截面物理量实时显示功能。该功能真实反映了网格物理量的大小及其变化趋势,具有原理简单、易实现、执行速度快的优点。     

A panoramic view of Li7P3S11 solid electrolytes synthesis,structural aspects and practical challenges for all-solid-state lithium batteries

The development of an inorganic electrochemical stable solid-state electrolyte is essentially responsible for future state-of-the-art all-solid-state lithium batteries (ASSLBs). Because of their advantages in safety, working temperature, high energy density, and packaging, ASSLBs can develop an ideal energy storage system for modern electric vehicles (EVs). A solid electrolyte (SE) model must have an economical synthesis approach, exhibit electrochemical and chemical stability, high ionic conductivity, and low interfacial resistance. Owing to its highest conductivity of 17 mS·cm^-1, and deformability, the sulfide-based Li₇P₃S₁₁ solid electrolyte is a promising contender for the high-performance bulk type of ASSLBs. Herein, we present a current glimpse of the progress of synthetic procedures, structural aspects, and ionic conductivity improvement strategies. Structural elucidation and mechanistic approaches have been extensively discussed by using various characterization techniques. The chemical stability of Li₇P₃S₁₁ could be enhanced via oxide doping, and hard and soft acid/base (HSAB) concepts are also discussed. The issues to be undertaken for designing the ideal solid electrolytes, interfacial challenges, and high energy density have been discoursed. This review aims to provide a bird's eye view of the recent development of Li₇P₃S₁₁-based solid-state electrolyte applications and explore the strategies for designing new solid electrolytes with a target-oriented approach to enhance the efficiency of high energy density all-solid-state lithium batteries.     

基于长短期记忆网络的电网故障区域定位与故障传播路径推理

为了在发生故障后维持电力系统的安全稳定,有必要实现对故障区域的快速定位并确定故障冲击的传播路径,提出基于长短期记忆网络(LSTM)的故障区域定位和故障传播路径推理方法.首先,利用LSTM建立2个故障诊断模型分别实现在线检测故障时刻和确定故障区域;然后,通过计算故障点附近线路的端口供给能量确定故障冲击的传播路径;最后,以8机36节点电网为例进行算例验证,结果表明所提模型可在发生故障后短时间内检测到故障,给出故障区域和故障冲击传播的路径,且对噪声有较强的鲁棒性.