LCC谐振充电IGBT开关Marx发生器

为满足Marx发生器的充放电脉冲工作要求,提出采用恒导通时间-恒频率控制策略的LCC串并联谐振变换器作为IGBT开关Marx发生器的充电电源.利用Pspice软件和等效模型模态方法对断续模式工作的LCC变换器实现软开关的原理进行分析,给出设计原则.仿真结果表明变换器能够以较高效率满足Marx发生器从短路到开路的宽范围变动工作特性的充电要求,实现高达1kHz重复频率变频变脉宽稳定运行.所提出的方法为研发制造紧凑型一体化高重复频率Marx发生器式功率脉冲电源开辟了一条新路.     

Assessing the Effects of Acute Amyloid β Oligomer Exposure in the Rat

Alzheimer’s disease (AD) is the most common form of dementia, yet there are no therapeutic treatments that can either cure or delay its onset. Currently, the pathogenesis of AD is still uncertain, especially with respect to how the disease develops from a normal healthy brain. Amyloid β oligomers (AβO) are highly neurotoxic proteins and are considered potential initiators to the pathogenesis of AD. Rat brains were exposed to AβO via bilateral intracerebroventricular injections. Rats were then euthanized at either 1, 3, 7 or 21-days post surgery. Rat behavioural testing was performed using the Morris water maze and open field tests. Post-mortem brain tissue was immunolabelled for Aβ, microglia, and cholinergic neurons. Rats exposed to AβO showed deficits in spatial learning and anxiety-like behaviour. Acute positive staining for Aβ was only observed in the corpus callosum surrounding the lateral ventricles. AβO exposed rat brains also showed a delayed increase in activated microglia within the corpus callosum and a decreased number of cholinergic neurons within the basal forebrain. Acute exposure to AβO resulted in mild learning and memory impairments with co-concomitant white matter pathology within the corpus callosum and cholinergic cell loss within the basal forebrain. Results suggest that acute exposure to AβO in the rat may be a useful tool in assessing the early phases for the pathogenesis of AD.     

高重复率下硅酸镓镧电光晶体压电特性有限元分析

介绍了在高重复率高电压的载荷下,以硅酸镓镧为例的电光晶体的压电特性。建立了电光晶体的有限元模型,并基于有限元数值方法,模拟分析了在固定和自由边界条件下硅酸镓镧晶体由逆压电效应产生的应变及应力。结果表明:自由边界条件下的晶体形变是呈线性变化的;固定边界条件下晶体有明显的位移变化,且其形变相对于晶体中心处呈对称分布,由于加在晶体的电压数值分布不同,晶体周围区域比中心区域的形变更为严重。晶体在自由边界条件下产生的应力远远小于固定边界条件下产生的应力。     

陶瓷微滤膜回收偏钛酸过程中反冲技术研究

对陶瓷微滤膜加嘏偏钛酸颗粒过程中应用反冲技术控制膜污染进行了研究,观察了反冲压力、时间和周期对反冲效果的影响,确定了合适的反冲条件;比较了有无反冲存在下,操作参数对膜通量及其下降情况的影响;考察了反冲过程的重复性;探讨了反冲过程的机理,对陶瓷膜回收偏钛酸过程中反部诉成功及此的过程的工业化应用有重要的意义。     

Learning correct responses and errors in the Hebb repetition effect: Two faces of the same coin.

In a serial recall task, the Hebb repetition effect occurs when recall performance improves for a sequence repeated throughout the experimental session. This phenomenon has been replicated many times. Nevertheless, such cumulative learning seldom leads to perfect recall of the whole sequence, and errors persist. Here the authors report evidence that there is another side to the Hebb repetition effect that involves learning errors produced in a repeated sequence. A learning measure based on past recalls (correct or incorrect) shows that the probability of a given response increases with the number of prior occurrences of that response. The pattern of results reveals another manifestation of the Hebb repetition effect and speaks to the nature of implicit learning. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Preparatory processes in the task-switching paradigm: Evidence from the use of probability cues.

The purpose of the investigations was to dissociate processes of task preparation from task execution in the task-switching paradigm. The basic assumption was that task repetitions have 2 advantages over task shifts: an activation advantage as a result of the execution of the same task type in the pretrial, and an expectation advantage, because participants, in general, implicitly expect a repetition. In Experiments 1-3, the authors explicitly manipulated expectancies by presenting cues that announced a shift and/or a repetition with probabilities of 1.00, .75, .50, or .25. Increasing latencies with decreasing probability for shifts and repetitions show that the expectation advantage can be equalized by preparation. However, the activation advantage represented by constant shift costs between tasks of the same probability is not penetrable by preparation. In Experiments 4 and 5, the authors found evidence that preparation involves activation of the expected task and inhibition of distracting tasks. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Cognitive skill acquisition and transfer in younger and older adults.

The acquisition of cognitive skills often depends on 1 of (or a combination of) 2 processes, the execution of an algorithm, and the retrieval of problem instances. This study examined the effects of age and repetition of problem instances on the production and verification of solutions to 2 serially presented sets of alphabet arithmetic problems. Analyses of the parameters derived from power-function fits for individuals revealed age differences favoring young adults in improvement span, learning rate, and asymptote. For both age groups, the beneficial effects of repetitions on 1st-set response times were attributable to algorithmic speedup and to the retrieval of instances, whereas improvements in the speed of 2nd-set response times were attributable primarily to item retrieval. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Processes underlying long-term repetition priming in digit data entry.

Two experiments examined long-term repetition priming in data entry. In each experiment, participants entered 4-digit numbers displayed as either words or numerals, and responded with digits (Experiment 1), or either digits or initial letters (Experiment 2). At test 1 week later, they entered old and new numbers, with the format changed for half of the old stimuli. Implicit memory was evidenced at test by faster entry of the old than the new numbers, regardless of whether the numbers were in the same or different format, suggesting that the abstract numerical meaning, not the surface form, contributes to repetition priming. Numbers presented as words in training had an advantage over numbers presented as numerals, regardless of response format, implying that type of processing also contributes to the effect and ruling out an explanation based on time spent processing numbers in word format. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Within- and between-language priming differ: Evidence from repetition of pictures in Spanish-English bilinguals.

In the current study, the authors used an immediate repetition paradigm with pictures to observe whether repetition enhances word production in bilinguals. In Experiment 1, participants were asked to name pictures that were named previously in the same language (Spanish-Spanish or English-English) or in the opposite language (Spanish-English or English-Spanish). Results revealed a repetition effect both within languages and between languages. Furthermore, there was an asymmetry within language, with repetition priming being larger in Spanish than in English. Experiments 2 and 3 revealed that lag interacted with language for both within- and between-language priming. However, lag resulted in a decrease in the asymmetry for within- but not between-language priming. The results are consistent with the view that within- and between-language repetition priming are mediated by different mechanisms. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Repetition blindness, forward and backward.

In these experiments, 2 letters were presented sequentially to the left and right of fixation, followed by pattern masks. Report was cued by spatial location (Experiments 1a, 1b, 2, 4, and 5) or temporal position (Experiments 3, 4, and 5). In all experiments, 2 identical letters on a trial resulted in reduced accuracy of report (repetition blindness; RB) for both the 1st and 2nd presented letters. This decrement was greater for the 2nd letter if subjects expected temporal cues, but tended to be greater for the Ist letter if they expected spatial cues. Analyses of errors and responses on catch trials indicated no bias against report of repetitions, and the repetition decrement did not interact with output order. The data are inconsistent with both type-refractoriness and memory-retrieval accounts of RB. A modified version of N. G. Kanwisher's (1987) token-individuation theory is proposed to account for the results. (PsycINFO Database Record (c) 2010 APA, all rights reserved)