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81.
Ramanath N. Bhat Rajiv Kumar 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》1990,48(4):453-466
The feasibility of synthesising pure zeolite beta in high yields using silica gel as the source of SiO2 is demonstrated. The phase-purity and yield of beta is enhanced by using silica gels with high surface area. The influence of various synthesis parameters (Si/Al ratio, alkalinity, dilution level, concentration of the organic base, etc.) on the kinetics of synthesis as well as the quality and yield of the zeolite have been investigated. A correlation between XRD crystallinity of the samples with varying degrees of crystallinity and that estimated from framework IR spectroscopy, differential thermal analysis and adsorption of n-hexane is demonstrated. The dependence of the yield of zeolite beta on SiO2/Al2O3 ratio of the gel is also reported. The results of the present study indicate the feasibility of a cheaper route for the manufacture of zeolite beta. 相似文献
82.
Sedimentary facies are important in reservoir characterization because flow properties are commonly assigned using facies-specific correlations. Multivariate statistical methods provide a powerful vehicle to extract facies responses from different well logs, to predict facies in uncored wells and evaluate uncertainty.Previous study shows a difficulty in bin selection to accurately reproduce the samples' conditional probability distribution. In this paper, a new method uses empirical beta distributions to model the distribution of petrophysical properties conditional to facies. Petrophysical property distributions are assumed conditionally independent, simplifying the use of Bayes rule.Three multivariate statistical methods (beta-Bayesian, multinomial logistic regression, and discriminant analysis) are examined in this paper using log and facies data from a western African sandstone reservoir. Three derived probability logs compare the prediction performance of the statistical methods as well as illustrate influences of log combinations and sample size. Two-way analysis of variance compares prediction accuracy of the models. For a given dataset, there are no significant differences (with 90% confidence) in predictions by the three methods. Additional logs improve prediction accuracy from 30 to above 80%. Final prediction accuracy is 82 to 90% for these three algorithms. Including 20 to 25% of the complete core and facies data in model construction provides accurate predictions; models were validated against the data not used in model construction. The fitted classification models can generate three-dimensional log-derived facies distributions for geologic modeling and reservoir simulation. The three methods are straightforward, efficient, and have quantifiable prediction errors. 相似文献
83.
Kang Shanjiao Dou Tao Li Qiang Duan Aijun Zheng Yanying Pan Huifang 《Journal of Porous Materials》2008,15(2):159-162
This paper presents the direct synthesis of super-low SiO2/Al2O3 ratio zeolite beta molecular sieve through a novel route, by which some of aluminium species are added during crystaling
process. The IR results show that with the increase of aluminium content in the framework, the frequency of the band in the
range of framework vibration (1060–1090 cm−1) shifts to the lower wave-number; the BET surface-area decreases and the basicity of zeolite becomes stronger. In a second
step, new adsorbents were obtained by solid-state ion exchanging zeolite beta with Cu(I), Ag(I) cations. The deep-desulfurization
(sulfur levels of <1 ppmw) tests were performed using fixed-bed adsorption technique, the sulfur content of the treated and
untreated gasoline was analyzed by microcoulometry. The experimental results show that the desulfurization performance of
sorbents decreases in order: Cu(I)beta > Ag(I)beta > Na-beta. The best sorbent, Cu(I)beta, has breakthrough adsorption capacities
of 0.236 mmolS/g of sorbent for model gasoline. 相似文献
84.
目的 在不同固溶热处理工艺的β钛合金上制备微弧氧化膜,研究其在微弧氧化初期的生长特性。方法 对比铸态、750 ℃固溶、850 ℃固溶β钛合金表面微弧氧化初期(0~120 s)氧化膜的厚度、表面形貌、相组成及电化学腐蚀性能变化,研究热处理与膜层特性之间的关系,并分析热处理对氧化膜表面裂纹的产生及膜层生长的影响规律。结果 固溶处理改变了基体合金的相组成,元素分布随之改变,热处理后试样表面更容易起弧。较未热处理试样,氧化时间为120 s时,固溶处理后所获膜层的厚度更薄且致密。微弧氧化膜微观形貌显示,经750 ℃固溶热处理后的试样,在微弧氧化后,其膜层表面裂纹最少。极化曲线显示,750 ℃热处理试样氧化膜的耐蚀性优于850 ℃热处理试样。结论 经过750 ℃固溶处理后的合金试样,由于其元素分布均匀,使得微弧氧化初期放电均匀,更易获得致密的微弧氧化膜,膜层的综合性能较好。 相似文献
85.
The consumption of omega‐3 polyunsaturated fatty acids (n‐3 PUFA) is associated with a reduced risk of breast cancer. Studies in animals and in vitro have demonstrated mechanisms that could explain this apparent effect, but clinical and epidemiological studies have returned conflicting results on the practical benefits of dietary n‐3 PUFA for prevention of breast cancer. Effects are often only significant within a population when comparing the highest n‐3 PUFA consumption group to the lowest n‐3 group or highest n‐6 group. The beneficial effects of n‐3 PUFA eicosapentaenoic and docosahexaenoic on the risk of breast cancer are dose dependent and are negatively affected by total n‐6 consumption. The majority of the world population, including the most highly developed regions, consumes insufficient n‐3 PUFA to significantly reduce breast cancer risk. This review discusses the physiological and dietary context in which reduction of breast cancer risk may occur, some proposed mechanisms of action and meaningful recommendations for consumption of n‐3 PUFA in the diet of developed regions. 相似文献
86.
Aggregation‐Prone Amyloid‐β⋅CuII Species Formed on the Millisecond Timescale under Mildly Acidic Conditions 下载免费PDF全文
Prof. Dr. Jeppe T. Pedersen Christian B. Borg Thomas C. T. Michaels Dr. Tuomas P. J. Knowles Prof. Dr. Peter Faller Prof. Dr. Kaare Teilum Prof. Dr. Lars Hemmingsen 《Chembiochem : a European journal of chemical biology》2015,16(9):1293-1297
Metal ions and their interaction with the amyloid beta (Aβ) peptide might be key elements in the development of Alzheimer's disease. In this work the effect of CuII on the aggregation of Aβ is explored on a timescale from milliseconds to days, both at physiological pH and under mildly acidic conditions, by using stopped‐flow kinetic measurements (fluorescence and light‐scattering), 1H NMR relaxation and ThT fluorescence. A minimal reaction model that relates the initial CuII binding and Aβ folding with downstream aggregation is presented. We demonstrate that a highly aggregation prone Aβ ? CuII species is formed on the sub‐second timescale at mildly acidic pH. This observation might be central to the molecular origin of the known detrimental effect of acidosis in Alzheimer's disease. 相似文献
87.
ATP合酶,又称F1F0-ATP合成酶,是位于线粒体内膜、叶绿体类囊体膜和光合菌质膜上的参与呼吸链氧化磷酸化的最后环节。其结构包含F1和F0两个亚单位,共同作用于ATP的分解和合成。ATP合酶β亚基是F1F0-ATP合成酶F1亚单位的重要组件,该亚基包含ATP合成和水解所需的催化位点,其功能好坏与疾病发生直接相关。本文就ATP合酶β亚基功能与糖尿病、肿瘤、肥胖症等疾病的关系作一综述。 相似文献
88.
Pavel L. Katsel Tamara M. Dmitrieva Rashid B. Valeyev Yuri P. Kozlov 《Journal of chemical ecology》1992,18(11):2003-2010
Three components of the male yellowfin Baikal sculpin pheromonal signal have been isolated from urine by diethyl ether extraction, thinayer chromatography (TLC), and high-performance liquid chromatography (HPLC). Using mass spectrometry, we have identified two of them as testosterone (T) and 11beta" align="MIDDLE" BORDER="0">-hydroxytestosterone (11HT). These steroids are synthesized in testes during full spermatogenesis, and they are excreted in male urine with milt. The third component is not a steroid. It is more likely to be a polyene alcohol (farnesol). 2Z,6E-Farnesol possesses behavioral activity. 相似文献
89.
本实验用LACA成年雄鼠分别接受0. 19,0. 38,0.66和1. 01Gy的氚水β射线和0. 743,1.592和2.074Gy的~(60)Coγ射线分别连续照射10天。诱发精细胞显性致死突变率分别为8.6%—14.9%和4.4%—30.3%。两种射线的剂量响应关系为线性,根据二条直线斜率之比求出氚的RBE值为2.1。 相似文献
90.
Bianca Papotti Maria Pia Adorni Cinzia Marchi Francesca Zimetti Nicoletta Ronda Giovanni Panighel Maria Giovanna Lupo Antonietta Vilella Daniela Giuliani Nicola Ferri Franco Bernini 《International journal of molecular sciences》2022,23(20)
The Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) involvement in Alzheimer’s disease (AD) is poorly investigated. We evaluated the in vitro PCSK9 modulation of astrocyte cholesterol metabolism and neuronal cholesterol supplying, which is fundamental for neuronal functions. Moreover, we investigated PCSK9 neurotoxic effects. In human astrocytoma cells, PCSK9 reduced cholesterol content (−20%; p < 0.05), with a greater effect in presence of beta amyloid peptide (Aβ) (−37%; p < 0.01). PCSK9 increased cholesterol synthesis and reduced the uptake of apoE-HDL-derived cholesterol (−36%; p < 0.0001), as well as the LDL receptor (LDLR) and the apoE receptor 2 (ApoER2) expression (−66% and −31%, respectively; p < 0.01). PCSK9 did not modulate ABCA1- and ABCG1-cholesterol efflux, ABCA1 levels, or membrane cholesterol. Conversely, ABCA1 expression and activity, as well as membrane cholesterol, were reduced by Aβ (p < 0.05). In human neuronal cells, PCSK9 reduced apoE-HDL-derived cholesterol uptake (−41%; p < 0.001) and LDLR/apoER2 expression (p < 0.05). Reduced cholesterol internalization occurred also in PCSK9-overexpressing neurons exposed to an astrocyte-conditioned medium (−39%; p < 0.001). PCSK9 reduced neuronal cholesterol content overall (−29%; p < 0.05) and increased the Aβ-induced neurotoxicity (p < 0.0001). Our data revealed an interfering effect of PCSK9, in cooperation with Aβ, on brain cholesterol metabolism leading to neuronal cholesterol reduction, a potentially deleterious effect. PCSK9 also exerted a neurotoxic effect, and thus represents a potential pharmacological target in AD. 相似文献