硼中子俘获治疗

硼中子俘获治疗(BNCT)的基本原理是应用热中子照射靶向聚集在肿瘤部位的^10B，^10B俘获中子后产生α粒子和^7Li，α粒子和^7Li杀灭肿瘤细胞而起到治疗作用。BNCT在临床上主要用于神经胶质瘤和黑色素瘤的治疗。文章主要对有关BNCT的基础及临床研究进行了简要综述，内容包括BNCT的基本原理、^10B在肿瘤细胞的聚集、中子源、实验研究现状以及BNCT面临的挑战与问题等。     

狗急性铀中毒和用Tiron急救治疗

本文报道了狗的急性铀中毒和用 Tiron 进行急救治疗的实验结果。观察指标包括尿铀排除率、主要的临床生物化学指标、病理组织学以及病程经过。结果表明,Tiron 或 Tiron 与碳酸氢钠伍用,显示较好的急救治疗效果。     

钴疗机漏射线照射量率的空间分布

本文简要介绍了对五种型号钴疗机在“开”位时机头漏射线照射量率 X_(γ,θ,ψ)空间分布的测量结果,并给出了估算 X_(γ,θ,ψ)的经验公式,可为钴疗机房屏蔽设计和辐射防护监督提供参考。     

老年急性髓细胞白血病的临床、生物学特征及治疗进展

急性髓细胞白血病(AML)的诸多预后不良因素中,年龄≥60岁是一个重要的不良预后指标.原因除了与老年患者本身的生理特点有关,更重要的是由于其白血病细胞的生物学特征与青年患者显著不同.现就老年AML患者的临床、生物学特征及在此基础上的治疗进展进行综述.     

核酶抗病毒基因治疗的研究进展

核酶的发现突破了蛋白酶类传统生物催化剂的概念,由于它能特异性结合并切割病毒RNA,而又不影响宿主细胞RNA,因而在抗病毒的基因治疗研究中具有潜在的应用价值。     

Structural Ecosystems Therapy for HIV-Seropositive African American Women: Effects on Psychological Distress, Family Hassles, and Family Support.

This study tests the efficacy of Structural Ecosystems Therapy (SET), a family-ecological intervention, in improving psychosocial functioning when compared with an attention-comparison person-centered condition and a community control condition. A sample of 209 HIV-seropositive, urban, low-income, African American women was randomized into 1 of the 3 conditions. Results of growth curve analyses over 5 time points revealed that SET was more efficacious than either of the control conditions in reducing psychological distress and family-related hassles. However, contrary to hypotheses, SET was not more efficacious in increasing family support. Latent growth mixture modeling analyses indicated that SET was most efficacious for women who, on average, were at or near the clinical threshold for psychological distress and for women with high levels of family hassles. Implications for further intervention development are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

一种神经康复机器人的研制

介绍了一种神经康复机器人,阐述了机器人的详细结构、工作原理、使用方法以及在结构上和控制模式上为 了保证患者瘫肢的安全所采取的策略。通过健康人实验证实了该机器人能够满足神经损伤患者康复训练的一般要 求,有望用于患者的临床康复训练。     

Effect of α-Tocopherol During In Vitro Ozonation of Methyl Linoleate: Its Implication in Ozone Therapy

Systemic ozone therapy is widely used as an oxidant therapy to treat many conditions and diseases. It is known that ozone therapy acts through a transient oxidative stress produced by lipid ozonation products. The convenience of supporting patients with antioxidants during systemic ozone therapy applications is now under discussion. We studied the reaction of linoleate (one of the main constituents of cellular membranes and plasma phospholipids) with ozone in presence or absence of α-tocopherol, in order to explore whether the combination of ozone and antioxidant has some effect on fatty acid ozonation products. Proton nuclear magnetic resonance spectroscopy (¹H NMR) was used for following the reaction between 4.8mol mmol of methyl linoleate and 2.08 or 4.32mmol of ozone, with addition of different amounts of α-tocopherol (0.10, 0.18, and 0.26μmol). Ozonide (δ=5.15ppm) and aldehydes (δ=9.63ppm and δ=9.74ppm) intensities from ¹H NMR signals markedly decreased with α-tocopherol addition. When αtocopherol is absent, the intensities from olefinic proton signals diminished with ozone concentration increment; however, with αtocopherol in the mixture a smaller decrement was achieved. No detectable signals were found with the ozonation of α-tocopherol without methyl linoleate in the reaction mixture. These results suggest that α-tocopherol reacts with those products released from the reaction of ozone with methyl linoleate. This fact points out that antioxidant supplementation during systemic ozone therapy (major and minor autohemotherapy, rectal insufflation, and so forth) can be detrimental toward achieving the needed transient oxidative stress responsible for biological activities.     

Albert Ellis (1913–2007).

Presents an obituary for Albert Ellis (1913–2007). Albert Ellis, originator of one of the major approaches to psychotherapy in the history of psychology, Rational-Emotive Behavior Therapy (REBT), died in New York City on July 24, 2007, at 93 years of age. Ellis began his professional life as a psychoanalyst but rejected its strong focus on early-life influences and its protracted therapeutic process. In the 1950s he developed his own cognitively oriented approach to therapy, which ultimately became REBT. It has been argued that these developments represented the first step in the cognitive revolution in psychotherapy, which culminated with cognitive approaches coming to a dominant position in contemporary therapy, not unlike the parallel dominant position of cognitive psychology in psychological science. REBT has been influential worldwide, being employed by therapists in many countries but also read about and used in self-help by a wide public. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The future of positive therapy.

Responds to commentary by S. J. Lopez and B. A. Kerr (see record 2006-07640-002) on the current author's original article (see record 2006-07640-001). In their commentary on strength-centered therapy (ST), Lopez and Kerr (2006) called for an open-source approach to developing positive psychological practices. In this rejoinder, the author responds to their comments, provides clarifications on ST, and discusses the future of positive therapy. Specifically, the author calls for future scholarship to address (1) the contributions of social constructionist therapies, (2) positive systemic influences in psychotherapy, and (3) diverse conceptualizations of strengths and optimal human functioning. (PsycINFO Database Record (c) 2010 APA, all rights reserved)