U71Mn钢轨闪光焊焊后火焰正火与感应正火接头性能对比

通过对U71Mn闪光焊经火焰正火和感应正火处理后的接头进行拉伸、冲击及硬度试验,对比两种正火方式对上述性能的影响.研究认为感应正火更有利于提高U71Mn钢轨闪光焊焊后接头性能.     

FANUC与华中HNC-21/22T系统G71指令格式和应用的区别

FANUC 0 i系统的数控车床和华中HNC-21/22T系统的数控车床都具有复合车削循环功能,能简化程序编制,但2种系统的指令使用时存在着不同,以示例方式介绍G71指令在编程格式、编程要求及应用上的不同。     

Anti/pro-oxidative properties of selected standard chemicals and tea extracts investigated by DNA-based electrochemical biosensor

A DNA-modified screen-printed carbon electrode and the [Co(phen)₃]³⁺ complex as an electrochemical DNA marker were used for the evaluation of anti/pro-oxidative properties of -tocopherol, -carotene, quercetin, kaempferol and myricetin, as well as various tea extracts. Reactive oxygen species were generated using a model cleavage mixture composed of 5×10^–7 M [Cu(phen)₂]²⁺ as the catalyst, 1×10^–3 M ascorbic acid as the chemical reductant and air oxygen as the natural oxidant. The antioxidative activity of standard chemicals increases with their concentration, reaching a maximum where prooxidative behaviour becomes of importance. Antioxidative effects of tea exctracts varied with the temperature of their preparation. Similar results were obtained by the 2, 2-diphenyl-1-picrylhydrazyl free radical method.     

Ser71 of αS1‐Casein is Phosphorylated in Breast Milk—Evidence from Targeted Mass Analysis

Scope

The casein phosphoproteins in mother's milk supply calcium and phosphate ions and make them biologically available to the newborn. Human αS1‐casein is of particular interest being also an autoantigen and proinflammatory cytokine. Phosphorylation of αS1‐casein by casein kinase 2 completely abolishes binding to toll‐like receptor 4 and proinflammatory effects. It is, however, not known, which amino acids are affected. Therefore, breast milk samples were analyzed in an effort to detect the phosphorylation sites of αS1‐casein.

Methods and results

Breast milk samples were tryptically digested. Target tandem MS analysis confirmed the known phosphorylation sites S33 and S41; evidence for pS89 was found in some samples. Experimental support for the presence of pS31 and pS34 was weak. Phosphorylation of a new site in αS1‐casein, S71, was reproducibly measured in all samples, albeit at much lower intensity than pS33 and pS41.

Conclusion

Phospho‐occupancy rates varied greatly and could not be confidently correlated to other parameters within the cohort of 20 donors. The new phosphosite S71 is located in the neighborhood of the serine‐rich region and may contribute to the cluster of high charge density at normal milk pH, likely exerting an influence on protein tertiary structure and thus function.

     

高含水稀油油藏蒸汽驱过程中原油组成性质的变化

在大庆葡Ⅰ组非均质砂岩油藏的葡71-75井区进行了稀油(地下粘度4.9 mPa.s)蒸汽驱试验。试验区水驱采出程度22.62%,综合含水82.87%,包含1口注入井和分属不同井网的7口采油井。取3口典型采油井,测定注汽前、注汽78天和120天时采出原油组成、性质的变化。结果表明,在汽驱过程中采出原油的密度、凝固点、含蜡、含胶质沥青质及运动粘度下降;初馏点显著降低(120℃→84℃→75℃),总馏量和300℃前各馏分量增多;50~90℃动力粘度在汽驱120天时最低,汽驱78天时略高于汽驱前;气油比增大;全烃分析表明汽驱后采出油轻质馏分增多,成熟度提高。基于前人关于蒸汽驱中产生热水蒸馏混合带的见解,利用所得分析测试数据,讨论了稀油蒸汽驱油机理:初期以热膨胀为主,中期为热膨胀、蒸汽蒸馏和降粘,后期为蒸汽蒸馏。图5表3参6。     

也门69、71区块油气勘探前景展望

也门69、71区块为中原油田2004年通过选区评价在中东地区获得的新的油气勘探合同区块,它们分别位于也门境内富含油气的马里卜-夏布瓦盆地和塞云-马西拉盆地.初步的石油地质评价认为两区块内生、储、盖层及圈闭发育比较好,资源落实;区内钻井见良好油气显示,周边邻区均发现了规模较大的油气田或商业产层,因此两区块均具有较好的油气勘探前景.     

井间地震观测系统设计实例分析

垦71区块低序级断层组合关系不明、剩余油分布不清、油水关系复杂、储层较薄且多,纵、横向变化大。利用井间地震技术研究了该地区的低序级断层及储层特征。首先根据实施井间地震工区的地质模型建立速度模型,依据设计的观测系统进行正演模拟,模拟的波场反映了井间地震的主要波场特征,反射波成像剖面反映了地质模型的地质特征。基于正演模拟结果对观测系统进行优化,并进行野外采集,获得的实际资料的反射波成像剖面分辨率较高,落实了井间的低序级断层及薄储层。     

大斜度大位移井岩屑床的解决方法

在大斜度大位移高难度定向井中,岩屑易在井眼中形成岩屑床,导致蹩泵、蹩钻甚至卡钻。本文在分析岩屑床的形成及危害的基础上,对岩屑床的清除办法进行了探讨,提出了将提高泥浆返速、改善泥浆性能与机械清除岩屑相结合的方法。胜利油田多口井的现场应用表明,该方法能有效地解决高难度定向井的携岩问题,为优质高效的钻高难度定向井提供了一定的技术保证。     

NIR-II J-Aggregates Labelled Mesoporous Implant for Imaging-Guided Osteosynthesis with Minimal Invasion

Medical implants are widely used in clinical practice, such as cardiovascular stenting, maxillofacial surgery, and orthopedics. However, most of the traditional implant operations are open and invasive, resulting in massive dissection of soft tissue and interruption of blood supply. The accurate navigation for the implant operations is considered as one of the most effective ways to reduce the damage, which is urgently desired in clinic. Herein, a biocompatible NIR-II J-aggregates labelled mesoporous implant for imaging-guided osteosynthesis with minimal invasion is reported. Mesoporous silica layer with vertical channels is grown on the surface of titanium plate, which can provide the confining space for the formation of the FD-1080 J-aggregates. Both the absorption and fluorescence peaks of the FD-1080 J-aggregates are located in NIR-II window (beyond 1300 nm), which are ideal for high resolution and real time surgical navigation in deep tissue. NIR-II imaging can clearly display the location and outline of the implant both in vitro and in vivo. This NIR-II imaging-guided osteosynthesis can effectively reduce the surgical wound and operational duration, which is crucial for the implant surgeries.