Reasoning about non-immediate triggers in biological networks

Modeling molecular interactions in signalling networks is important from various perspectives such as predicting side effects of drugs, explaining unusual cellular behavior and drug and therapy design. Various formal languages have been proposed for representing and reasoning about molecular interactions. The interactions are modeled as triggered events in most of the approaches. The triggering of events is assumed to be immediate: once an interaction is triggered, it should occur immediately. Although working well for engineering systems, this assumption poses a serious problem in modeling biological systems. Our knowledge about biological systems is inherently incomplete, thus molecular interactions are constantly elaborated and refined at different granularity of abstraction. The model of immediate triggers can not consistently deal with this refinement. In this paper we propose an action language to address this problem. We show that the language allows for refinements of biological knowledge, although at a higher cost in terms of complexity.      

基于GRNN网络模型的土壤重金属空间分布的研究

以江苏省南通市为研究区,利用采样点实测数据,借助GRNN神经网络模型并结合3S技术对农田土壤重金属的空间动态分布进行了深入研究。结果表明,GRNN神经网络模型能够智能地学习各个采样点的空间位置与该点各重金属含量之间的映射关系,并能够稳健地对各个空间插值点处的土壤重金属含量进行预测;结果显示南通市农田土壤重金属污染总体较轻,但也存在局部地区的严重污染。在运用GRNN神经网络模型进行空间插值了解重金属空间动态分布的基础上,可以根据污染的状况确定农产品的生产布局和规划。     

Impacts of spectral band difference effects on radiometric cross-calibration between satellite sensors in the solar-reflective spectral domain

In order for quantitative applications to make full use of the ever-increasing number of Earth observation satellite systems, data from the various imaging sensors involved must be on a consistent radiometric scale. This paper reports on an investigation of radiometric calibration errors due to differences in spectral response functions between satellite sensors when attempting cross-calibration based on near-simultaneous imaging of common ground targets in analogous spectral bands, a commonly used post-launch calibration methodology. Twenty Earth observation imaging sensors (including coarser and higher spatial resolution sensors) were considered, using the Landsat solar reflective spectral domain as a framework. Scene content was simulated using spectra for four ground target types (Railroad Valley Playa, snow, sand and rangeland), together with various combinations of atmospheric states and illumination geometries. Results were obtained as a function of ground target type, satellite sensor comparison, spectral region, and scene content. Overall, if spectral band difference effects (SBDEs) are not taken into account, the Railroad Valley Playa site is a “good” ground target for cross calibration between most but not all satellite sensors in most but not all spectral regions investigated. “Good” is defined as SBDEs within ± 3%. The other three ground target types considered (snow, sand and rangeland) proved to be more sensitive to uncorrected SBDEs than the RVPN site overall. The spectral characteristics of the scene content (solar irradiance, surface reflectance and atmosphere) are examined in detail to clarify why spectral difference effects arise and why they can be significant when comparing different imaging sensor systems. Atmospheric gas absorption features are identified as being the main source of spectral variability in most spectral regions. The paper concludes with recommendations on spectral data and tools that would facilitate cross-calibration between multiple satellite sensors.     

A Macro Model of Frequently Changing Mobile Networks to Perform Flow and Access Control

The area covered by a mobile ad hoc network consists of obstacles that inhibit transmission and areas where communications can take place. Physical structures, such as buildings, that block transmission, or lakes, where forwarding nodes cannot be located, are permanent obstacles. Temporary obstacles are created as mobile nodes enter or leave an area. Our hypothesis is that the spaces between nearby obstacles are bottlenecks that inhibit the flows in the network. We partition the network into areas that are encompassed by obstacles and bottlenecks. All of the nodes in an area are treated as a single super node, and the bottlenecks between areas are the links between the super nodes. As individual nodes move, the flows and paths in the model change more slowly than the paths and flows between the individual nodes. We apply flow control algorithms to the model and perform admission control within a super node based on the flows that are assigned by the flow control algorithm. We apply the model to the Columbia University campus, and use max–min, fair bottleneck flow control to assign the flows. Our hypothesis is verified for this example.     

Networks for sorting multitonic sequences

Lee and Batcher have designed networks that efficiently merge k separately provided sorted sequences of known lengths totalling n. We show that the design is still possible, and in fact easier to describe, if we do not make use of the lengths, or even the directions of monotonicity, of the individual sequences—the sequences can be provided in a single undelimited concatenation of length n. The depth of the simplest resulting network to sort sequences that are “k-tonic” and of length n is , generalizing Batcher's 1968 results for the extreme values of k (k=2 corresponding to merging, and k=n/2 corresponding to general sorting).The exposition is self-contained and can serve even as an introduction to sorting networks and Batcher's results.     

Nonlinear black-box modeling in system identification: a unified overview

A nonlinear black-box structure for a dynamical system is a model structure that is prepared to describe virtually any nonlinear dynamics. There has been considerable recent interest in this area, with structures based on neural networks, radial basis networks, wavelet networks and hinging hyperplanes, as well as wavelet-transform-based methods and models based on fuzzy sets and fuzzy rules. This paper describes all these approaches in a common framework, from a user's perspective. It focuses on what are the common features in the different approaches, the choices that have to be made and what considerations are relevant for a successful system-identification application of these techniques. It is pointed out that the nonlinear structures can be seen as a concatenation of a mapping form observed data to a regression vector and a nonlinear mapping from the regressor space to the output space. These mappings are discussed separately. The latter mapping is usually formed as a basis function expansion. The basis functions are typically formed from one simple scalar function, which is modified in terms of scale and location. The expansion from the scalar argument to the regressor space is achieved by a radial- or a ridge-type approach. Basic techniques for estimating the parameters in the structures are criterion minimization, as well as two-step procedures, where first the relevant basis functions are determined, using data, and then a linear least-squares step to determine the coordinates of the function approximation. A particular problem is to deal with the large number of potentially necessary parameters. This is handled by making the number of ‘used’ parameters considerably less than the number of ‘offered’ parameters, by regularization, shrinking, pruning or regressor selection.     

A real-time planning algorithm for obstacle avoidance of redundant robots

A computationally efficient, obstacle avoidance algorithm for redundant robots is presented in this paper. This algorithm incorporates the neural networks and pseudodistance function D _p in the framework of resolved motion rate control. Thus, it is well suited for real-time implementation. Robot arm kinematic control is carried out by the Hopfield network. The connection weights of the network can be determined from the current value of Jacobian matrix at each sampling time, and joint velocity commands can be generated from the outputs of the network. The obstacle avoidance task is achieved by formulating the performance criterion as D _p>d _min (d _min represents the minimal distance between the redundant robot and obstacles). Its calculation is only related to some vertices which are used to model the robot and obstacles, and the computational times are nearly linear in the total number of vertices. Several simulation cases for a four-link planar manipulator are given to prove that the proposed collision-free trajectory planning scheme is efficient and practical.     

掺镉纳米SnO2的热稳定性,电导及气敏性能

本文研究了ＣｄＯ掺杂对纳米ＳｎＯ２粉料的热稳定性，电导及气敏特性的影响。结果表明，以非晶状态均匀分散在ＳｎＯ２颗粒表面的ＣｄＯ能阻止ＳｎＯ２之间的相互扩散，提高了纳米ＳｎＯ２的热稳定性；固溶于ＳｎＯ２昌粒中的ＣｄＯ量（Ｃｄ／Ｓｎ〈０．０５）很小，但对元件的电导影响显著；纳米级的晶粒尺寸（〈６ｎｍ）及ＣｄＯ的掺杂大大改善了ＳｎＯ２的气敏特性。     

基于自组织神经网络的实时统计特征抽取方法

应用人工神经网络讨论统计了特征抽取的原理，提出了相应的抽取方法。该方法具有实时性，容错性，高数据压缩率和良好的特征分辨率。通过计算机仿真和桥梁索力状态的实例计算分析证实了该技术具有广泛的应用价值。     

国外战场雷达发展现状

本文介绍国外战场雷达的现状,包括轻小型化、武器定位及低空目标探测等几个方面。