Solving a multi-floor layout design model of a dynamic cellular manufacturing system by an efficient genetic algorithm

This paper presents a mixed-integer programming model for a multi-floor layout design of cellular manufacturing systems (CMSs) in a dynamic environment. A novel aspect of this model is to concurrently determine the cell formation (CF) and group layout (GL) as the interrelated decisions involved in the design of a CMS in order to achieve an optimal (or near-optimal) design solution for a multi-floor factory in a multi-period planning horizon. Other design aspects are to design a multi-floor layout to form cells in different floors, a multi-rows layout of equal area facilities in each cell, flexible reconfigurations of cells during successive periods, distance-based material handling cost, and machine depot keeping idle machines. This model incorporates with an extensive coverage of important manufacturing features used in the design of CMSs. The objective is to minimize the total costs of intra-cell, inter-cell, and inter-floor material handling, purchasing machines, machine processing, machine overhead, and machine relocation. Two numerical examples are solved by the CPLEX software to verify the performance of the presented model and illustrate the model features. Since this model belongs to NP-hard class, an efficient genetic algorithm (GA) with a matrix-based chromosome structure is proposed to derive near-optimal solutions. To verify its computational efficiency in comparison to the CPLEX software, several test problems with different sizes and settings are implemented. The efficiency of the proposed GA in terms of the objective function value and computational time is proved by the obtained results.     

输血后丙型肝炎病毒NS4区抗体的动态变化及其诊断意义

利用重组NS4抗原及合成肽5－11抗原分别检测5例输血后丙型肝炎患者的系列血清136份，并与HCV总抗体及HCVRNA检测结果比较，发现抗NS4抗体的动态变化虽然有两种模式，但在多数情况下为一种模式，即抗体阳转后很少转阴，并且其动态变化基本与总抗体相似。同时发现2例病人抗NS4抗体阳转时间早于总抗体，因此，推测HCV检测试剂中增加NS4抗原可能对提高HCV诊断试剂的灵敏度有一定意义。     

Esterification of acrylic acid with methanol by reactive chromatography: Experiments and simulations

The esterification of acrylic acid with methanol using Amberlyst 15 as a stationary phase has been investigated using a chromatographic reactor. Several experimental runs at various operating conditions have been conducted on a batch column. A classical reactive chromatography model including lumped kinetics, a linear driving force transport model and a heterogeneous kinetic model for the catalytic reaction has been developed. The additional dispersion of concentration fronts due to density gradient effects has been accounted for in the model. The model parameters have been determined in a fast and reliable way by directly fitting the batch column experiments. In general, a good agreement between experimental and calculated results is obtained. The evaluation of the covariance of the fitted model parameters reveals important insights about the system behavior.Based on the detailed batch column model, a complete model of a simulated-moving-bed reactor has been implemented and its optimal point of operation for the synthesis of methyl acrylate from acrylic acid has been determined. Particularly when considering the low-operating temperature, we can regard this process as a possible competition for current technologies.     

Consistent hierarchical economic NMPC for a class of hybrid systems using neighboring-extremal updates

A hierarchical two-layer control algorithm is developed for a class of hybrid (discrete-continuous dynamic) systems to support economically optimal operation of batch or continuous processes with a predefined production schedule. For this class of hybrid systems, the optimal control moves as well as the controlled switching times between two adjacent modes are determined online. In contrast to closely related schemes for integrated scheduling and control, the sequence of modes is not optimized. On the upper layer, the economic optimal control problem is solved rigorously by a slow hybrid economic model predictive controller at a low sampling rate. On the lower layer, a fast hybrid neighboring-extremal controller is based on the same economic optimal control problem as the slow controller to ensure consistency between both layers. The fast neighboring-extremal controller updates rather than tracks the optimal trajectories from the upper layer to account for disturbances. Consequently, the fast controller steers the process to its operational bounds under disturbances and the economic potential of the process is exploited anytime. The suggested two-layer control algorithm provides fully consistent control action on the fast and slow time-scale and thus avoids performance degradation and even infeasibilities which are commonly encountered if inconsistent optimal control problems are formulated and solved.     

新型偶联剂对橡胶力学性能的影响

本文讨论了新型偶联剂用量对陶土填充橡胶与炭黑填充橡胶动态性能与力学性能的影响．并且用红外光谱对偶联剂改性陶土表面进行了表征。结果表明：该偶联剂明显提高硫化胶的动态性能、撕裂强度及陶土填充橡胶的拉伸强度，其用量超过１．５重量份对硫化胶的力学性能有不良影响。     

Catching a molecule at the air-water interface: Dynamic pore array for molecular recognition

As a soft and flexible porous structure, a pore array of a steroid cyclophane SC(OH), which consists of the rigid 1,6,20,25-tetraaza[6.1.6.1]paracyclophane ring connected to four steroid moieties (cholic acid) through flexible L-lysine spacers, was prepared at the air-water interface. As confirmed by surface pressure (π)-molecular area (A) isotherms, transition between open conformation and cavity conformation of the SC(OH) molecule was reversibly induced upon repeated compression and expansion of its monolayer at pH 11 where amino groups of the lysine residues are not fully deprotonated. Capture and release of an aqueous fluorescent guest (TNS) by SC(OH) was observed upon dynamic cavity formation through surface fluorescence spectroscopy. At pH 12, dynamic cavity formation of SC(OH) was sufficiently suppressed, and the capture and release of an aqueous TNS by the monolayer was not virtually observed. Lessened electrostatic repulsion between the SC(OH) molecules due to conversion of ammonium to free amine may prevent the cavity from reopening. The importance of dynamic nature of cavity formation on the guest binding was also proved by control experiments using SC(H), which cannot form cavity conformation at any surface pressures at both pH 11 and 12.     

基于BACnet/IP的设备与实时数据库通信实现

针对不同厂商、不同系统的楼宇自控设备互操作、互通信的局限性,分析了BACnet/IP技术和实时数据库,设计开发了一种基于BACnet/IP技术的实时数据库DasRdb的设备驱动程序。该设备驱动程序采用UDP通信方式,通过调用每个BACnet/IP设备的标准接口函数来驱动实时数据库DasRdb分别进行写操作和读操作,能够有效地实现BACnet/IP设备与实时数据库DasRdb之间的通信,从而使楼控设备的互操作成为可能。现场工程应用表明,该程序的运行契合BACnet的一致性要求,具有简单、高效、精确度高、实时性好的特点。     

Size segregation in gas-solid fluidized beds with continuous size distributions

Discrete-particle simulations of a gas-solid fluidized bed are used to investigate the species segregation (de-mixing) behavior of systems with continuous particle size distributions. Both Gaussian and lognormal distributions are investigated over a range of distribution widths, restitution and friction coefficients, and gas velocities. The results indicate that: (i) the average particle diameter decreases as the height within the bed increases, (ii) the level of segregation increases with an increase in the width of the particle size distribution, and (iii) segregation is attenuated as bubbling becomes more vigorous. Furthermore, the shape of the local size distribution (i.e., Gaussian or lognormal) is found to mimic that of the overall size distribution in most regions of the fluidized bed.     

复合胺改性尼龙6的动态流变性能研究

在己内酰胺水解聚合时加入一定量的复合受阻胺，合成出含有复合胺的改性尼龙6树脂，研究了复合胺对尼龙6熔体的动态流变性能的影响。实验表明：随着剪切频率的增加，尼龙6熔体的复数粘度减小、储能模量和损耗模量均增大；但由于复合胺的加入，在尼龙6大分子链上引入了空间位阻基团，复合胺改性尼龙6熔体的复数粘度、储能模量及损耗模量均比未改性样增大；改性前后尼龙6的损耗因子均随剪切频率的增加呈现先增加后减小的变化趋势，在频率为18 rad／s的位置出现极大值——内耗峰，但改性尼龙6的峰值更大；改性前后尼龙熔体的lgG′～lgG″曲线均在对角线右下方，随复合胺的加入，曲线向右下方位移增大，熔体的粘性响应更明显。     

聚苯硫醚／聚砜共混物的动态黏弹行为及相容性研究

研究了聚苯硫醚／聚砜熔融共混物的的加工流变行为以及共混物在不同温度下的动态黏弹响应；并对其相容性作出判断。结果表明，聚苯硫醚的加入显著改善了共混物的流动性，使其可在较低温度下成型；熔融态共混体系的相容性较差，固态条件下的相分离程度及损耗因子峰值大小依赖于组成变化。