电动四驱混合动力车的功率分配策略

提出了一种可适用于电动四驱混和动力车的功率分配策略。定义了综合考虑发动机效率、ISG电机效率、后轴驱动电机效率的系统总效率的表达式,用来作为功率分配的依据;提出了包括功率需求计算、电池SOC管理、功率分配表在内的功率分配模型,用来实现基于系统总效率最大的多动力源的功率分配;建立了Simulink经济性仿真平台,通过对该功率分配策略的仿真计算表明,通过该分配策略可以明显改善车辆的经济性,因而具有较好的应用前景。     

WD87型氯化物镀锌光亮剂的研究

本文简述了氯化物体系全光亮镀锌光亮剂的概况,介绍了新光亮剂—WD87的研究和它的优良性能。研究表明:氯化物体系全光亮镀锌中,光亮电流密度的上限与温度成线性关系,其直线斜率分别为;KCl 体系0.5.NaCl 体系0.3;光亮电流密度的下限与温度的对数成线性关系,KCl和 NaCl 两种体系的直线斜率相同。     

[分布式驱动电动汽车动力学控制]四轮驱动电动汽车多Agent能量管理体系研究

In order to explore the energy flow relationship of each electricity system of 4WD electric vehicles, a framework of energy managements for 4WD electric vehicles was structured based on multi-Agent system, and details of this framework were described. A mathematical model of multi-Agent system for energy managements was built with a decision-planning layer based on state transition and transferable belief model. The models of multi-Agent system for energy managements were built in Netlogo, and the energy configuration status was simulated under the rapid acceleration working conditions of electric vehicles using Netlogo. It indicates that the framework of the built energy management multi-Agent system may adjust the energy distribution weights of each Agent dynamically, and the energy allocation of each Agent maybe coordinated reasonably on the premise of satisfying dynamics requirements.     

WD615发动机可用冷却水热量分析

本文对WD615发动机各负荷工况的热平衡进行了分析,主要确定了该发动机冷却水和废气带走的热量比例,为大客车的冬季取暖做好准备。     

ATG101 Degradation by HUWE1-Mediated Ubiquitination Impairs Autophagy and Reduces Survival in Cancer Cells

Autophagy is a critical cytoprotective mechanism against stress, which is initiated by the protein kinase Unc-51-like kinase 1 (ULK1) complex. Autophagy plays a role in both inhibiting the progression of diseases and facilitating pathogenesis, so it is critical to elucidate the mechanisms regulating individual components of the autophagy machinery under various conditions. Here, we examined whether ULK1 complex component autophagy-related protein 101 (ATG101) is downregulated via ubiquitination, and whether this in turn suppresses autophagy activity in cancer cells. Knockout of ATG101 in cancer cells using CRISPR resulted in severe growth retardation and lower survival under nutrient starvation. Transfection of mutant ATG101 revealed that the C-terminal region is a key domain of ubiquitination, while co-immunoprecipitation and knockdown experiments revealed that HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1(HUWE1) is a major E3 ubiquitin ligase targeting ATG101. Protein levels of ATG101 was more stable and the related-autophagy activity was higher in HUWE1-depleted cancer cells compared to wild type (WT) controls, indicating that HUWE1-mediated ubiquitination promotes ATG101 degradation. Moreover, enhanced autophagy in HUWE1-depleted cancer cells was reversed by siRNA-mediated ATG101 knockdown. Stable ATG101 level in HUWE1-depleted cells was a strong driver of autophagosome formation similar to upregulation of the known HUWE1 substrate WD repeat domain, phosphoinositide interacting 2 (WIPI2). Cellular survival rates were higher in HUWE1-knockdown cancer cells compared to controls, while concomitant siRNA-mediated ATG101 knockdown tends to increase apoptosis rate. Collectively, these results suggest that HUWE1 normally serves to suppress autophagy by ubiquitinating and triggering degradation of ATG101 and WIPI2, which in turn represses the survival of cancer cells. Accordingly, ATG101-mediated autophagy may play a critical role in overcoming metabolic stress, thereby contributing to the growth, survival, and treatment resistance of certain cancers.     

The mei3 region of the Schizosaccharomyces pombe genome

Expression of the mei3 gene is sufficient to induce meiosis in the fission yeast Schizosaccharomyces pombe. The mei3 gene is located 0.64 Mb from the telomere of the left arm of Sz. pombe chromosome II. We have sequenced and analysed 107 kb of DNA from the mei3 genomic region. The sequence includes 14 known genes (bag1-B, csh3, dps1, gpt1, mei3, mfm3, pac1, prp31, rpl38-1, rpn3, rti1, spa1, spm1 and ubc4) and 26 other open reading frames (ORFs) longer than 100 codons: a density of one protein-coding gene per 2.7 kb. Twenty-one of the 40 ORFs (53%) have introns. In addition there is one lone Tf1 transposon long terminal repeat (LTR), tRNA(Trp) and tRNA(Ser) genes and a 5S rRNA gene. 14 of the novel ORFs show sequence similarities which suggest functions of their products, including a coatomer alpha-subunit, a catechol O-methyltransferase, protein kinase, asparagine synthetase, zinc metalloprotease, acetyltransferase, phosphatidylinositol 4-kinase, inositol polyphosphate phosphatase, GTPase-activating protein, permease, pre-mRNA splicing factor, 20S proteasome component and a thioredoxin-like protein. One predicted protein has similarity to the human Cockayne syndrome protein CSA and one with human GTPase XPA binding protein XAB1. Three ORFs are likely to code for proteins because they have sequence similarity with hypothetical proteins, three encode predicted coiled-coil proteins and four are sequence orphans.     

基于无线传感器网络的运动训练系统

根据体育训练的应用需求,利用无线传感网络技术设计了一种由嵌入式数据采集终端和数据库服务器组成的运动训练系统。硬件上设计了传感器节点和基站,实时采集运动员的运动参数。软件上设计了节点、基站控制软件及运动数据库管理系统,实现了对运动参数接收、存储、分析。并进行了系统实验,实验结果表明本系统满足体育训练的应用需求,为科学训练决策研究提供了有效工具。     

基于半监督学习和三支决策的入侵检测模型

针对现有的入侵检测模型在未知攻击上表现不佳,且标注数据极其有限的情况,提出一种基于半监督学习(SSL)和三支决策(3WD)的入侵检测模型——SSL-3WD.SSL-3WD模型通过3WD在信息不足情况下的优秀表现来满足SSL在数据信息的充分冗余性上的假设.首先利用3WD理论对网络行为数据进行分类,而后根据分类结果选择适当...     

斯太尔WD615系列柴油机润滑系的正确使用

通过同一台车的柴油机在间隔不到一年的时间内两次烧瓦事故的实例,叙述WD615柴油机润滑系的正确使用。