The Inflammatory Profile of Obesity and the Role on Pulmonary Bacterial and Viral Infections

Obesity is a globally increasing health problem, entailing diverse comorbidities such as infectious diseases. An obese weight status has marked effects on lung function that can be attributed to mechanical dysfunctions. Moreover, the alterations of adipocyte-derived signal mediators strongly influence the regulation of inflammation, resulting in chronic low-grade inflammation. Our review summarizes the known effects regarding pulmonary bacterial and viral infections. For this, we discuss model systems that allow mechanistic investigation of the interplay between obesity and lung infections. Overall, obesity gives rise to a higher susceptibility to infectious pathogens, but the pathogenetic process is not clearly defined. Whereas, viral infections often show a more severe course in obese patients, the same patients seem to have a survival benefit during bacterial infections. In particular, we summarize the main mechanical impairments in the pulmonary tract caused by obesity. Moreover, we outline the main secretory changes within the expanded adipose tissue mass, resulting in chronic low-grade inflammation. Finally, we connect these altered host factors to the influence of obesity on the development of lung infection by summarizing observations from clinical and experimental data.     

Dynamics of Bacterial Community Structure in the Rhizosphere and Root Nodule of Soybean: Impacts of Growth Stages and Varieties

Bacterial communities in rhizosphere and root nodules have significant contributions to the growth and productivity of the soybean (Glycine max (L.) Merr.). In this report, we analyzed the physiological properties and dynamics of bacterial community structure in rhizosphere and root nodules at different growth stages using BioLog EcoPlate and high-throughput sequencing technology, respectively. The BioLog assay found that the metabolic capability of rhizosphere is in increasing trend in the growth of soybeans as compared to the bulk soil. As a result of the Illumina sequencing analysis, the microbial community structure of rhizosphere and root nodules was found to be influenced by the variety and growth stage of the soybean. At the phylum level, Actinobacteria were the most abundant in rhizosphere at all growth stages, followed by Alphaproteobacteria and Acidobacteria, and the phylum Bacteroidetes showed the greatest change. But, in the root nodules Alphaproteobacteria were dominant. The results of the OTU analysis exhibited the dominance of Bradyrhizobium during the entire stage of growth, but the ratio of non-rhizobial bacteria showed an increasing trend as the soybean growth progressed. These findings revealed that bacterial community in the rhizosphere and root nodules changed according to both the variety and growth stages of soybean in the field.     

Effects of sulfate-reducing bacteria on the corrosion behavior of carbon steel

The influences of the growing process of sulfate-reducing bacteria (SRB) in seawater system on the medium state and corrosion behavior of carbon steel were studied by detecting solution state parameters and using corrosion electrochemical methods. The growing process of SRB in the seawater shows the three stages of growing, death and residual phases. The solution state parameters of the concentration of sulfide, the pH value and the redox potential changed during the three stages of the SRB growing process. And the corrosion rate of D36 carbon steel was accelerated during the growing phase and stable during the death and residual phases. The results indicate that the medium state and the corrosion rate of the steel do not depend on the number of active SRB, but depend on the accumulation of the metabolism products of SRB.     

免水型生态卫生设施用降解菌的分离筛选

本文对免水型生态卫生设施中的生物填料及施有机肥农田的土壤进行了人类粪便降解菌的分离。筛选得到的各菌种在实验条件下，降解粪便效果较好，除臭除味，COD下降率在30％左右。其中在土壤中分离出来的9号菌，COD下降率达41％，全部菌种复合培养处理的下降率高达59％。结果表明，实验采用的分离筛选方法是比较有效的，筛选得到了具有较好降解效果的菌种，为降解菌的进一步试验打下了基础。     

离散型细菌觅食算法求解TSP

旅行商问题(TSP)是组合优化问题的典型代表,针对TSP的求解提出一种离散型细菌觅食(DBFO)算法.该算法通过结合2-opt算法设计了一种适合处理离散型变量的趋化算子,将细菌觅食算法推广到了离散情形.同时,结合TSP的特点,在迁徙算子中引入基因库的思想来指导新个体的生成,提高了算法的搜索效率.通过对TSPLIB标准库中22个实例进行仿真实验.实验结果表明,该算法能够有效求解城市规模500以下的TSP,与混合蚁群算法和离散型萤火虫群算法相比,具有更好的全局收敛性和稳定性.     

油田废水电解杀菌研究

采用电解杀菌技术处理油田废水，研究了电解时间、电流强度、极板间距以及电极联结方式等因素对废水中硫酸盐还原菌杀灭效果的影响。结果表明，油田废水经3min电解杀菌，硫酸盐还原菌杀灭率高达99．90％。随着电解时间的增加，硫酸盐还原菌的杀菌率进一步提高；电流强度增加，硫酸盐还原菌的杀灭率升高。在电流强度保持不变的情况下，随着极板间距增加，极板之间电压升高，更有利于杀灭硫酸盐还原菌。在极板间电流强度相同的条件下，两种电极联结方式的杀菌率差别不大，杀菌率均在99．9％以上。     

A2O工艺缺氧生物磷去除

A lab-scale anaerobic-anoxic-oxic （A^2O） process used to treat a synthetic brewage wastewater was investigated. The objectives of the study were to identify the existence of denitrifying phosphorus removing bacteria （DPB）, evaluate the contribution of DPB to biological nutrient removal and enhance the denitrifying phosphorus removal in A^2O bioreactors. Sludge analysis confirmed that the average anoxic P uptake accounted for approximately 70% the total amount of P uptake, and the ratio of anoxic P uptake rate to aerobic P uptake rate was 69%. In addition, nitrate concentration in the anoxic phase and different organic substrate introduced into the anaerobic phase had significant effect on the anoxic P uptake. Compared with conventional A^2O processes, good removal efficiencies of COD, phosphorus, ammonia and total nitrogen （92.3%, 95.5%, 96% and 79.5%, respectively） could be achieved in the anoxic P uptake system, and aeration energy consumption was saved 25%. By controlling the nitrate recirculation flow in the anoxic zone, anoxic P uptake could be enhanced, which solved the competition for organic substrates among poly-P organisms and denitrifiers successfully under the COD limiting conditions. Therefore, in wastewater treatment plants the control system should be applied according to the practical situation to optimize the operation.     

Corrosion of 2205 duplex stainless steel in chloride medium containing sulfate-reducing bacteria

Sulfate-reducing bacteria (SRB) play significant role in the corrosion of stainless steels exposed to marine and soil environment. Sulfate reduction by bacterial species results in the production of H₂S, which can significantly influence the anodic and cathodic processes and ultimately enhances the corrosion of materials. In the present study, 2205 type duplex stainless steel (DSS) coupons in solution-annealed condition were exposed to chloride medium containing SRB species, Desulfovibrio desulfuricans, for 40 days and examined by microscopy. Etching of the duplex structure, pitting as well as crevice attack were noticed. Similar results were obtained by microscopic studies with coupons exposed for 14 days in medium containing SRB followed by anodic polarization. SEM studies, of crevices observed after anodic polarization, indicated that the attack was initiated at the grain boundaries and slowly encroached into austenite grains. The initiation of attack was also evident from AFM studies of coupon exposed under freely corroding conditions for 7 days. ESCA studies reveal that under anaerobic conditions of SRB growth sulfidation of passive film occurs. The modified passive film found to depolarize the cathodic reactions. The nature and mechanism of SRB attack on DSS and possibility of detection at early stages were discussed.     

白腐真菌处理阿维菌素废水优势菌种筛选研究

建立了白腐真菌处理阿维菌素废水优势菌种的筛选方法.经富集、分离、纯化、筛选得到4株优势菌株,并对优势菌株进行了生理生化特性的研究.     

改进的细菌觅食优化算法

细菌觅食优化算法是一种受大肠杆菌觅食现象启发产生的一种群体进化算法,该算法具有良好的全局优化能力,鲁棒性强,算法简单等优点,但其也存在易早熟,收敛速度慢等缺点. 根据其缺点,提出了一种改进的细菌觅食优化算法,改进后的算法收敛速度加快,在一定程度上避免了易早熟的缺点. 将原算法和改进算法应用于PID参数的在线自整定,通过matlab仿真实验证明了算法改进后的优越性.