融合注意力线性特征多样化的DR分级模型

糖尿病视网膜病变(diabetic retinopathy, DR)是目前人类的主要致盲疾病之一。针对DR数据集中样本类间差异小和类分布不均衡等制约分级性能提高的问题,本文提出一种融合注意力线性特征多样化(fusion of attention linear feature diversification, FALFD)的分级算法。该算法首先用改进的Res2Net残差网络作为模型骨干来增大感受野,进一步提高网络捕捉特征信息的能力;其次引入自适应特征多样化模块(adaptive feature diversification module, AFDM)对眼底图像可分辨的微小病理特征进行识别,获得具有高语义信息的局部特征,避免单一特征区域的限制,进而提高分级准确度;再后利用双线性注意力融合模块(bilinear attention fusion module, BAFM)增加可判别区域特征的网络权重占比;最后采用正则化焦点损失(focal loss, FL)进一步提升算法的分类性能。在IDRID数据集上,灵敏度和特异性分别为94.20%和97.05%,二次加权系数为87.83%;在APTO...     

一种新型的无人机牧草分割网络—LMS-DeeplabV3+

目前草原环境复杂、牧草分散且与背景颜色差异小,无法实现高效精准的分割,因此本文提出了一种新型的轻量化多尺度DeeplabV3+网络(lightweight and multi-scale DeeplabV3+network, LMS-DeeplabV3+)。该网络以DeeplabV3+为基础网络,首先选用轻量级的MobilenetV2作为骨干网络用于初步特征提取,并为了适应牧草分割任务做了网络配置上的调整;其次在加强特征提取模块和解码模块中均使用深度可分离卷积代替普通卷积以轻量化网络;此外利用密集空洞空间金字塔池化(dense atrous spatial pyramid pooling, DASPP)模块捕获更大的感受野,加强各特征之间的交互;又引入卷积注意力机制(convolutional block attention module, CBAM)重分配权重加强特征提取。实验证明,提出的新网络与原始网络相比平均交并比(mean intersection over union,mIOU)提升了8.06个百分点、平均像素精度(mean pixel accuracy,mPA)提升了6.7...     

Proteomic Biomarkers of the Apnea Hypopnea Index and Obstructive Sleep Apnea: Insights into the Pathophysiology of Presence,Severity, and Treatment Response

Obstructive sleep apnea (OSA), a disease associated with excessive sleepiness and increased cardiovascular risk, affects an estimated 1 billion people worldwide. The present study examined proteomic biomarkers indicative of presence, severity, and treatment response in OSA. Participants (n = 1391) of the Stanford Technology Analytics and Genomics in Sleep study had blood collected and completed an overnight polysomnography for scoring the apnea–hypopnea index (AHI). A highly multiplexed aptamer-based array (SomaScan) was used to quantify 5000 proteins in all plasma samples. Two separate intervention-based cohorts with sleep apnea (n = 41) provided samples pre- and post-continuous/positive airway pressure (CPAP/PAP). Multivariate analyses identified 84 proteins (47 positively, 37 negatively) associated with AHI after correction for multiple testing. Of the top 15 features from a machine learning classifier for AHI ≥ 15 vs. AHI < 15 (Area Under the Curve (AUC) = 0.74), 8 were significant markers of both AHI and OSA from multivariate analyses. Exploration of pre- and post-intervention analysis identified 5 of the 84 proteins to be significantly decreased following CPAP/PAP treatment, with pathways involving endothelial function, blood coagulation, and inflammatory response. The present study identified PAI-1, tPA, and sE-Selectin as key biomarkers and suggests that endothelial dysfunction and increased coagulopathy are important consequences of OSA, which may explain the association with cardiovascular disease and stroke.     

网络环境下新产品开发知识团队研究综述*

在综述国内外学者有关新产品开发知识团队研究成果的基础上,试图梳理出现阶段该领域的研究热点与难点问题,为后续研究奠定一定的理论基础。分别从团队的定义和类型,团队学习与团队管理,新产品开发知识团队的概念、类型、运作与管理等方面对已有的研究文献进行了系统的综述,在此基础上提出了已有研究的局限性及对未来研究的展望。     

Learning Structure from Data and Its Application to Ozone Prediction

In this paper we propose an algorithm for structure learning in predictive expert systems based on a probabilistic network representation. The idea is to have the simplest structure (minimum number of links) with acceptable predictive capability. The algorithm starts by building a tree structure based on measuring mutual information between pairs of variables, and then it adds links as necessary to obtain certain predictive performance. We have applied this method for ozone prediction in México City, where the ozone level is used as a global indicator for the air quality in different parts of the city. It is important to predict the ozone level a day, or at least several hours in advance, to reduce the health hazards and industrial losses that occur when the ozone reaches emergency levels. We obtained as a first approximation a tree-structured dependency model for predicting ozone in one part of the city. We observe that even with only three parameters, its estimations are acceptable.A causal network representation and the structure learning techniques produced some very interesting results for the ozone prediction problem. Firstly, we got some insight into the dependence structure of the phenomena. Secondly, we got an indication of which are the important and not so important variables for ozone forecasting. Taking this into account, the measurement and computational costs for ozone prediction could be reduced. And thirdly, we have obtained satisfactory short term ozone predictions based on a small set of the most important parameters.     

Warning: statistical benchmarking is addictive. Kicking the habit in machine learning

Algorithm performance evaluation is so entrenched in the machine learning community that one could call it an addiction. Like most addictions, it is harmful and very difficult to give up. It is harmful because it has serious limitations. Yet, we have great faith in practicing it in a ritualistic manner: we follow a fixed set of rules telling us the measure, the data sets and the statistical test to use. When we read a paper, even as reviewers, we are not sufficiently critical of results that follow these rules. Here, we will debate what are the limitations and how to best address them. This article may not cure the addiction but hopefully it will be a good first step along that road.     

基于极端学习机的MANET移动性预测模型

针对移动自组织网络移动性在管理无线网络带宽资源可用性方面的重要性,为了更好地规划连续服务可用性和有效能源管理以提升网络的整体服务质量,提出了一种基于极端学习机的MANET移动性预测模型。利用ELM对MANET中的任意节点进行建模;假设已知每个移动节点当前的移动性信息（位置、速度和运动方向角度）,以这种方式预测节点未来的位置和相邻节点之间未来的距离;基于几个标准移动性模型,产生更加真实、精确的移动性预测,从而更好地捕捉任意节点直角坐标系之间现有交互/相关性。使用标准移动性模型的仿真结果验证了所提模型的有效性,实验结果表明,提出的预测模型明显改进了传统基于多层感知器的模型,此外,当预测相邻节点之间未来距离时,避免了当前算法对预测精度的限制。     

灰色偏相关评价法在认知型学生模型中的应用

针对认知能力评价这类因素较多,且难以进行定量描述的问题,建立认知能力因素评价体系,利用灰色偏相关评价法建立认知型学生模型。首先分析各认知能力因素的相互影响关系,计算偏相关系数得到各认知能力因素的权重值。然后确定评价灰类,建立白化权函数,得到各认知能力因素关于各评价灰类的灰色评价权值,从而建立认知型学生综合评价模型。最后通过实例对方法模型进行验证。实例表明,该方法模型能够对学生知识水平作出评价并引导学生进行学习,其结果具有一定的可靠性。     

多概念层次上基于赋范划分距离的分类算法

应用知识发现理论与方法从大型考生信息数据库中提取隐含的、前所未知的、对决策有潜在价值的知识和规则,是当前计算机教育应用的新课题。根据网上远程考试与评价系统的特点,讨论了挖掘的目标规则类型及其挖掘算法。针对ID3算法的不足,提出了一种新的分类算法－多概念层次上基于赋范划分距离的分类算法,简要介绍了XML在知识发现过程中的应用。     

支持向量机的新发展

Vapnik等学者首先提出了实现统计学习理论中结构风险最小化原则的实用算法一支持向量机，比较成功地解决了模式分类问题，其后，机器学习界兴起了研究统计学习理论和支持向量机的热湖，引人瞩目的研究分支有从最优化技术出发改进或改造支持向量机，依据统计学习理论和支持向量机的优点设计新的非线性机器学习算法等，对此，较为系统地回顾了近lO年来算法研究领域的新发展。