鄂尔多斯盆地长73亚段深水重力流砂岩储层特征及控制因素——以华池地区CY1井为例

鄂尔多斯盆地延长组长7₃亚段泥页岩层系中发育的重力流成因的砂岩是长庆油田页岩油增储上产的潜在目标,但缺乏对长7₃亚段砂岩储层特征及页岩油富集控制因素的研究。基于华池地区CY1井长7₃亚段全取心井资料,利用X?射线衍射、扫描电镜、高压压汞及核磁共振等测试资料,结合薄片和岩心资料,深入分析了长7₃亚段砂岩储层的宏、微观特征,并对储集能力和含油性的控制因素进行了深入分析。结果表明：长7₃亚段主要发育灰色块状岩屑质长石、岩屑长石和长石岩屑粉砂岩,发育少量的细砂岩,属于典型的低孔低渗,储集层储集空间主要为粒间孔、长石溶孔、黏土矿物晶间孔、粒内溶孔和微裂缝,广泛发育的微纳米孔喉使其具有一定的储集能力;长7₃亚段微观孔隙结构主要分为A、B、C 3类,孔喉半径中值和微观孔喉分选系数是控制饱和度中值压力、最大进汞饱和度和退汞效率的主要参数,影响了微观尺度上页岩油的富集程度和渗流能力;长7₃亚段砂岩的矿物组成、粒度、微观孔隙结构共同控制着长7₃亚段砂质岩的储集能力,生烃增压促使长7₃亚段黑色页岩中的轻质烃向着与其相临的渗流能力较好的砂岩聚集,粒间孔、长石溶蚀孔及微裂缝是游离烃的主要储集空间,黏土矿物是吸附烃的主要赋存空间,在长7₃亚段泥页岩层系中寻找长英质矿物含量高、黏土矿物含量少、方解石胶结作用弱的砂岩是页岩油勘探开发的主要目标;以A、B类孔隙结构为代表的孔隙度大于5%、渗透率高于0.05×10^-3 μm²的砂岩是长7₃亚段优势储集层,C类孔隙结构代表的砂岩油气充注难度大,物性及渗流能力差,不利于页岩油的聚集和采出。     

基于磁感传感器SEN-S的电子指南针系统

本文详细地阐述了磁感传感器SEN-SL以及其驱动芯片PNI11096的使用方法.简要地介绍了确定方向的基本原理,同时给出了指南针系统的硬件设计原理图以及系统软件设计的流程图.     

7A09CT73铝合金挤压型材热处理工艺研究

系统地讨论了7A09CT73铝合金挤压型材的热处理工艺,特别是二阶段时效工艺对7A09CT73型材组织性能的影响,初步确定了7A09CT73型材热处理工艺、组织、性能三者的关系。     

Multiplex qualitative PCR assay for identification of genetically modified canola events and real-time event-specific PCR assay for quantification of the GT73 canola event

Genetically modified (GM) canola is the most widely grown oilseed crop in Canada. At this time, commercially produced GM canola cultivars in Canada have the events GT73/RT73 and Ms8xRf3. Commercial seed sale of canola cultivars containing the GM events such as OXY235 and T45 has been discontinued. Adventitious presence of GM seeds and grains in non-GM grains is a concern for international grain trade, and development of effective detection methods is important. A multiplex qualitative PCR procedure was established for the detection of the GM canola events OXY235, Ms8xRf3, T45 and GT73. The presence of the GM canola events was also successfully detected in ground spiked wheat and barley grain samples prepared at 0.1%, 0.5% and 1.0% levels (w/w). The GT73 real-time PCR assay was successfully used to quantify DNA extracted from spiked ground canola samples consisting of 5%, 1%, 0.5% and 0.1% GT73 (w/w).     

Baupolizeiliche Ma?nahmen; Vertrauensschutz

Eine in Aussicht gestellte ?nderung des Fl?chenwidmungsplanes zur Sanierung rechtswidriger Bauten steht baupolizeilichen Ma?nahmen nicht entgegen.     

Inducing transformational energy technological change

Reducing risks of severe climate change in the latter part of the 20th Century is likely to require not only incremental improvements in known energy technologies, but the discovery of transformational new energy technologies. This paper reviews current knowledge about both demand and supply aspects of the challenge of accelerating transformational change, considering both economic and policy incentives, including targeted government funding of research and development, and several other schools of thought about drivers of scientific discovery and innovation.     

The Inhibition of the Inducible Nitric Oxide Synthase Enhances the DPSC Mineralization under LPS-Induced Inflammation

Nitric oxide (NO) is a key messenger in physiological and pathological processes in mammals. An excessive NO production is associated with pathological conditions underlying the inflammation response as a trigger. Among others, dental pulp inflammation results from the invasion of dentin by pathogenic bacteria. Vital functions of pulp mesenchymal stem cells (DPSCs, dental pulp stem cells), such as mineralization, might be affected by the inducible NOS (iNOS) upregulation. In this context, the iNOS selective inhibition can be considered an innovative therapeutic strategy to counteract inflammation and to promote the regeneration of the dentin-pulp complex. The present work aims at evaluating two acetamidines structurally related to the selective iNOS inhibitor 1400W, namely CM544 and FAB1020, in a model of LPS-stimulated primary DPSCs. Our data reveal that CM544 and even more FAB1020 are promising anti-inflammatory compounds, decreasing IL-6 secretion by enhancing CD73 expression-levels, a protein involved in innate immunity processes and thus confirming an immunomodulatory role of DPSCs. In parallel, cell mineralization potential is retained in the presence of compounds as well as VEGF secretion, and thus their angiogenetic potential. Data presented lay the ground for further investigation on the anti-inflammatory potential of acetamidines selectively targeting iNOS in a clinical context.     

E as in Enigma: The Mysterious Role of the Voltage-Dependent Anion Channel Glutamate E73

The voltage-dependent anion channel (VDAC) is the main passageway for ions and metabolites over the outer mitochondrial membrane. It was associated with many physiological processes, including apoptosis and modulation of intracellular Ca²⁺ signaling. The protein is formed by a barrel of 19 beta-sheets with an N-terminal helix lining the inner pore. Despite its large diameter, the channel can change its selectivity for ions and metabolites based on its open state to regulate transport into and out of mitochondria. VDAC was shown to be regulated by a variety of cellular factors and molecular partners including proteins, lipids and ions. Although the physiological importance of many of these modulatory effects are well described, the binding sites for molecular partners are still largely unknown. The highly symmetrical and sleek structure of the channel makes predictions of functional moieties difficult. However, one residue repeatedly sticks out when reviewing VDAC literature. A glutamate at position 73 (E73) located on the outside of the channel facing the hydrophobic membrane environment was repeatedly proposed to be involved in channel regulation on multiple levels. Here, we review the distinct hypothesized roles of E73 and summarize the open questions around this mysterious residue.