Toxicoproteomics and its application to human health risk assessment

Toxicoproteomics is the use of proteomic technologies to better understand environmental and genetic factors, toxic mechanisms, and modes of action in response to acute exposure to toxicants and in the long-term development of diseases caused or influenced by these exposures. Use of toxicoproteomic technologies to identify key biochemical pathways, mechanisms, and biomarkers of exposure and toxicity will decrease the uncertainties that are associated with human health risk assessments. This review provides an overview of toxicoproteomics from human health risk assessment perspectives. Key toxicoproteomic technologies such as 2-D gel-based proteomic methods and toxicoproteomic approaches are described, and examples of applications of these technologies and methodologies in the risk assessment context are presented. The discussion includes a focus on challenges and future directions.     

知识网格中基于RDF的知识表示技术和应用

简要介绍了两种基本的知识表示技术,以及各自的优缺点;详细介绍了RDF技术,提出了一种基于RDF的知识表示技术及其形式、语法和语义;以数字图书馆信息资源描述的一个实例说明了该技术的实际应用。     

一种基于RBAC的Web环境下信息系统权限控制方法

信息系统的权限管理是保证数据安全的必要条件。在论述了基于角色的权限控制模型的基础上,分析了基于用户-功能的权限控制方法存在的问题,提出了一种基于RBAC的B/S体系结构的信息系统权限控制方法,实现了安全的权限控制,取得了较好的效果。     

经管类专业应用型人才培养模式研究

民办高校应用型人才培养模式是民办高校为培养应用型人才而探索形成的一种可操作性的经验与理论架构。本文简单阐述了经管类专业应用型人才培养的意义,构建了经管类专业应用型人才培养方案,主要是构建以企业为依托的合作办学模式,构建＂两平台＋N模块＋一拓展＂课程体系,构建以学生为主体的教学方法和＂双师型＂师资队伍。     

手机广告模式与计费方式探讨

随着手机的普及和移动互联网的发展,手机具备了巨大的广告价值潜力。我国的手机广告产业发展处于初期阶段,手机平台巨大的广告潜力尚未得到充分认识和合理利用。本文将以手机广告市场的宏观现状、趋势和广告行情为基础,对中国手机广告产业的商业模式和计费方式进行探讨。     

构建鄱阳湖生态经济区低碳农业发展的路径思考

在全球气候变暖的条件下,发展低碳农业已成为不可逆转的趋势。鄱阳湖生态经济区内农业碳资源比较丰富,且极具开发潜力,因此,低碳农业发展空间巨大。鄱阳湖生态经济区内各地政府要立足当地资源优势,充分挖掘当地农业碳资源,通过发展有机农业和循环农业,加大植树造林力度,加强湿地保护,促使农业由高碳向低碳有效转变。     

Impact of speech presentation level on cognitive task performance: implications for auditory display design

Speech displays and verbal response technologies are increasingly being used in complex, high workload environments that require the simultaneous performance of visual and manual tasks. Examples of such environments include the flight decks of modern aircraft, advanced transport telematics systems providing in-vehicle route guidance and navigational information and mobile communication equipment in emergency and public safety vehicles. Previous research has established an optimum range for speech intelligibility. However, the potential for variations in presentation levels within this range to affect attentional resources and cognitive processing of speech material has not been examined previously. Results of the current experimental investigation demonstrate that as presentation level increases within this ‘optimum’ range, participants in high workload situations make fewer sentence-processing errors and generally respond faster. Processing errors were more sensitive to changes in presentation level than were measures of reaction time. Implications of these findings are discussed in terms of their application for the design of speech communications displays in complex multi-task environments.     

以“卓越工程师”为导向的通信专业具有创新精神的人才培养模式研究与实践

本文系统地介绍了通信专业以“卓越工程师”为导向的具有创新精神的人才培养模式的人才培养目标的制定、课程体系的构建、创新型教学团队、渐进式创新意识和创新能力培养等内容,以期培养更多优秀的工程技术人才。     

经验模态分解效果与信号频率振幅的关系

利用经验模态分解(Empirical Mode Decomposition,简称EMD)方法对由两个正弦线性叠加而成的信号进行分离处理,研究正弦信号的频率和振幅对EMD分离效果的影响.通过多组实验得出,两正弦信号的频率相差越大或振幅相差越小,EMD分离效果越明显.     

产学模式在《数据库原理》课程教学改革中的应用

针对目前《数据库原理》课程采用传统教学模式存在的诸多问题,就如何提高应用型本科计算机专业学生对《数据库原理》课程的学习兴趣和解决实际问题的能力,提出了产学相结合的数据库原理课程教学模式,首先让学生在工程化环境中进行相关理论学习,同时提供课程网站等辅助手段进行扩展学习,在此基础上根据企业的实际需求模拟环境让学生进行实践,并对其实践展开了进一步讨论。